Patents by Inventor Siraj Ali

Siraj Ali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240112757
    Abstract: A method of characterizing a cancer, such as a combined hepatocellular cholangiocarcinoma (cHCC-CCA), as hepatocellular carcinoma (HCC)-like or cholangiocarcinoma (CCA)-like are described herein, as well as electronic devices and non-transitory computer readable storage mediums for implementing such methods. Also described are methods of treating a cancer, such as cHCC-CCA, characterized as HCC-like or CCA-like. The cancer can be characterized as CCA-like or HCC-like using a cHCC-CCA machine-learning model trained using HCC data from a plurality of HCC samples and CCA data from a plurality of CCA samples. The HCC data, CCA data, and the data from the cancer test sample can include one or more features, such as features from a genomic profile. Exemplary features include tumor purity, a chromosomal aneuploidy status for one or more chromosomes or chromosome arms, and a cancer cell fraction (CCF) for one or more genes differentially represented in CCA and HCC, among others.
    Type: Application
    Filed: January 27, 2022
    Publication date: April 4, 2024
    Applicant: Foundation Medicine, Inc.
    Inventors: Karthikeyan MURUGESAN, Siraj ALI, Yutong QIU, Kimberly MCGREGOR
  • Publication number: 20220396839
    Abstract: Provided herein are methods for detecting a Ewing sarcoma breakpoint region 1 (EWSR1) fusion gene encoding a neoantigen (e.g., in a patient sample), as well as methods of prognosis and treatment related thereto, in some embodiments, the methods further comprise administering a cancer immunotherapy. In some embodiments, the EWSR1 fusion gene is a fusion gene between EWSR1 and WT1, Fill, ERG, FEV, NR4A3, ATF1, CREB1, CREM, CREB3L/CREB3L2, PA7Z1, NFATC2, KLFI5, C11orf93, ZNF444, PBX1, DDIT3, or TFCP2 that encodes a neoantigen.
    Type: Application
    Filed: November 10, 2020
    Publication date: December 15, 2022
    Applicant: Foundation Medicine, Inc.
    Inventors: Dexter X. JIN, Ethan SOKOL, Sally TRABUCCO, Dean PAVLICK, Siraj ALI
  • Patent number: 11487841
    Abstract: Various embodiments are generally directed to techniques for selecting a user experience design in a time-critical environment, such as based on the results of multiple classification processes while maintaining appropriate responsiveness, for instance. Some embodiments are particularly directed to selecting a website design experience based on results, or lack thereof, provided by a plurality of inference processes of varying accuracy within a predefined amount of time. For example, a page request, or indication thereof, may be received by an inference manager from a client device. In response to the page request, the inference manager may initiate one or more inference processes, and based on the response, or lack thereof, from each of the one or more inference process within a predetermine amount of time, the inference manager may provide an indication to an experience design selector.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: November 1, 2022
    Assignee: Capital One Services, LLC
    Inventors: Jonathan Rider, Siraj Ali, Anderson Osagie
  • Publication number: 20210073311
    Abstract: Various embodiments are generally directed to techniques for selecting a user experience design in a time-critical environment, such as based on the results of multiple classification processes while maintaining appropriate responsiveness, for instance. Some embodiments are particularly directed to selecting a website design experience based on results, or lack thereof, provided by a plurality of inference processes of varying accuracy within a predefined amount of time. For example, a page request, or indication thereof, may be received by an inference manager from a client device. In response to the page request, the inference manager may initiate one or more inference processes, and based on the response, or lack thereof, from each of the one or more inference process within a predetermine amount of time, the inference manager may provide an indication to an experience design selector.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 11, 2021
    Applicant: Capital One Services, LLC
    Inventors: Jonathan RIDER, Siraj ALI, Anderson OSAGIE
  • Patent number: 10853442
    Abstract: Various embodiments are generally directed to techniques for selecting a user experience design in a time-critical environment, such as based on the results of multiple classification processes while maintaining appropriate responsiveness, for instance. Some embodiments are particularly directed to selecting a website design experience based on results, or lack thereof, provided by a plurality of inference processes of varying accuracy within a predefined amount of time. For example, a page request, or indication thereof, may be received by an inference manager from a client device. In response to the page request, the inference manager may initiate one or more inference processes, and based on the response, or lack thereof, from each of the one or more inference process within a predetermine amount of time, the inference manager may provide an indication to an experience design selector.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: December 1, 2020
    Assignee: Capital One Services, LLC
    Inventors: Jonathan Rider, Siraj Ali, Anderson Osagie