Patents by Inventor Slawomir Milewski

Slawomir Milewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted second generation derivatives of antifungal antibiotic amphotericin B and methods of their preparation and application
    Patent number: 9745335
    Abstract: The invention provides semisynthetic N-substituted derivatives of the antifungal antibiotic Amphotericin B and water soluble salts and complexes, pharmaceutical compositions and plant and building treatment products comprising the derivatives and their use as antifungal antibiotics.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: August 29, 2017
    Assignee: BLIRT S.A.
    Inventors: Edward Borowski, Natalia Salewska, Joanna Boros-Majewska, Maria Milewska, Malgorzata Wysocka, Slawomir Milewski, Izabela Chabowska, Michal Sabisz
  • Semisynthetic derivatives of Nystatin A
    Patent number: 9447136
    Abstract: The invention provides semisynthetic derivatives of Nystatin A1, water soluble salts and complexes, pharmaceutical compositions and plant protection products comprising the derivatives and their use, as antifungal antibiotics (Formula 1a).
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: September 20, 2016
    Assignee: BLIRT S.A.
    Inventors: Edward Borowski, Natalia Salewska, Joanna Boros-Majewska, Maria Milewska, Malgorzata Wysocka, Slawomir Milewski, Andrzej Skladanowski, Adam Treder, Ewa Sadowska, Izabela Chabowska
  • N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION
    Publication number: 20150291648
    Abstract: The invention provides semisynthetic N-substituted derivatives of the antifungal antibiotic Amphotericin B and water soluble salts and complexes, pharmaceutical compositions and plant and building treatment products comprising the derivatives and their use as antifungal antibiotics.
    Type: Application
    Filed: June 14, 2013
    Publication date: October 15, 2015
    Inventors: Edward Borowski, Natalia Salewska, Joanna Borosmajewska, Maria Milewska, Malgorzata Wysocka, Slawomir Milewski, Izabela Chabowska, Michal Sabisz
  • SEMISYNTHETIC DERIVATIVES OF NYSTATIN A1
    Publication number: 20150045316
    Abstract: The invention provides semisynthetic derivatives of Nystatin A1, water soluble salts and complexes, pharmaceutical compositions and plant protection products comprising the derivatives and their use, as antifungal antibiotics (Formula 1a).
    Type: Application
    Filed: March 7, 2013
    Publication date: February 12, 2015
    Applicant: BLIRT S.A.
    Inventors: Edward Borowski, Natalia Salewska, Joanna Borosmajewska, Maria Milewska, Malgorzata Wysocka, Slawomir Milewski, Andrzej Skladanowski, Adam Treder, Ewa Owska, Izabela Lacka
  • Tripeptides of N.sup.3 -4-methoxyfumaryl-L-2,3-diaminopropanoic acid
    Patent number: 4923965
    Abstract: The subject of this present invention is tripeptides of N.sup.3 -4-methoxyfumaryl-L-2,3-diaminopropanoic acid of the general formula ##STR1## where R is a hydrogen atom when R.sub.1 is the dipeptide residue containing the residue of alanine, methonine, valine, leucine or norvaline, or R and R.sub.1 have the same meaning and are the residue of monoaminomonocarboxylic aminoacid, such as those of alanine, methionine, valine, leucine, or norvaline, or R is the dipeptide residue containing the residue of alanine, methionine, valine, leucine, norvaline, lysine, ornithine, sarcosine, 2,4-diaminobutanoic acid and 2,3-diaminopropanoic acid, and R.sub.1 is a hydroxide group, and the method of their obtaining. The method of obtaining involves converting N.sup.2 -tetrbutoxycarbonyl, N.sup.3 -4-methoxyfumaroyl-L-2,3-diaminopropanoic acid into an active ester which is used for acylating a dipeptide or N.sup.2 -tetr-butoxycarbonyl, N.sup.
    Type: Grant
    Filed: July 21, 1988
    Date of Patent: May 8, 1990
    Assignee: Politechnika Gdanska
    Inventors: Ryszard Andruszkiewicz, Henryk Chmara, Slawomir Milewski, Edward Borowski, Maria Zaremba, Jerzy Borowski