Patents by Inventor Siva Ramarao Kakani

Siva Ramarao Kakani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11661396
    Abstract: The present invention provides novel crystalline forms of zuclomiphene citrate. Specific crystalline forms provided by the present invention include zuclomiphene citrate Forms APO-I, APO-II, APO-III, and APO-IV. Also provided are pharmaceutical compositions including the zuclomiphene citrate crystalline forms, processes for the preparation thereof and the use of these forms in the treatment of a disorder selected from the group including osteoporosis, bone fractures, loss of bone mineral density (BMD) and hot flashes in a subject suffering therefrom.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: May 30, 2023
    Assignee: Apotex Inc.
    Inventors: Fabio E. S. Souza, Mohammed Abdul Raheem, Yajun Zhao, Siva Ramarao Kakani, Minh T. N. Nguyen, Alexander J. Stirk, Allan W. Rey, Stuart P. Green
  • Patent number: 11440871
    Abstract: The present invention provides zuclomiphene salts, zuclomiphene binaphthyl hydrogen phosphate salt (1-A)·(BPA) and zuclomiphene oxalate salt (1-A)·(OXL), crystalline forms thereof and processes for the preparation thereof.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: September 13, 2022
    Assignee: Apotex Inc.
    Inventors: Mohammed Abdul Raheem, Siva Ramarao Kakani, Minh T. N. Nguyen, Yajun Zhao, Stuart P. Green, Fabio E. S. Souza, Alexander J. Stirk, Fatemeh Mohammadpourmir
  • Publication number: 20210221767
    Abstract: The present invention provides novel crystalline forms of zuclomiphene citrate. Specific crystalline forms provided by the present invention include zuclomiphene citrate Forms APO-I, APO-II, APO-III, and APO-IV. Also provided are pharmaceutical compositions including the zuclomiphene citrate crystalline forms, processes for the preparation thereof and the use of these forms in the treatment of a disorder selected from the group including osteoporosis, bone fractures, loss of bone mineral density (BMD) and hot flashes in a subject suffering therefrom.
    Type: Application
    Filed: January 21, 2021
    Publication date: July 22, 2021
    Inventors: Fabio E. S. Souza, Mohammed Abdul Raheem, Yajun Zhao, Siva Ramarao Kakani, Minh T. N. Nguyen, Alexander J. Stirk, Allan W. Rey, Stuart P. Green
  • Publication number: 20210147338
    Abstract: The present invention provides zuclomiphene salts, zuclomiphene binaphthyl hydrogen phosphate salt (1-A)?(BPA) and zuclomiphene oxalate salt (1-A)?(OXL), crystalline forms thereof and processes for the preparation thereof.
    Type: Application
    Filed: November 11, 2020
    Publication date: May 20, 2021
    Inventors: Mohammed Abdul Raheem, Siva Ramarao Kakani, Minh T. N. Nguyen, Yajun Zhao, Stuart P. Green, Fabio E.S. Souza, Alexander J. Stirk, Fatemeh Mohammadpourmir