Patents by Inventor Sita Awasthi

Sita Awasthi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED MRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF
    Publication number: 20240024463
    Abstract: The present invention provides compositions for the prevention and treatment of genital herpes, comprising nucleoside modified mRNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
    Type: Application
    Filed: September 19, 2023
    Publication date: January 25, 2024
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey FRIEDMAN, Drew WEISSMAN, Sita AWASTHI, Gary Cohen
  • RNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF
    Publication number: 20240016922
    Abstract: The present disclosure provides compositions for the prevention and treatment of genital herpes, comprising nucleoside-modified RNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
    Type: Application
    Filed: August 3, 2023
    Publication date: January 18, 2024
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey FRIEDMAN, Sita AWASTHI, Gary Cohen, Drew WEISSMAN
  • Modified MRNA vaccines encoding herpes simplex virus glycoproteins and uses thereof
    Patent number: 11793872
    Abstract: Compositions for the prevention and treatment of genital herpes, comprising nucleoside modified mRNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: October 24, 2023
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey Friedman, Drew Weissman, Sita Awasthi, Gary Cohen
  • MODIFIED MRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF
    Publication number: 20210386853
    Abstract: The present invention provides compositions for the prevention and treatment of genital herpes, comprising nucleoside modified mRNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 16, 2021
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey FRIEDMAN, Drew WEISSMAN, Sita AWASTHI, Gary Cohen
  • Modified mRNA vaccines encoding herpes simplex virus glycoproteins and uses thereof
    Patent number: 11141478
    Abstract: The present invention provides compositions for the prevention and treatment of genital herpes, comprising nucleoside modified m RNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: October 12, 2021
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey Friedman, Drew Weissman, Sita Awasthi, Gary Cohen
  • MODIFIED MRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF
    Publication number: 20200276300
    Abstract: The present invention provides compositions for the prevention and treatment of genital herpes, comprising nucleoside modified m RNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
    Type: Application
    Filed: August 17, 2018
    Publication date: September 3, 2020
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey FRIEDMAN, Drew WEISSMAN, Sita AWASTHI, Gary Cohen
  • Herpes simplex virus combined subunit vaccines and methods of use thereof
    Patent number: 10478490
    Abstract: This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV thereby vaccinating a subject against HSV and treating, suppressing, inhibiting, and/or reducing an incidence of an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: November 19, 2019
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Harvey Friedman, Sita Awasthi, John Lubinski
  • HERPES SIMPLEX VIRUS COMBINED SUBUNIT VACCINES AND METHODS OF USE THEREOF
    Publication number: 20130028925
    Abstract: This invention provides immunogenic compositions comprising two or three recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV, inducing an anti-HSV immune response, and treating, suppressing, inhibiting, and/or reducing an incidence of an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.
    Type: Application
    Filed: June 4, 2012
    Publication date: January 31, 2013
    Inventors: Harvey FRIEDMAN, Sita Awasthi, John Lubinski
  • Herpes simplex virus combined subunit vaccines and methods of use thereof
    Patent number: 8057804
    Abstract: This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV thereby vaccinating a subject against HSV and treating, suppressing, inhibiting, and/or reducing an incidence of an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: November 15, 2011
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Harvey Friedman, Sita Awasthi, John Lubinski
  • HERPES SIMPLEX VIRUS COMBINED SUBUNIT VACCINES AND METHODS OF USE THEREOF
    Publication number: 20110256176
    Abstract: This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV thereby vaccinating a subject against HSV and treating, suppressing, inhibiting, and/or reducing an incidence of an an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.
    Type: Application
    Filed: November 13, 2008
    Publication date: October 20, 2011
    Inventors: Harvey FRIEDMAN, Sita AWASTHI, John LUBINSKI
  • HERPES SIMPLEX VIRUS COMBINED SUBUNIT VACCINES AND METHODS OF USE THEREOF
    Publication number: 20090148467
    Abstract: This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV thereby vaccinating a subject against HSV and treating, suppressing, inhibiting, and/or reducing an incidence of an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.
    Type: Application
    Filed: July 24, 2008
    Publication date: June 11, 2009
    Inventors: Harvey Friedman, Sita Awasthi, John Lubinski
  • Herpes simplex virus combined subunit vaccines and methods of use thereof
    Publication number: 20090098162
    Abstract: This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of vaccinating a subject against HSV and treating, impeding, inhibiting, reducing the incidence of, or suppressing an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.
    Type: Application
    Filed: December 27, 2007
    Publication date: April 16, 2009
    Inventors: Harvey Friedman, Sita Awasthi, John Lubinski