Abstract: The present disclosure relates to a medicament delivery device sub-assembly having an injection needle assembly, a cartridge and a seal. The injection needle assembly has opposite distal and proximal ends, and has a retainer member configured to be connectable to a medicament container; a hub configured to be coaxially displaceable within the retainer member and provided with an injection needle having proximal and distal pointed ends; and a cap member interactively connected to both the hub and to the retainer member. A sealing member can be arranged between the cap member and the retainer member for preventing contamination of the injection needle before use. The seal seals a gap between the injection needle assembly and the cartridge. Methods of assembly are also described.

Abstract: A medicament delivery device (1) comprising: a tubular housing (3) extending along an axis (L), wherein the housing (3) has a proximal end (3a) provided with a proximal opening, and a distal end (3b), a delivery member cover (5) configured to be axially movable along the axis (L) relative to the housing (3) from an extend position, towards which the delivery member cover (5) is biased and in which the delivery member cover (5) protrudes from the proximal opening, to a retracted position, and a drive assembly arranged in the housing (3) and configured to be activated to initiate medicament delivery by movement of the delivery member cover (5) from the extended position towards the retracted position, wherein the housing (3) has an outer surface provided with a plurality of ribs (7) extending from the proximal end (3a) in a direction towards the distal end (3b).

Abstract: The present disclosure generally relates to medicament delivery devices such as autoinjectors, and particularly concerns pads for attaching medicament delivery devices such as autoinjectors to an injection site.

Abstract: The application describes syringe carriers for medicament delivery devices such as autoinjectors. One example concerns a syringe carrier for a syringe with a flange, the syringe carrier having a tubular housing extending along a longitudinal axis from a proximal end to a distal end and a syringe holder attached to the distal end of the tubular housing, wherein the syringe holder is configured to hold the flange of the syringe, and wherein the syringe holder comprises either a c-clip or a screw thread. Other associated syringe carriers, sub-assemblies, medicament delivery devices and corresponding methods are also described.

Abstract: A plunger rod for a medicament delivery device, the plunger rod comprising: a tubular body extending along a longitudinal axis between a closed end and an open end; and a whistle orifice on a tubular wall of the tubular body; the whistle orifice is positioned between the open end of the tubular body and the closed end of the tubular body.

Abstract: The application describes syringe carriers for medicament delivery devices such as autoinjectors. One example concerns a syringe carrier for a syringe with a flange, the syringe carrier having a tubular housing extending along a longitudinal axis from a proximal end to a distal end and a syringe holder attached to the distal end of the tubular housing, wherein the syringe holder is configured to hold the flange of the syringe, and wherein the syringe holder comprises either a c-clip or a screw thread. Other associated syringe carriers, sub-assemblies, medicament delivery devices and corresponding methods are also described.

Abstract: A needle shield remover for assembly with a cap of a medicament delivery device is presented where the needle shield remover has a main body, at least a flexible first grabber, and at least a flexible second grabber. The first grabber and second grabber extend from the main body and are inclined in relation to the longitudinal axis of the needle shield remover such that they cross each other to form a receiving space configured to receive a delivery member shield.

Abstract: A pneumatic power pack for a medicament delivery device is presented having a pressurized gas container storing pressurized gas and an activation assembly for releasing the pressurized gas from the gas source. The activation assembly including a rupturer having a sharp end, an activator, and a rotator coupled with the activator and the gas container. The activator is configured to move from a first position toward a second position to causes a rotation of the rotator which then drives the gas source towards the sharp end of the rupturer to release the pressurized gas.

Abstract: This application describes syringe carriers for medicament delivery devices such as autoinjectors. In particular, an example syringe carrier is tubular and extends along a longitudinal axis from a proximal end to a distal end, the syringe carrier comprising a base section at the distal end of the syringe carrier, the base section having a fixed circumference, at least one arm extending towards the proximal end of the syringe carrier from the base section, and an expandable ring attached to the proximal end of the at least one arm, wherein the ring extends entirely around the longitudinal axis of the syringe carrier in the circumferential direction. Various other syringe carriers and associated medicament delivery devices and methods are described.

Abstract: A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

Abstract: A medicament delivery device package assembly is provided having a body defining an interior reservoir for containing a medicament delivery device; a motion sensor attached to the body; wherein the medicament delivery device package assembly is configured to be placed in a storage unit with a door; wherein the door is movable between a closed position where an inner space of the storage unit is covered by the door and an open position where the inner space of the storage unit is not covered by the door; and wherein the motion sensor is configured to detect an opening movement of the door from the closed position to the open position.

Abstract: A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

Abstract: A drive mechanism for a delivery device is presented containing, a rotator having an outer surface and an inner surface, the rotator configured to rotate from a first position to a second position. A needle cover having an inner surface that engages the outer surface of the rotator. A rotatable plunger rod having an outer surface configured to engage the inner surface of the rotator. When the rotator rotates from the first position to the second position, the rotatable plunger rod is rotated by the rotator and a plunger rod spring is released from a pre-tensioned state to exert a force on the rotatable plunger rod.

Abstract: A hub device configured to enable wireless communication between portable medical devices and an external device, where the hub device has a radio transceiver device configured to receive portable medical device data from each portable medical device and configured to transmit received portable medical device data to the external device, an energy storage unit configured to power the radio transceiver device, and an energy harvesting circuit configured to harvest radio frequency energy to charge the energy storage unit, wherein the hub device is configured to communicate with the portable medical devices using a protocol that for each portable medical device enables a unique portable medical device identifier to be included in the portable medical device data, and wherein the hub device has processing circuitry configured to establish a communications link with a portable medical device if the processing circuitry confirms recognition of the unique portable medical device identifier received from the portable

Abstract: The present disclosure provides a medicament delivery device including a housing, a skin sensor positioned at least partially within the housing, and a transmitter positioned within the housing. The medicament delivery device is configured to determine, via the skin sensor, whether or not the medicament delivery device is attached to the skin of the user. In response to a determination that the medicament delivery device is attached to the skin of the user, the medicament delivery device prevents transmission of unique identification data associated with the medicament delivery device and/or the user from the transmitter. In response to a determination that the medicament delivery device is not attached to the skin of the user, the medicament delivery device transmits, via the transmitter, the unique identification data to one or more external receivers.

Abstract: Pads for attaching medicament delivery devices such as autoinjectors to an injection site are presented that include a pad extending along an axis from a proximal end to a distal end, where the proximal end is the end of the pad adjacent to an injection site when the pad is in use, the pad can have an attachment portion configured to receive a medicament delivery device and a second attachment portion attached to the attachment portion, wherein the second attachment portion is arranged at the proximal end of the pad, and wherein the second attachment portion is configured to attach the pad to said injection site when the pad is in use.

Abstract: A drive mechanism for a delivery device is presented containing, a rotator having an outer surface and an inner surface, the rotator configured to rotate from a first position to a second position. A needle cover having an inner surface that engages the outer surface of the rotator. A rotatable plunger rod having an outer surface configured to engage the inner surface of the rotator. When the rotator rotates from the first position to the second position, the rotatable plunger rod is rotated by the rotator and a plunger rod spring is released from a pre-tensioned state to exert a force on the rotatable plunger rod.

Abstract: A needle insertor for a medicament delivery device is presented having a driver having a first part movably arranged within the case and a second part connected to the base, a needle assembly movably held by the first part in the case, a rotator arranged in the case and configured to engage the first part for moving the driver, an energy accumulation member configured to interact with the rotator for applying a rotational force on the rotator, a movable stop arranged on the base and configured to interact with the rotator for preventing the rotator from rotating. The first part has a first position where the needle assembly is held inside the case, a second position where the needle portion is positioned outside the case after being moved to pass through the injection site end, and a third position where the needle portion is positioned inside the case.

Abstract: A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

Abstract: A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.