Patents by Inventor Skevi Kyriakou

Skevi Kyriakou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Target-enriched multiplexed parallel analysis for assessment of risk for genetic conditions
    Patent number: 11879157
    Abstract: The invention provides methods for assessment of risk for genetic conditions using target-enriched multiplexed parallel analysis, for example fetal risk for genetic conditions in prenatal testing. The methods of the invention utilize Target Capture Sequences (TACS) to thereby enrich for target sequences of interest, followed by massive parallel sequencing and statistical analysis of the enriched population. The methods of the disclosure can be used to determine carrier status of inheritable genetic abnormalities associated with genetic conditions and from this information the fetal risk of inheriting the genetic condition can be determined. Kits for carrying out the methods of the invention are also provided.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: January 23, 2024
    Assignee: NIPD GENETICS PUBLIC COMPANY LIMITED
    Inventors: George Koumbaris, Marios Ioannides, Kyriakos Tsangaras, Charalambos Loizides, Michalis Nicolaou, Skevi Kyriakou, Philippos Patsalis, Elena Kypri
  • TARGET-ENRICHED MULTIPLEXED PARALLEL ANALYSIS FOR ASSESSMENT OF RISK FOR GENETIC CONDITIONS
    Publication number: 20210147937
    Abstract: The invention provides methods for assessment of risk for genetic conditions using target-enriched multiplexed parallel analysis, for example fetal risk for genetic conditions in prenatal testing. The methods of the invention utilize Target Capture Sequences (TACS) to thereby enrich for target sequences of interest, followed by massive parallel sequencing and statistical analysis of the enriched population. The methods of the disclosure can be used to determine carrier status of inheritable genetic abnormalities associated with genetic conditions and from this information the fetal risk of inheriting the genetic condition can be determined. Kits for carrying out the methods of the invention are also provided.
    Type: Application
    Filed: July 6, 2018
    Publication date: May 20, 2021
    Inventors: George Koumbaris, Marios loannides, Kyriakos Tsangaras, Charalambos Loizides, Michalis Nicolaou, Skevi Kyriakou, Philippos Patsalis, Elena Kypri