Patents by Inventor Sirlei Daffre

Sirlei Daffre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7723468
    Abstract: The invention refers to small peptides with low hemolytic activity, presenting similar antiparasitic, antifungal and antibacterial activities. More specifically, it refers to a peptide called gomesin, with 18 amino acid residues, configured as a hairpin structure consisting of two anti-parallel beta-folded sheets joined by a beta turn, containing four invariable residues of cysteine forming two disulphide bridges, configurable as a cyclic chain with open or closed ends.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: May 25, 2010
    Assignee: De Sao Paulo Universida de
    Inventors: Sirlei Daffre, Pedro Ismael Da Silva, Jr., Philippe Bulet
  • Publication number: 20060276380
    Abstract: The invention refers to small peptides with low hemolytic activity, presenting similar antiparasitic, antifungal and antibacterial activities. More specifically, it refers to a peptide called gomesin, with 18 amino acid residues, configured as a hairpin structure consisting of two anti-parallel beta-folded sheets joined by a beta turn, containing four invariable residues of cysteine forming two disulphide bridges, configurable as a cyclic chain with open or closed ends.
    Type: Application
    Filed: May 10, 2006
    Publication date: December 7, 2006
    Inventors: Sirlei Daffre, Pedro De Silva Jr, Philippe Bulet
  • Publication number: 20030186854
    Abstract: The invention refers to small peptides with low hemolytic activity, presenting equal antiparasitic, antifungal and antibacterial activities. More specifically, it refers to a peptide called gomesin, with 18 amino acid residues, configured as a clamp-like structure consisting of two anti-parallel beta-folded sheets joined by a beta turn, containing four invariable residues of cystein forming two disulphide bridges, optionally configurable as a cyclic chain with closed edges.
    Type: Application
    Filed: February 27, 2003
    Publication date: October 2, 2003
    Inventors: Sirlei Daffre, Pedro Ismael da Silva