Patents by Inventor Siva N. Raman

Siva N. Raman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180280289
    Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Application
    Filed: June 7, 2018
    Publication date: October 4, 2018
    Inventors: Siva N. Raman, Jae Han Park, Thomas A. Diezi, Clifford J. Herman, Sunil K. Battu, Eric A. Burge
  • Publication number: 20180256493
    Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Inventors: Siva N. Raman, Jae Han Park, Thomas A. Diezi, Clifford J. Herman, Sunil K. Battu, Eric A. Burge
  • Patent number: 9993422
    Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Grant
    Filed: April 18, 2013
    Date of Patent: June 12, 2018
    Assignee: SpecGX LLC
    Inventors: Siva N. Raman, Jae Han Park, Thomas A. Diezi, Clifford J. Herman, Sunil K. Battu, Eric A. Burge
  • Publication number: 20180008532
    Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Application
    Filed: September 25, 2017
    Publication date: January 11, 2018
    Inventors: Siva N. Raman, Jae Han Park, Thomas A. Diezi, Clifford J. Herman, Sunil K. Battu, Eric A. Burge
  • Patent number: 9301918
    Abstract: The present disclosure provides an immediate release, abuse deterrent pharmaceutical solid dosage form comprising at least one functional score. In particular, the immediate release, abuse deterrent solid dosage form comprises at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 5, 2016
    Assignee: MALLINCKRODT LLC
    Inventors: Siva N. Raman, Jae Han Park, Sunil K. Battu, Eric A. Burge, David W. Bogan
  • Publication number: 20140271849
    Abstract: The present disclosure provides an immediate release, abuse deterrent pharmaceutical solid dosage form comprising at least one functional score. In particular, the immediate release, abuse deterrent solid dosage form comprises at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: Siva N. Raman, Jae Han Park, Sunil K. Battu, Eric A. Burge, David W. Bogan
  • Publication number: 20130280177
    Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight hydrophilic polymer, at least one high molecular weight hydrophilic polymer, and an effervescent system.
    Type: Application
    Filed: April 18, 2013
    Publication date: October 24, 2013
    Applicant: Mallinckrodt LLC
    Inventors: Siva N. Raman, Jae Han Park, Thomas A. Diezi, Clifford J. Herman
  • Publication number: 20130280176
    Abstract: The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate release of active ingredients and have abuse deterrent properties. The pharmaceutical compositions provided herein comprise at least one pharmaceutically active ingredient, at least one low molecular weight water-soluble polymer, at least one polyglycol, at least one polysaccharide, at least one clay mineral, and, optionally, an effervescent system.
    Type: Application
    Filed: April 18, 2013
    Publication date: October 24, 2013
    Applicant: Mallinckrodt LLC
    Inventors: Thomas A. Diezi, Jae Han Park, Siva N. Raman
  • Patent number: 8377480
    Abstract: There is disclosed a novel sustained release granular resin-pharmaceutical composition comprising an ion exchange resin complexed with a pharmaceutical material wherein said complex is embedded into and on the surface of a diffusion barrier material. There is also disclosed a novel process for preparing the granulated complex wherein an aqueous granulating vehicle is employed to form the complex and the granulated product, thereby avoiding the use of coatings and large amounts of organic solvents in the process.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: February 19, 2013
    Assignee: Hi-Tech Pharmacal Co., Inc.
    Inventors: Siva N. Raman, John P. Cunningham
  • Publication number: 20100316721
    Abstract: There is disclosed a novel sustained release granular resin-pharmaceutical composition comprising an ion exchange resin complexed with a pharmaceutical material wherein said complex is embedded into and on the surface of a diffusion barrier material. There is also disclosed a novel process for preparing the granulated complex wherein an aqueous granulating vehicle is employed to form the complex and the granulated product, thereby avoiding the use of coatings and large amounts of organic solvents in the process.
    Type: Application
    Filed: August 4, 2010
    Publication date: December 16, 2010
    Applicant: Mallinckrodt Inc.
    Inventors: Siva N. Raman, John P. Cunningham
  • Patent number: 7790201
    Abstract: There is disclosed a novel sustained release granular resin-pharmaceutical composition comprising an ion exchange resin complexed with a pharmaceutical material wherein said complex is embedded into and on the surface of a diffusion barrier material. There is also disclosed a novel process for preparing the granulated complex wherein an aqueous granulating vehicle is employed to form the complex and the granulated product, thereby avoiding the use of coatings and large amounts of organic solvents in the process.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: September 7, 2010
    Assignee: Mallinckrodt Inc.
    Inventors: Siva N. Raman, John P. Cunningham
  • Patent number: 5356635
    Abstract: A composition for the sustained release of a biologically active therapeutic agent wherein the matrix of the sustained release composition is composed of an amorphous carbohydrate glass matrix comprising a suitable carbohydrate and an agent which retards the recrystallization of the carbohydrate and a biologically active therapeutic agent and a water-insoluble wax dispersed throughout the matrix. Biologically active therapeutic agents which can be incorporated into the carbohydrate glass matrix include prolactin, growth hormones, serum albumins, growth factors or any biologically active fragment or recombinant form thereof.
    Type: Grant
    Filed: July 13, 1993
    Date of Patent: October 18, 1994
    Assignee: Mallinckrodt Veterinary, Inc.
    Inventors: Siva N. Raman, John P. Cunningham
  • Patent number: 5328697
    Abstract: The present invention relates to compositions for the sustained release of drugs and to methods for the production of such compositions. In one embodiment, somatotropin is layered onto non-pareil seeds, which, in turn are sprayed with a glycine solution. Next, a coating of a wax mixture is applied.
    Type: Grant
    Filed: February 10, 1992
    Date of Patent: July 12, 1994
    Assignee: Mallinckrodt Veterinary, Inc.
    Inventors: Siva N. Raman, Matthew W. Gray, Rodger L. Smith