Patents by Inventor Siu-Long Yao

Siu-Long Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF SUBJECTS WITH PLAQUE PSORIASIS OF THE SCALP
    Publication number: 20230303678
    Abstract: The disclosure relates to an anti-IL-23p19 antibody hum13B8-b or antigen binding fragment thereof and its use in the treatment of plaque psoriasis of the scalp.
    Type: Application
    Filed: January 24, 2023
    Publication date: September 28, 2023
    Applicant: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Judilyn FUENTES-DUCULAN, Tushar NISHANDAR, Rocco BALLERINI, Kristine NOGRALES, Siu-Long YAO
  • Methods for Treatment of Subjects with Psoriatic Arthritis
    Publication number: 20220298233
    Abstract: This disclosure relates to an anti-IL-23p19 antibody hum13B8-b or antigen binding fragment thereof and its use in the treatment of psoriatic arthritis.
    Type: Application
    Filed: April 15, 2020
    Publication date: September 22, 2022
    Inventors: Kirti Wardhaman Ganorkar, Atul Mathuradas Raut, Anil Raghavan, Siu-Long Yao
  • METHODS FOR TREATMENT OF POLYPOSIS
    Publication number: 20140050729
    Abstract: The present invention relates to method for treating medical disorders mediated by mutations in the APC gene by administering an IGF1R inhibitor. Such disorders include, for example, familial adenomatous polyposis (FAP).
    Type: Application
    Filed: May 24, 2013
    Publication date: February 20, 2014
    Inventor: Siu-Long Yao
  • Methods for treatment of polyposis
    Patent number: 8603465
    Abstract: The present invention relates to method for treating medical disorders mediated by mutations in the APC gene by administering an IGF1R inhibitor. Such disorders include, for example, familial adenomatous polyposis (FAP).
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: December 10, 2013
    Assignee: Merck Sharp & Dohme, Corp.
    Inventor: Siu-Long Yao
  • FDG-PET EVALUATION OF EWING'S SARCOMA SENSITIVITY
    Publication number: 20130243692
    Abstract: This invention relates to methods for evaluating the efficacy of an IGF1R inhibitor, such as an anti-IGF1R antibody, for the treatment of an Ewing's sarcoma tumor by determining the level of tumoral glucose metabolism. Tumoral glucose metabolism is determining at an early point in the treatment regimen by any of several methods known in the art including FDG-PET/CT scan.
    Type: Application
    Filed: May 20, 2013
    Publication date: September 19, 2013
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Brian Der-Hua Lu, Siu-Long Yao, Cynthia Seidel-Dugan, Yan Wang
  • FDG-pet evaluation of Ewing's sarcoma sensitivity
    Patent number: 8470297
    Abstract: This invention relates to methods for evaluating the efficacy of an IGF1R inhibitor, such as an anti-IGF1R antibody, for the treatment of an Ewing's sarcoma tumor by determining the level of tumoral glucose metabolism. Tumoral glucose metabolism is determining at an early point in the treatment regimen by any of several methods known in the art including FDG-PET/CT scan.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: June 25, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Brian DerHua Lu, Siu-Long Yao, Cynthia Seidel-Dugan, Yan Wang
  • METHODS OF TREATMENT
    Publication number: 20110262525
    Abstract: This invention relates to compositions and methods useful for treating various cancers. Therapeutic combinations and methods of use thereof are also covered in the present application.
    Type: Application
    Filed: December 11, 2007
    Publication date: October 27, 2011
    Applicant: SCHERING CORPORATION
    Inventors: Yan Wang, Chen Zong, Cynthia Seidel-Dugan, Yaolin Wang, Siu-Long Yao, Brian Der-Hua Lu, Mohamad H. Ladha
  • Sequential Administration of Chemotherapeutic Agents for Treatment of Cancer
    Publication number: 20110129456
    Abstract: The present invention relates to the sequential administration of a cytotoxic agent followed by an IGF1R antagonist (e.g., an antibody) for the treatment of hyperproliferative disorders including cancer.
    Type: Application
    Filed: May 4, 2009
    Publication date: June 2, 2011
    Inventors: Yaolin Wang, Yan Wang, Brian Der-Hua Lu, Ming Liu, Cynthia Seidel-Dugan, Siu-Long Yao
  • FORMULATION CONTAINING CYCLIN-DEPENDENT KINASE INHIBITING COMPOUND AND METHOD OF TREATING TUMORS USING THE SAME
    Publication number: 20100286038
    Abstract: This application discloses a novel formulation containing a 3-amino-4-substituted pyrazole derivative which has cyclin-dependent kinase inhibiting properties, and a method of treating tumors using the novel formulation.
    Type: Application
    Filed: September 16, 2008
    Publication date: November 11, 2010
    Inventors: Valentyn Antochshuk, Anita Dabbara, Paul Kirschmeier, David A. Parry, Mohammed Shameen, Siu-Long Yao
  • DISCONTINUOUS METHODS OF TREATING CANCER
    Publication number: 20100104661
    Abstract: Disclosed are methods of treating taxane sensitive tumors (i.e., cancers treatable with taxanes) using a taxane and the discontinuous dosing of lonafarnib.
    Type: Application
    Filed: October 23, 2007
    Publication date: April 29, 2010
    Inventors: Susan Arbuck, Paul Kirschmeier, Brian Long, Genevieve A. Menard, Siu-Long Yao
  • Method of treating cancer
    Publication number: 20040058857
    Abstract: The present invention relates to methods of treating cancer using a combination of a compound which is a PSA conjugate and a glucocorticoid, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least one PSA conjugate and at least one glucocorticoid. The invention also relates to methods of preparing such compositions.
    Type: Application
    Filed: May 29, 2003
    Publication date: March 25, 2004
    Inventor: Siu-Long Yao
  • Method of treating cancer
    Publication number: 20020042375
    Abstract: The present invention relates to methods of treating cancer using a combination of a compound which is a PSA conjugate and an NSAID compound, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least two therapeutic agents selected from a group consisting of a compound which is a PSA conjugate and an NSAID compound. The invention also relates to methods of preparing such compositions.
    Type: Application
    Filed: June 29, 2001
    Publication date: April 11, 2002
    Inventors: David C. Heimbrook, Siu-Long Yao