Patents by Inventor Siyuan Xia

Siyuan Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dehydroacetic acid (DHAA) and derivative for uses in treating cancer
    Patent number: 10792274
    Abstract: This disclosure relates to methods of managing or treating cancer with agents that lower circulating acetoacetate levels, such as hypolipidemic agents, or other agents that antagonize acetoacetate-BRAF V600 mutant binding to attenuate BRAF V600 mutant tumor growth. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of an agent to a subject in need thereof, wherein the agent is dehydroacetic acid, derivative, prodrug, or salt thereof.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: October 6, 2020
    Assignees: Emory University, The United States Government as Represented by the Department of Veterans Affairs
    Inventors: Jing Chen, Jack Arbiser, Brian Pollack, Siyuan Xia
  • Dehydroacetic Acid (DHAA) and Derivative for Uses in Treating Cancer
    Publication number: 20200000764
    Abstract: This disclosure relates to methods of managing or treating cancer with agents that lower circulating acetoacetate levels, such as hypolipidemic agents, or other agents that antagonize acetoacetate-BRAF V600 mutant binding to attenuate BRAF V600 mutant tumor growth. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of an agent to a subject in need thereof, wherein the agent is dehydroacetic acid, derivative, prodrug, or salt thereof.
    Type: Application
    Filed: April 17, 2019
    Publication date: January 2, 2020
    Inventors: Jing Chen, Jack Arbiser, Brian Pollack, Siyuan Xia