Patents by Inventor Siripalli Udaya Bhaskara Rao

Siripalli Udaya Bhaskara Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alternative process for the preparation of losartan
    Patent number: 7923566
    Abstract: The invention relates to an improved process for the preparation of Losartan. The process comprising reacting 2-n-butyl-4-chloro-5-formyl imidazole with 2-(4-bromomethyl) benzonitrile in the presence of a phase transfer catalyst and an alkali, and reducing the resulting cyano aldehyde to produce a cyano alcohol which is further reacted with sodium azide in N-methyl pyrrolidinone and a salt to produce Losartan.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: April 12, 2011
    Assignee: Suven Life Sciences Limited
    Inventors: Arava Veera Reddy, Siripalli Udaya Bhaskara Rao, Chinnapillai Rajendiran, Venkateswarlu Jasti
  • Process for the preparation of losartan
    Patent number: 7915425
    Abstract: The invention relates to a improved process for the preparation of Losartan and its potassium salt, which comprises: (i) reacting bromo OTBN with BCFI in the presence of a base and a phase transfer catalyst to produce a cyano aldehyde; reacting the formed cyano aldehyde with sodium azide in the presence of tributyl tin chloride to produce aldehyde tetrazole; reducing the formed aldehyde tetrazole with sodium borohydride to produce Losartan; and, if desired, converting the formed Losartan to its potassium salt by known method.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: March 29, 2011
    Assignee: Suven Life Sciences Limited
    Inventors: Arava Veera Reddy, Siripalli Udaya Bhaskara Rao, Chinnapillai Rajendiran, Venkateswarlu Jasti
  • Process for the Preparation of Losartan
    Publication number: 20100190996
    Abstract: The invention relates to an improved process for the preparation of Losartan. The process comprising reacting 2-n-butyl-4-chloro-5-formyl imidazole with 2-(4-bromomethyl) benzonitrile in the presence of a phase transfer catalyst and an alkali, and reducing the resulting cyano aldehyde to produce a cyano alcohol which is further reacted with sodium azide in N-methyl pyrrolidinone and a salt to produce Losartan.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 29, 2010
    Applicant: Suven Life Sciences, Ltd
    Inventors: Arava Veera Reddy, Siripalli Udaya Bhaskara Rao, Chinnapillai Rajendrian, Vankateswarlu Jasti