Patents by Inventor Sisi Chen

Sisi Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12509715
    Abstract: An nucleic acid integrated detection method is provided, the method includes separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: December 30, 2025
    Assignee: USTAR Biotechnologies (Hangzhou) Ltd.
    Inventors: Qimin You, Lin Hu, Chen Qi, Junwei Yu, Zhujun Yu, Sha Wang, Rongyu Jin, Daisang Wang, Sisi Chen, Junli He, Jing Chen, Huanxin Rao, Yanqiong Zhou, Fan Yang
  • Patent number: 12503371
    Abstract: The present disclosure discloses a method for strengthening a biological manganese oxidation using a magnetic field and use thereof. The method includes steps of inoculating a manganese-oxidizing microorganism into a culture medium containing Mn2+, performing magnetization treatment in a culture process, and then collecting a biogenic manganese oxide. The method includes steps of performing a primary magnetic field treatment at a magnetic field intensity of 0.2-50 mT for 1-5 h when culturing is performed for 6-12 h, continuing culturing after the primary magnetization treatment, and performing magnetization treatment once every other 24 h for culture time of 72 h. A magnetic field is applied to accelerate an oxidation rate of a manganese-oxidizing microorganism to Mn2+ and a biological manganese oxidation rate is respectively improved by 36.4% and 23.8% under an action of an alternating magnetic field or a constant magnetic field within 72 h.
    Type: Grant
    Filed: March 6, 2023
    Date of Patent: December 23, 2025
    Assignee: TONGJI UNIVERSITY
    Inventors: Mei Wang, Zuxin Xu, Bin Dong, Mengke Cui, Sisi Chen, Yifan Zeng, Chun Lu
  • Patent number: 12465917
    Abstract: An nucleic acid integrated detection reagent tube is provided, it includes a main tube and one or more branch tubes, wherein a lysing zone, a cleaning zone and a plurality of separation plugs comprising at least a least a separation plug and a second separation plug which are sequentially disposed, the first separation plug is used for separating the lysing zone and the cleaning zone, a reaction zone is provided in the branch tubes and the second separation plug is positioned at a connection between the branch tubes and the main tube or inside the branch tubes; hydrophobic layers in a liquid or a solid phase disposed at each of the plurality of separation plugs; and a magnetic bead channel for magnetically carrying the nucleic acid to sequentially pass through each hydrophobic layer penetrating to the branch tubes defined in an inner wall of the detection reagent tube.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: November 11, 2025
    Assignee: USTAR Biotechnologies (Hangzhou) Ltd.
    Inventors: Qimin You, Lin Hu, Chen Qi, Junwei Yu, Zhujun Yu, Sha Wang, Rongyu Jin, Daisang Wang, Sisi Chen, Junli He, Jing Chen, Huanxin Rao, Yanqiong Zhou, Fan Yang
  • Publication number: 20250320315
    Abstract: Disclosed is a Bletilla striata polysaccharide, its preparation method and use, an immune adjuvant and a nano vaccine containing the Bletilla striata polysaccharide. The Bletilla striata polysaccharide of the disclosure has the immunomodulatory effect. The Bletilla striata polysaccharide and the protein vaccine are self-assembled to generate the nano vaccine after mixing, and the self-assembled nano vaccine is relatively uniform round particles. When the nano vaccine is used to immunize mice, it is able to activate antigen presenting cells (APCs) and improve their uptake of antigen. The nano vaccine enables mice to generate antibody and cell response which are 2-10 times stronger than that of the traditional vaccines.
    Type: Application
    Filed: May 12, 2021
    Publication date: October 16, 2025
    Inventors: Jiangmiao HU, Ye LIU, Liu YANG, Sisi CHEN, Jinyu LI
  • Publication number: 20250084312
    Abstract: Disclosed is a method for improving alkaline soil and enhancing carbon capture using a sludge stabilization product. The method includes the following steps: subjecting sludge to aerobic composting to obtain a stabilized product A; subjecting one part of the stabilized product A to extraction to obtain humus B; subjecting the other part of the stabilized product A to hydrothermal extraction to obtain a soluble organic matter rich in amino acids and organic salts, and conducting evaporation to dryness to obtain a mixture C; subjecting a residue obtained during the extraction of the humus B and the mixture C to pyrolysis to obtain biochar D rich in metal oxides; mixing the stabilized product A, the humus B, the mixture C, and the biochar D fully to obtain a soil amendment E; and applying the soil amendment E to a surface layer of alkaline soil, and then cultivating a plant.
    Type: Application
    Filed: May 18, 2023
    Publication date: March 13, 2025
    Inventors: Bin DONG, Sisi CHEN, Jun GAO, Zuxin XU
  • Publication number: 20250016483
    Abstract: Embodiments of the present application relate the technical filed of optical communications, in particular to a traffic processing method and an apparatus for an optical transport network, an electronic device, and a storage medium. The traffic processing method includes: obtaining an acquisition mode control signal for designating a type of a payload block (PB) to be acquired; performing data acquisition on a PB of an optical channel payload unit (OPU) frame mapped and multiplexed from an optical service unit (OSU) frame according to the designated type of the PB to be acquired to obtain acquired data; performing data statistics of the designated type of the PB according to the acquired data.
    Type: Application
    Filed: February 28, 2022
    Publication date: January 9, 2025
    Inventor: Sisi CHEN
  • Publication number: 20250007638
    Abstract: A mapping and multiplexing method for an optical transport network, an electronic device, and a storage medium are provided. The method includes: first providing a mapping opportunity generated by an OPU in a current transport window to one or more OSU services, which satisfy a first scheduling condition, in a first queue, and performing in-queue scheduling on the one or more OSU services; in a case where there is no OSU service satisfying the first scheduling condition in the first queue, providing the mapping opportunity to one or more OSU services, which satisfy a second scheduling condition, in a second queue, and performing in-queue scheduling on the one or more OSU services; updating a remaining service mapping opportunity quantity of the OSU service which gets the mapping opportunity; and dynamically allocating OSU services entering mapping and multiplexing in the current transport window to the first queue and the second queue.
    Type: Application
    Filed: February 28, 2022
    Publication date: January 2, 2025
    Inventor: Sisi CHEN
  • Publication number: 20240424020
    Abstract: An endogenous chimeric antigen receptor (ECAR) has an antigen-binding domain that is an endogenous protein molecule. The engineered immune cells expressing the ECAR can kill a variety of cells specifically and selectively.
    Type: Application
    Filed: January 24, 2022
    Publication date: December 26, 2024
    Inventors: Songmin YING, Sisi CHEN
  • Patent number: 12119926
    Abstract: Provided are a time synchronization method and device, and a storage medium. The method includes that: a synchronized block matching a preset code pattern in a data stream is searched at a SERDES parallel interface; the position of the bit of the synchronized block in the SERDES parallel interface is determined as a first position; a time point when the synchronized block passes through the SERDES parallel interface is determined as a first time point; the synchronized block and a PTP packet in the data stream are searched at an interface between PHY layer and MAC layer, and a distance between the synchronized block and the PTP packet is determined; and a second time point is determined according to the first position, the first time point and the distance, the second time point being the time point when the PTP packet passes through an SERDES serial interface.
    Type: Grant
    Filed: September 29, 2019
    Date of Patent: October 15, 2024
    Assignee: SANECHIPS TECHNOLOGY CO., LTD.
    Inventor: Sisi Chen
  • Publication number: 20240272777
    Abstract: This application discloses a method and apparatus for processing an incoming call display interface and an electronic device. The method includes: displaying an incoming call display interface, where the incoming call display interface includes a target element, and the target element is displayed with a first effect; receiving a first input from a user; and in response to the first input, displaying the target element with a second effect in a case that the first input indicates answering an incoming call, and displaying the target element with a third effect in a case that the first input indicates rejecting an incoming call.
    Type: Application
    Filed: May 2, 2024
    Publication date: August 15, 2024
    Inventor: Sisi CHEN
  • Publication number: 20240217856
    Abstract: The present disclosure discloses a method for preparing a sludge conditioner from water supply sludge and a use of the sludge conditioner. The sludge conditioner is prepared by mixing the water supply sludge and sewage sludge. The method includes the following steps: mixing the water supply sludge and the sewage sludge in proportion, adding a pore forming agent, stirring a mixture uniformly, and conducting mechanical dehydration, air-drying, grinding, sieving, and pyrolysis to obtain the sludge conditioner. The conditioner is used in advanced oxidation technologies such as catalyzed/activated ozone oxidation, persulfate oxidation, and Fenton oxidation to condition the sludge and enhance dehydration performance.
    Type: Application
    Filed: July 27, 2022
    Publication date: July 4, 2024
    Inventors: Bin DONG, Tingting XIAO, Zuxin XU, Haibin WU, Dianchang WANG, Chong LI, Danni SHEN, Xiankai WANG, Feng LIU, Sisi CHEN
  • Patent number: 12006271
    Abstract: A method for sludge dewatering using kitchen waste to synergistically enhance a coupling of an anaerobic biological acidification and a low-temperature hydrothermal of excess sludge is disclosed. The method includes the following steps: first, uniformly mixing the excess sludge from a sewage treatment plant and the kitchen waste for an anaerobic biological acidification reaction at 36.5-37.5° C. for 2-4 days; then, concentrating the acidified mixture by centrifugation at a speed of 3000-5000 rpm for 5-10 min; performing a low-temperature thermal hydrolysis treatment on a residue obtained after removing a supernatant for 15-30 min at 100-140° C.; and after the thermal hydrolysis treatment is finished, cooling and dewatering to obtain a dewatered sludge cake and a dewatered filtrate. The new method realizes high-efficiency sludge dewatering and innocuous utilization of dewatered filtrate and sludge cake without adding chemical reagents and effectively avoids generating hardly-degradable chemical oxygen demand.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: June 11, 2024
    Assignee: TONGJI UNIVERSITY
    Inventors: Bin Dong, Sisi Chen, Jun Gao, Renjie Chen, Xiangjuan Sun, Zao Yang, Bing Xue
  • Publication number: 20230344895
    Abstract: One disclosed method involves receiving, by a first application executing on a first client device, a link to download a file from a computing system, presenting, by the first application and via the first client device, a user interface element that, when selected, causes the first application to request a second application executing on a second client device to initiate a process for downloading the file from the computing system using the link, in response to detecting selection of the user interface element, sending, by the first application, a request to the second application to initiate the process, and receiving, by the first client device, the file that the second application caused download of from the computing system using the link.
    Type: Application
    Filed: May 17, 2022
    Publication date: October 26, 2023
    Inventors: Tianze Jiang, Sisi Chen
  • Publication number: 20230202855
    Abstract: The present disclosure discloses a method for strengthening a biological manganese oxidation using a magnetic field and use thereof. The method includes steps of inoculating a manganese-oxidizing microorganism into a culture medium containing Mn2+, performing magnetization treatment in a culture process, and then collecting a biogenic manganese oxide. The method includes steps of performing a primary magnetic field treatment at a magnetic field intensity of 0.2-50 mT for 1-5 h when culturing is performed for 6-12 h, continuing culturing after the primary magnetization treatment, and performing magnetization treatment once every other 24 h for culture time of 72 h. A magnetic field is applied to accelerate an oxidation rate of a manganese-oxidizing microorganism to Mn2+and a biological manganese oxidation rate is respectively improved by 36.4% and 23.8% under an action of an alternating magnetic field or a constant magnetic field within 72 h.
    Type: Application
    Filed: March 6, 2023
    Publication date: June 29, 2023
    Applicant: TONGJI UNIVERSITY
    Inventors: Mei Wang, Zuxin Xu, Bin Dong, Mengke CUI, Sisi Chen, Yifan ZENG, Chun LU
  • Patent number: 11548803
    Abstract: The present invention relates to a method for enhancing deep degradation of proteins in sludge.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: January 10, 2023
    Assignee: TONGJI UNIVERSITY
    Inventors: Bin Dong, Sisi Chen, Jun Gao, Danni Shen
  • Publication number: 20220126286
    Abstract: An nucleic acid integrated detection reagent tube is provided, it includes a main tube and one or more branch tubes, wherein a lysing zone, a cleaning zone and a plurality of separation plugs comprising at least a least a separation plug and a second separation plug which are sequentially disposed, the first separation plug is used for separating the lysing zone and the cleaning zone, a reaction zone is provided in the branch tubes and the second separation plug is positioned at a connection between the branch tubes and the main tube or inside the branch tubes; hydrophobic layers in a liquid or a solid phase disposed at each of the plurality of separation plugs; and a magnetic bead channel for magnetically carrying the nucleic acid to sequentially pass through each hydrophobic layer penetrating to the branch tubes defined in an inner wall of the detection reagent tube.
    Type: Application
    Filed: December 30, 2021
    Publication date: April 28, 2022
    Applicant: USTAR Biotechnologies (Hangzhou) Ltd.
    Inventors: Qimin YOU, Lin HU, Chen QI, Junwei YU, Zhujun YU, Sha WANG, Rongyu JIN, Daisang WANG, Sisi CHEN, Junli HE, Jing CHEN, Huanxin RAO, Yanqiong ZHOU, Fan YANG
  • Publication number: 20220119863
    Abstract: An nucleic acid integrated detection method is provided, the method includes separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.
    Type: Application
    Filed: December 30, 2021
    Publication date: April 21, 2022
    Applicant: USTAR Biotechnologies (Hangzhou) Ltd.
    Inventors: Qimin YOU, Lin HU, Chen QI, Junwei YU, Zhujun YU, Sha WANG, Rongyu JIN, Daisang WANG, Sisi CHEN, Junli HE, Jing CHEN, Huanxin RAO, Yanqiong ZHOU, Fan YANG
  • Patent number: 11242552
    Abstract: A nucleic acid integrated detection method and detection reagent tube are provided, separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: February 8, 2022
    Assignee: USTAR Biotechnologies (Hangzhou) Ltd.
    Inventors: Qimin You, Lin Hu, Chen Qi, Junwei Yu, Zhujun Yu, Sha Wang, Rongyu Jin, Daisang Wang, Sisi Chen, Junli He, Jing Chen, Huanxin Rao, Yanqiong Zhou, Fan Yang
  • Publication number: 20220021513
    Abstract: The present disclosure discloses a delay jitter compensation method and device, and a computer storage medium. The method includes: determining, by a time stamp compensation component, a current delay jitter of a data link layer according to the latest recorded data cumulant and a fixed value of data cumulant, the fixed value of data cumulant indicating a value of data cumulant without any delay jitter in the data link layer; and acquiring, by the time stamp compensation component, an initial time stamp recorded in a protocol layer, and compensating the initial time stamp according to the current delay jitter of the data link layer to obtain a compensated time stamp, the compensated time stamp being a time stamp obtained by compensating the initial time stamp.
    Type: Application
    Filed: December 16, 2019
    Publication date: January 20, 2022
    Inventor: Sisi CHEN
  • Publication number: 20220006546
    Abstract: Provided are a time synchronization method and device, and a storage medium. The method includes that: a synchronized block matching a preset code pattern in a data stream is searched at a SERDES parallel interface; the position of the bit of the synchronized block in the SERDES parallel interface is determined as a first position; a time point when the synchronized block passes through the SERDES parallel interface is determined as a first time point; the synchronized block and a PTP packet in the data stream are searched at an interface between PHY layer and MAC layer, and a distance between the synchronized block and the PTP packet is determined; and a second time point is determined according to the first position, the first time point and the distance, the second time point being the time point when the PTP packet passes through an SERDES serial interface.
    Type: Application
    Filed: September 29, 2019
    Publication date: January 6, 2022
    Inventor: Sisi CHEN