Abstract: Ironized viral particles such as ironized adeno-associated viral particles, which may carry a photosensitizer such as a KillerRed protein, and uses thereof in light-triggered virotherapy against tumor.

Abstract: A method for releasing viruses includes the steps of: preparing a first negatively charged complex, comprising a plurality of viruses, a plurality of polyethyleneimine particles, and a copolymer; transferring the complex to an acidic region, thereby transforming the complex into a positively charged complex to release a portion of the viruses in the acidic region; and transferring the complex to a non-acidic region, thereby transforming the positively charged complex into a negatively charged complex. One embodiment of the copolymer has the following chemical formula: wherein R1 represents aliphatic compounds or aromatic compounds, and R2 includes at least one negatively charged group.

Abstract: A method for preparing a hydrogel includes the steps of injecting a precursor with at least two alkene groups into a predetermined portion, injecting at least one specie into the predetermined portion, and performing an X-ray irradiation on the predetermined portion to induce a polymerization reaction of the precursor to form a porous hydrogel with the specie embedded inside the porous hydrogel. In one embodiment of the present invention, the specie is selected from the group consisting of nucleic acid and adhesion agent.