Patents by Inventor Slawomir Antoszczyk
Slawomir Antoszczyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11891594Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: GrantFiled: October 29, 2021Date of Patent: February 6, 2024Assignee: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Patent number: 11739364Abstract: Systems and methods are provided herein for rapid detection, separation, purification, and quantification of viral particles in a sample. According to some embodiments, a microfluidic device is provided for receiving the sample which may contain viral particles. An electrode of the microfluidic device may be used to generate dielectrophoretic (DEP) and/or electroosmotic (EO) forces acting on the sample. The applied DEP and/or EO forces may immobilize components of the sample on the surface of the electrode, may aggregate viral particles of the sample in one region of the microfluidic device, and may separate other components of the sample from the viral particles. The techniques may be performed rapidly, for example, in eight hours or less, and may not affect infectivity of the viral particles. In some embodiments, the sample may be labeled to enhance a response of one or more of the sample components to the DEP and/or EO forces.Type: GrantFiled: April 23, 2021Date of Patent: August 29, 2023Assignee: FLUID-SCREEN, INC.Inventors: Slawomir Antoszczyk, Monika Weber, Robert Weber
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Patent number: 11359212Abstract: Compositions for expressing a polypeptide within a target organ, the composition comprising a delivery particle, and at least a first mRNA sequence complexed with, encapsulated by, or otherwise associated with the delivery particle, wherein the mRNA sequence comprises at least one coding sequence which codes for at least one polypeptide, at least a first untranslated region (UTR) sequence, and at least one micro-RNA (miRNA) binding site sequence, wherein the miRNA binding site sequence is located within, immediately 5? to, or immediately 3? to, the first UTR sequence; and wherein the miRNA binding site sequence provides for differential expression of the coding sequence between first and second cell types comprised within the target organ.Type: GrantFiled: March 6, 2020Date of Patent: June 14, 2022Assignee: Combined Therapeutics, Inc.Inventors: Romain Micol, Slawomir Antoszczyk
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Publication number: 20220056389Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: November 5, 2021Publication date: February 24, 2022Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20220056388Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: November 3, 2021Publication date: February 24, 2022Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20220056390Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: November 5, 2021Publication date: February 24, 2022Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20220049202Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: October 29, 2021Publication date: February 17, 2022Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Patent number: 11203734Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: GrantFiled: December 31, 2020Date of Patent: December 21, 2021Assignee: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Patent number: 11198844Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: GrantFiled: December 31, 2020Date of Patent: December 14, 2021Assignee: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Patent number: 11198843Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: GrantFiled: December 31, 2020Date of Patent: December 14, 2021Assignee: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Patent number: 11193101Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: GrantFiled: December 31, 2020Date of Patent: December 7, 2021Assignee: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20210238648Abstract: Systems and methods are provided herein for rapid detection, separation, purification, and quantification of viral particles in a sample. According to some embodiments, a microfluidic device is provided for receiving the sample which may contain viral particles. An electrode of the microfluidic device may be used to generate dielectrophoretic (DEP) and/or electroosmotic (EO) forces acting on the sample. The applied DEP and/or EO forces may immobilize components of the sample on the surface of the electrode, may aggregate viral particles of the sample in one region of the microfluidic device, and may separate other components of the sample from the viral particles. The techniques may be performed rapidly, for example, in eight hours or less, and may not affect infectivity of the viral particles. In some embodiments, the sample may be labeled to enhance a response of one or more of the sample components to the DEP and/or EO forces.Type: ApplicationFiled: April 23, 2021Publication date: August 5, 2021Applicant: Fluid-Screen, Inc.Inventors: Slawomir Antoszczyk, Monika Weber, Robert Weber
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Patent number: 11072810Abstract: Systems and methods are provided herein for rapid detection, separation, purification, and quantification of viral particles in a sample. According to some embodiments, a microfluidic device is provided for receiving the sample which may contain viral particles. An electrode of the microfluidic device may be used to generate dielectrophoretic (DEP) and/or electroosmotic (EO) forces acting on the sample. The applied DEP and/or EO forces may immobilize components of the sample on the surface of the electrode, may aggregate viral particles of the sample in one region of the microfluidic device, and may separate other components of the sample from the viral particles. The techniques may be performed rapidly, for example, in eight hours or less, and may not affect infectivity of the viral particles. In some embodiments, the sample may be labeled to enhance a response of one or more of the sample components to the DEP and/or EO forces.Type: GrantFiled: November 12, 2020Date of Patent: July 27, 2021Assignee: Fluid-Screen, Inc.Inventors: Slawomir Antoszczyk, Monika Weber, Robert Weber
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Publication number: 20210146359Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: December 31, 2020Publication date: May 20, 2021Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20210146358Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: December 31, 2020Publication date: May 20, 2021Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20210139831Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: December 31, 2020Publication date: May 13, 2021Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20210138466Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.Type: ApplicationFiled: December 31, 2020Publication date: May 13, 2021Applicant: Fluid-Screen, Inc.Inventors: Monika Weber, Slawomir Antoszczyk, Robert Weber
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Publication number: 20210139944Abstract: Systems and methods are provided herein for rapid detection, separation, purification, and quantification of viral particles in a sample. According to some embodiments, a microfluidic device is provided for receiving the sample which may contain viral particles. An electrode of the microfluidic device may be used to generate dielectrophoretic (DEP) and/or electroosmotic (EO) forces acting on the sample. The applied DEP and/or EO forces may immobilize components of the sample on the surface of the electrode, may aggregate viral particles of the sample in one region of the microfluidic device, and may separate other components of the sample from the viral particles. The techniques may be performed rapidly, for example, in eight hours or less, and may not affect infectivity of the viral particles. In some embodiments, the sample may be labeled to enhance a response of one or more of the sample components to the DEP and/or EO forces.Type: ApplicationFiled: November 12, 2020Publication date: May 13, 2021Applicant: Fluid-Screen, Inc.Inventors: Slawomir Antoszczyk, Monika Weber, Robert Weber
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Publication number: 20200255863Abstract: A composition for expressing a polypeptide within a target organ, the composition comprising a delivery particle, and at least a first mRNA sequence complexed with, encapsulated by, or otherwise associated with the delivery particle. The mRNA sequence comprises a coding sequence which codes for the polypeptide, at least a first untranslated region (UTR) sequence, and at least one micro-RNA (miRNA) binding site sequence, wherein the miRNA binding site sequence is located within, immediately 5? to, or immediately 3? to, the first UTR sequence. The miRNA binding site sequence is selected so as to provide for differential expression of the coding sequence between first and second cell types comprised within the target organ. The composition may be used in combination with or to supplement other therapeutic approaches, including chemotherapy, oncolytic viral therapy, and cellular therapies.Type: ApplicationFiled: March 6, 2020Publication date: August 13, 2020Inventors: Romain Micol, Slawomir Antoszczyk