Patents by Inventor Siva Rama Prasad Vellanki

Siva Rama Prasad Vellanki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline Darunavir
    Patent number: 9216990
    Abstract: The present invention relates to a non-solvated crystalline Darunavir, process for its preparation and pharmaceutical composition comprising it. The present invention also relates to a process for the preparation of amorphous Darunavir from a non-solvated crystalline Darunavir.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: December 22, 2015
    Assignee: Mylan Labs Limited
    Inventors: Siva Rama Prasad Vellanki, Arabinda Sahu, Naveen Kumar Phadhuri, Ravindrababu Kilaru
  • Crystalline Darunavir
    Publication number: 20140350270
    Abstract: The present invention relates to a non-solvated crystalline Darunavir, process for its preparation and pharmaceutical composition comprising it. The present invention also relates to a process for the preparation of amorphous Darunavir from a non-solvated crystalline Darunavir.
    Type: Application
    Filed: December 5, 2012
    Publication date: November 27, 2014
    Applicant: Mylan Laboratores LTD
    Inventors: Siva Rama Prasad Vellanki, Arabinda Sahu, Naveen Kumar Phadhuri, Ravindrababu Kilaru
  • Process for the preparation of tenofovir disoproxil fumarate
    Patent number: 8759515
    Abstract: The present invention relates to an improved process for the preparation of Tenofovir Disoproxil and its pharmaceutically acceptable salts comprising the steps of: a) esterifying Tenofovir with chloromethyl isopropyl carbonate in presence of a base, phase transfer catalyst and optionally dehydrating agent, in a suitable solvent; b) optionally purifying Tenofovir Disoproxil; and c) converting of Tenofovir Disoproxil into its pharmaceutically acceptable salts. The present invention further relates to a process for the preparation of Tenofovir by reacting 1-(6-amino-purin-9-yl)-propan-2-ol with toluene-4-sulfonic acid diethoxy phosphoryl methyl ester in presence of a base in a non-polar solvent medium followed by hydrolysis.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: June 24, 2014
    Assignee: Mylan Laboratories Limited
    Inventors: Debashish Datta, Siva Rama Prasad Vellanki, Arabinda Sahu, Raja Babu Balusu, Mastan Rao Ravi, Hari Babu Nandipati, Shankar Rama, Lakshmana Rao Vadali, Srikanth Sarat Chandra Gorantla, Srinivasa Rao Dasari, Nagaraju Mittapelly
  • Process for the preparation of darunavir
    Patent number: 8703980
    Abstract: A process for the preparation of Darunavir comprises the reacting of 4-amino-N-(2R, 3S) (3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-benzenesulfonamide with (3R, 3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivative in N-methyl-2-pyrrolidinone and isolating the resulting Darunavir. The process yields Darunavir with a very low level of the difuranyl impurity.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: April 22, 2014
    Inventors: Siva Rama Prasad Vellanki, Arabinda Sahu, Aravind Kumar Katukuri, Vikram Vanama, Satishbabu Kothari, Venkata Suryanarayana Ponnekanti, Debashish Datta
  • PROCESS FOR THE PREPARATION OF 2-ARYLTHIAZOLE DERIVATIVES
    Publication number: 20130303780
    Abstract: The present invention relates an improved process for the preparation of 2-arylthiazole derivatives which are intermediates of Febuxostat and further conversion to Febuxostat or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: November 3, 2011
    Publication date: November 14, 2013
    Inventors: Siva Rama Prasad Vellanki, Arabinda Sahu, Satyanarayana Raavi, Ravi Nuchu, Ramesh Dandala
  • NOVEL PROCESS FOR THE PREPARATION OF (3S)-TETRAHYDROFURAN-3-YL (IS, 2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-(PHOSPHONOOXY) PROPYLCARBAMATE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
    Publication number: 20130211108
    Abstract: The present invention relates to a novel process for the preparation of Fosamprenavir or its pharmaceutically acceptable salts thereof by using novel intermediates.
    Type: Application
    Filed: June 17, 2011
    Publication date: August 15, 2013
    Inventors: Siva Rama Prasad Vellanki, Madhu Murthy Nadella, Rajendra Reddy Mulamalla, Siva Koteswara Rao Prathi, Ravathi Srinivas Rambhotla, Siva Reddy Arumalla, Debashish Datta
  • PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL FUMARATE
    Publication number: 20130005969
    Abstract: The present invention relates to an improved process for the preparation of Tenofovir Disoproxil and its pharmaceutically acceptable salts comprising the steps of: a) esterifying Tenofovir with chloromethyl isopropyl carbonate in presence of a base, phase transfer catalyst and optionally dehydrating agent, in a suitable solvent; b) optionally purifying Tenofovir Disoproxil; and c) converting of Tenofovir Disoproxil into its pharmaceutically acceptable salts. The present invention further relates to a process for the preparation of Tenofovir by reacting 1-(6-amino-purin-9-yl)-propan-2-ol with toluene-4-sulfonic acid diethoxy phosphoryl methyl ester in presence of a base in a non-polar solvent medium followed by hydrolysis.
    Type: Application
    Filed: March 11, 2011
    Publication date: January 3, 2013
    Inventors: Debashish Datta, Siva Rama Prasad Vellanki, Arabinda Sahu, Raja Babu Balusu, Mastan Rao Ravi, Hari Babu Nandipati, Shankar Rama, Lakshmana Rao Vadali, Srikanth Sarat Chandra Gorantla, Srinivasa Rao Dasari, Nagaraju Mittapelly
  • PROCESS FOR THE PREPARATION OF DARUNAVIR
    Publication number: 20120251826
    Abstract: A process for the preparation of Darunavir comprises the reacting of 4-amino-N-(2R,3S) (3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-benzenesulfonamide with (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivative in N-methyl-2-pyrrolidinone and isolating the resulting Darunavir. The process yields Darunavir with a very low level of the difuranyl impurity.
    Type: Application
    Filed: September 16, 2010
    Publication date: October 4, 2012
    Inventors: Siva Rama Prasad Vellanki, Arabinda Sahu, Aravind Kumar Katukuri, Vikram Vanama, Satishbabu Kothari, Venkata Suryanarayana Ponnekanti, Debashish Datta
  • Process for the preparation of Tenofovir
    Patent number: 8049009
    Abstract: The present invention relates to novel Tenofovir disoproxil hemifumarate salt, which is prepared by dealkylation of Phosphonate esters by using mineral acids followed by esterification and crystallization to give crystalline Tenofovir disoproxil. The Tenofovir disoproxil is further converted to fumarate salts with improved yield.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: November 1, 2011
    Assignee: Matrix Laboratories Ltd.
    Inventors: Uma Maheswer Rao Vasireddy, Siva Rama Prasad Vellanki, Raja Babu Balusu, Naga Durga Rao Bandi, Pavan Kumar Jujjavarapu, Sambasiva Rao Ginjupalli, Rama Krishna Pilli
  • PROCESS FOR THE PREPARTION OF TENOFOVIR
    Publication number: 20090286981
    Abstract: The present invention relates to novel Tenofovir disoproxil hemifumarate salt, which is prepared by dealkylation of Phosphonate esters by using mineral acids followed by esterification and crystallization to give crystalline Tenofovir disoproxil. The Tenofovir disoproxil is further converted to fumarate salts with improved yield.
    Type: Application
    Filed: January 12, 2009
    Publication date: November 19, 2009
    Inventors: Uma Maheswer Rao Vasireddy, Siva Rama Prasad Vellanki, Raja Babu Balusu, Naga Durga Rao Bandi, Pavan Kumar Jujjavarapu, Sambasiva Rao Ginjupalli, Rama Krishna Pilli