Patents by Inventor Siva Rama K. Nutalapati

Siva Rama K. Nutalapati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methylnaltrexone nasal formulations, methods of making, and use thereof
    Patent number: 11207317
    Abstract: Methylnaltrexone nasal formulations are disclosed which provide improved bioavailability over oral dosage forms and improved patient compliance over injectable dosage forms. Also disclosed are methods of making the nasal formulations and methods of using, specifically to treat the side effects of opioid drug use, such as constipation, and other indications.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: December 28, 2021
    Assignee: APTAPHARMA INC.
    Inventor: Siva Rama K. Nutalapati
  • METHYLNALTREXONE NASAL FORMULATIONS, METHODS OF MAKING, AND USE THEREOF
    Publication number: 20200054626
    Abstract: Methylnaltrexone nasal formulations are discloses which provide improved bioavailability over oral dosage forms and improved patient compliance over injectable dosage forms. Also disclosed are methods of making the nasal formulations and methods of using, specifically to treat the side effects of opioid drug use, such as constipation, and other indications.
    Type: Application
    Filed: October 24, 2019
    Publication date: February 20, 2020
    Inventor: Siva Rama K. Nutalapati
  • Methylnaltrexone nasal formulations, methods of making, and use thereof
    Patent number: 10485798
    Abstract: Methylnaltrexone nasal formulations are discloses which provide improved bioavailability over oral dosage forms and improved patient compliance over injectable dosage forms. Also disclosed are methods of making the nasal formulations and methods of using, specifically to treat the side effects of opioid drug use, such as constipation, and other indications.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: November 26, 2019
    Assignee: APTAPHARMA INC.
    Inventor: Siva Rama K. Nutalapati
  • Antihistamine compositions, combinations, and use thereof
    Patent number: 10426724
    Abstract: Combinations of a first generation antihistamine for a quick onset with a maintenance dosage amount of a second or third generation antihistamine, along with an additional active agent such as a decongestant, a cough suppressant (an antitussive), a leukotriene receptor antagonist, a 5-lipoxygenase inhibitor, a bronchodilator, an expectorant, or a combination thereof, are disclosed. Methods of using such combinations by concomitant administration, either in the form of a single composition or multiple compositions, are further disclosed.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: October 1, 2019
    Assignee: APTAPHARMA INC.
    Inventors: Siva Rama K. Nutalapati, Prahlad Patel, Nisha Sureshbhai Patel
  • ANTIHISTAMINE COMPOSITIONS, COMBINATIONS, AND USE THEREOF
    Publication number: 20180338913
    Abstract: Combinations of a first generation antihistamine for a quick onset with a maintenance dosage amount of a second or third generation antihistamine, along with an additional active agent such as a decongestant, a cough suppressant (an antitussive), a leukotriene receptor antagonist, a 5-lipoxygenase inhibitor, a bronchodilator, an expectorant, or a combination thereof, are disclosed. Methods of using such combinations by concomitant administration, either in the form of a single composition or multiple compositions, are further disclosed.
    Type: Application
    Filed: August 2, 2018
    Publication date: November 29, 2018
    Inventors: Siva Rama K. Nutalapati, Prahlad Patel, Nisha Sureshbhai Patel
  • Antihistamine compositions, combinations, and use thereof
    Patent number: 10064820
    Abstract: Combinations of a first generation antihistamine for a quick onset with a maintenance dosage amount of a second or third generation antihistamine, along with an additional active agent such as a decongestant, a cough suppressant (an antitussive), a leukotriene receptor antagonist, a 5-lipoxygenase inhibitor, a bronchodilator, an expectorant, or a combination thereof, are disclosed. Methods of using such combinations by concomitant administration, either in the form of a single composition or multiple compositions, are further disclosed.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: September 4, 2018
    Assignee: APTAPHARMA INC.
    Inventors: Siva Rama K. Nutalapati, Prahlad Patel, Nisha Sureshbhai Patel
  • ANTIHISTAMINE COMPOSITIONS, COMBINATIONS, AND USE THEREOF
    Publication number: 20180092837
    Abstract: Combinations of a first generation antihistamine for a quick onset with a maintenance dosage amount of a second or third generation antihistamine, along with an additional active agent such as a decongestant, a cough suppressant (an antitussive), a leukotriene receptor antagonist, a 5-lipoxygenase inhibitor, a bronchodilator, an expectorant, or a combination thereof, are disclosed. Methods of using such combinations by concomitant administration, either in the form of a single composition or multiple compositions, are further disclosed.
    Type: Application
    Filed: September 30, 2016
    Publication date: April 5, 2018
    Inventors: Siva Rama K. Nutalapati, Prahlad Patel, Nisha Sureshbhai Patel
  • METHODS OF ADMINISTERING ANTIHISTAMINES
    Publication number: 20160120811
    Abstract: Methods of using combinations of antihistamines by administering an attenuated dosage amount of a first generation antihistamine for a quick onset concomitantly with a maintenance dosage amount of a second or third generation antihistamine are disclosed.
    Type: Application
    Filed: January 13, 2016
    Publication date: May 5, 2016
    Inventor: Siva Rama K. Nutalapati
  • Methods of administering antihistamines
    Patent number: 9265757
    Abstract: Methods of using combinations of antihistamines by administering an attenuated dosage amount of a first generation antihistamine for a quick onset concomitantly with a maintenance dosage amount of a second or third generation antihistamine are disclosed.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: February 23, 2016
    Assignee: APTAPHARMA INC.
    Inventor: Siva Rama K. Nutalapati
  • METHYLNALTREXONE NASAL FORMULATIONS, METHODS OF MAKING, AND USE THEREOF
    Publication number: 20140057934
    Abstract: Methylnaltrexone nasal formulations are discloses which provide improved bioavailability over oral dosage forms and improved patient compliance over injectable dosage forms. Also disclosed are methods of making the nasal formulations and methods of using, specifically to treat the side effects of opioid drug use, such as constipation, and other indications.
    Type: Application
    Filed: August 21, 2013
    Publication date: February 27, 2014
    Applicant: AptaPharma Inc.
    Inventor: Siva Rama K. Nutalapati
  • METHODS OF ADMINISTERING ANTIHISTAMINES
    Publication number: 20130053399
    Abstract: Methods of using combinations of antihistamines by administering an attenuated dosage amount of a first generation antihistamine for a quick onset concomitantly with a maintenance dosage amount of a second or third generation antihistamine are disclosed.
    Type: Application
    Filed: July 19, 2012
    Publication date: February 28, 2013
    Inventor: Siva Rama K. Nutalapati
  • QUININE FORMULATIONS, METHOD OF MAKING, AND METHOD OF USE THEREOF
    Publication number: 20120183605
    Abstract: Disclosed herein are quinine formulations and methods of using quinine formulations. Specifically disclosed herein are solid oral dosage forms which can be administered as a capsule or tablet, or alternatively as a sprinkle form with the patient experiencing little or no bitter taste. The dosage forms provide immediate release in vitro and in vivo.
    Type: Application
    Filed: September 14, 2011
    Publication date: July 19, 2012
    Inventors: Kristin Arnold, Matthew W. Davis, Suman Wason, Siva Rama K. Nutalapati
  • QUININE FORMULATIONS, METHOD OF MAKING, AND METHOD OF USE THEREOF
    Publication number: 20110150992
    Abstract: Disclosed herein are quinine formulations and methods of using quinine formulations. Specifically disclosed herein are solid oral dosage forms which can be administered as a capsule or tablet, or alternatively as a sprinkle form with the patient experiencing little or no bitter taste. The dosage forms provide immediate release in vitro and in vivo.
    Type: Application
    Filed: December 17, 2010
    Publication date: June 23, 2011
    Inventors: Kristin Arnold, Matthew W. Davis, Suman Wason, Siva Rama K. Nutalapati
  • QUININE FORMULATIONS, METHOD OF MAKING, AND METHO OF USE THEREOF
    Publication number: 20110150986
    Abstract: Disclosed herein are quinine formulations and methods of using quinine formulations. Specifically disclosed herein are solid oral dosage forms which can be administered as a capsule or tablet, or alternatively as a sprinkle form with the patient experiencing little or no bitter taste. The dosage forms provide immediate release in vitro and in vivo.
    Type: Application
    Filed: March 25, 2010
    Publication date: June 23, 2011
    Inventors: Kristin Arnold, Matthew W. Davis, Suman Wason, Siva Rama K. Nutalapati
  • CONTROLLED-RELEASE FORMULATIONS
    Publication number: 20100183717
    Abstract: Disclosed herein are controlled-release formulations of a core comprising a core active agent (e.g., alfuzosin) and a wax excipient substantially coated with an extended-release coating.
    Type: Application
    Filed: January 15, 2010
    Publication date: July 22, 2010
    Inventors: Kristin Arnold, Zhongshui Yu, Siva Rama K. Nutalapati
  • CONTROLLED-RELEASE FORMULATIONS
    Publication number: 20100172979
    Abstract: Disclosed herein are controlled-release formulations containing a core comprising a core active agent (e.g., levetiracetam) and a wax excipient, where the core is substantially coated with an extended-release coating.
    Type: Application
    Filed: December 18, 2009
    Publication date: July 8, 2010
    Inventors: Zhongshui Yu, Kristin Arnold, Siva Rama K. Nutalapati
  • CONTROLLED-RELEASE FORMULATIONS
    Publication number: 20100159009
    Abstract: Disclosed herein are extended-release levetiracetam formulations having a matrix comprising levetiracetam and a hydrophobic excipient or an acrylic polymer excipient.
    Type: Application
    Filed: December 18, 2009
    Publication date: June 24, 2010
    Inventors: Zhongshui Yu, Kristin Arnold, Siva Rama K. Nutalapati
  • CARVEDILOL FORMS, COMPOSITIONS, AND METHODS OF PREPARATION THEREOF
    Publication number: 20090263478
    Abstract: Disclosed are amorphous carvedilol salt forms, controlled-release carvedilol compositions, and methods of preparing the forms and compositions.
    Type: Application
    Filed: July 9, 2009
    Publication date: October 22, 2009
    Inventors: Kristin Arnold, David F. Erkoboni, Rakeshkumar K. Lad, Siva Rama K. Nutalapati, Zhongshui Yu
  • CARVEDILOL FORMS, COMPOSITIONS, AND METHODS OF PREPARATION THEREOF
    Publication number: 20080292695
    Abstract: Disclosed are amorphous carvedilol salt forms, controlled-release carvedilol compositions, and methods of preparing the forms and compositions.
    Type: Application
    Filed: December 3, 2007
    Publication date: November 27, 2008
    Inventors: Kristin Arnold, E. Brendan Magrab, David F. Erkoboni, Zhongshui Yu, Siva Rama K. Nutalapati, Rakeshkumar K. Lad