Patents by Inventor Siwei GUO

Siwei GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250197440
    Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist.
    Type: Application
    Filed: March 7, 2025
    Publication date: June 19, 2025
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Michael Anthony Schmidt, Bin Zheng, Benjamin M. Cohen, Amanda J. Rogers, Changxia Yuan, Jason J. Zhu, Chao Hang, Daniel S. Treitler, Adam Joseph Freitag, Geoffrey Eugene Purdum, Miao Yu, Melda Sezen Edmonds, Siwei Guo
  • Patent number: 12269840
    Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: April 8, 2025
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Michael Anthony Schmidt, Bin Zheng, Benjamin M. Cohen, Amanda J. Rogers, Changxia Yuan, Jason J. Zhu, Chao Hang, Daniel S. Treitler, Adam Joseph Freitag, Geoffrey Eugene Purdum, Miao Yu, Melda Sezen Edmonds, Siwei Guo
  • Publication number: 20220064205
    Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.
    Type: Application
    Filed: December 3, 2019
    Publication date: March 3, 2022
    Inventors: Michael Anthony Schmidt, Bin Zheng Kendall Park, Benjamin M. Cohen, Amanda J. Rogers, Changxia Yuan Warren, Jason J. Zhu, Chao Hang, Daniel S. Treitler, Adam Josep Freitag, Geoffrey Eugene Purdum, Miao Yu, Melda Sezen Edmonds, Siwei Guo
  • Patent number: 10786756
    Abstract: The process involves the use of two rotary valves to implement Varicol operation of a simulated moving bed apparatus to separate a product from at least one multicomponent feed. In a particular embodiment, paraxylene is separated from a mixture of C8 aromatic hydrocarbons. The use of the Varicol process further enhances the separation of the desired product and provides flexibility with a simulated moving bed apparatus using dual rotary valves.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: September 29, 2020
    Assignees: EXXONMOBIL CHEMICAL PATENTS INC., GEORGIA TECH RESEARCH CORPORATION
    Inventors: Michael W. Weber, Siwei Guo, Yoshiaki Kawajiri, Jason Bentley, Gaurav Agrawal, Michael Salciccioli, Dana L. Pilliod
  • Patent number: 10392324
    Abstract: A process to separate paraxylene from a mixture of paraxylene, metaxylene, orthoxylene, and ethylbenzene in a commercial simulated moving bed apparatus in a reduced number of beds is provided, allowing an additional separation to be conducted in the remaining beds. This additional separation may separate another xylene isomer, ethylbenzene, or a non-aromatic C8+ hydrocarbon from the raffinate stream produced by the first separation. A PowerFeed process is used to recover paraxylene in a first adsorption zone containing 8-16 beds of a conventional 24-bed simulated moving bed adsorption apparatus, and then a second separation may be conducted in a second adsorption zone containing the remaining beds.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: August 27, 2019
    Assignees: EXXONMOBIL CHEMICAL PATENTS INC., GEORGIA TECH RESEARCH CORPORATION
    Inventors: Michael W. Weber, Yoshiaki Kawajiri, Michael Salciccioli, John R. Porter, Gaurav Agrawal, Dana L. Pilliod, Siwei Guo, Jason Bentley
  • Publication number: 20190184311
    Abstract: The process involves the use of two rotary valves to implement Varicol operation of a simulated moving bed apparatus to separate a product from at least one multicomponent feed. In a particular embodiment, paraxylene is separated from a mixture of C8 aromatic hydrocarbons. The use of the Varicol process further enhances the separation of the desired product and provides flexibility with a simulated moving bed apparatus using dual rotary valves.
    Type: Application
    Filed: February 9, 2017
    Publication date: June 20, 2019
    Inventors: Michael W. WEBER, Siwei GUO, Yoshiaki KAWAJIRI, Jason BENTLEY, Gaurav AGRAWAL, Michael SALCICCIOLI, Dana L. PILLIOD
  • Publication number: 20190185394
    Abstract: A process to separate paraxylene from a mixture of paraxylene, metaxylene, orthoxylene, and ethylbenzene in a commercial simulated moving bed apparatus in a reduced number of beds is provided, allowing an additional separation to be conducted in the remaining beds. This additional separation may separate another xylene isomer, ethylbenzene, or a non-aromatic C8+ hydrocarbon from the raffinate stream produced by the first separation. A PowerFeed process is used to recover paraxylene in a first adsorption zone containing 8-16 beds of a conventional 24-bed simulated moving bed adsorption apparatus, and then a second separation may be conducted in a second adsorption zone containing the remaining beds.
    Type: Application
    Filed: May 17, 2017
    Publication date: June 20, 2019
    Inventors: Michael W. WEBER, Yoshiaki KAWAJIRI, Michael SALCICCIOLI, John R. PORTER, Gaurav AGRAWAL, Dana L. PILLIOD, Siwei GUO, Jason BENTLEY
  • Patent number: 10093598
    Abstract: A process is described for separating paraxylene from a multicomponent fluid mixture of C8 aromatics. A mixture of C8 aromatics is fed to a simulated moving-bed adsorptive apparatus. The location of the feed to the apparatus is moved at set intervals. The rate of flow of feed to the apparatus is varied during each interval to enhance the separation of paraxylene from the multicomponent mixture.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: October 9, 2018
    Assignees: EXXONMOBIL CHEMICAL PATENTS INC., GEORGIA TECH RESEARCH CORPORATION
    Inventors: John D. Ou, Jeevan S. Abichandani, Yoshiaki Kawajiri, Siwei Guo
  • Publication number: 20180009729
    Abstract: A process is described for separating paraxylene from a multicomponent fluid mixture of C8 aromatics. A mixture of C8 aromatics is fed to a simulated moving-bed adsorptive apparatus. The location of the feed to the apparatus is moved at set intervals. The rate of flow of feed to the apparatus is varied during each interval to enhance the separation of paraxylene from the multicomponent mixture.
    Type: Application
    Filed: December 28, 2015
    Publication date: January 11, 2018
    Inventors: John D. OU, Jeevan S. ABICHANDANI, Yoshiaki KAWAJIRI, Siwei GUO