Patents by Inventor Slobodan Vukicevic

Slobodan Vukicevic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blood biomarkers for bone fracture and cartilage injury
    Patent number: 8182998
    Abstract: Blood biomarkers are described for use in methods and compositions to determine whether an individual has sustained a bone fracture or a cartilage injury.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: May 22, 2012
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Lovorka Grgurevic, Boris Macek, Slobodan Vukicevic
  • Methods and compositions for regenerating articular cartilage
    Patent number: 8119591
    Abstract: Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: February 21, 2012
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Mislav Jelic
  • NOVEL THERAPIES FOR CHRONIC RENAL FAILURE
    Publication number: 20120004171
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain proteins of, or based upon, the osteogenic protein/bone morphogenetic protein (OP/BMP) family within the TGF-? superfamily of proteins.
    Type: Application
    Filed: August 11, 2011
    Publication date: January 5, 2012
    Applicant: STRYKER CORPORATION
    Inventors: Kuber T. Sampath, Charles M. Cohen, Slobodan Vukicevic
  • THERAPIES FOR ACUTE RENAL FAILURE
    Publication number: 20110257093
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of, acute renal failure, or subject to, or at risk of, inflammation, neutrophil-mediated cell damage, and apoptosis resulting from tissue damage or injury. The methods involve the administration of certain proteins of the osteogenic protein/bone morphogenetic protein (OP/BMP) family within the TGF-? superfamily of proteins.
    Type: Application
    Filed: April 4, 2011
    Publication date: October 20, 2011
    Applicant: STRYKER CORPORATION
    Inventors: Charles M. Cohen, Kuber T. Sampath, Slobodan Vukicevic
  • Therapies for chronic renal failure
    Patent number: 8017580
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain proteins of, or based upon, the osteogenic protein/bone morphogenetic protein (OP/BMP) family within the TGF-? superfamily of proteins.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: September 13, 2011
    Assignee: Stryker Corporation
    Inventors: Charles M Cohen, Kuber T. Sampath, Slobodan Vukicevic
  • BMP-1 PROCOLLAGEN C-PROTEINASE FOR DIAGNOSIS AND TREATMENT OF BONE AND SOFT TISSUE DEFECTS AND DISORDERS
    Publication number: 20110076281
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Application
    Filed: December 9, 2010
    Publication date: March 31, 2011
    Applicant: GENERA ISTRAZIVANJA d.o.o
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Boris Macek
  • Control of Exocrine Pancreatic Function Using Bone Morphogenetic Proteins
    Publication number: 20110047633
    Abstract: Methods are described for controlling exocrine pancreatic function, for reducing the level of amylase in the blood, and for treating pancreatitis in an individual comprising administering to the individual a bone morphogenetic protein (BMP). Methods for identifying candidate molecules for use in treating diabetes are also described.
    Type: Application
    Filed: September 8, 2010
    Publication date: February 24, 2011
    Applicant: GENERA ISTRAZIVANJA D.O.O.
    Inventors: Slobodan VUKICEVIC, Petra SIMIC
  • BMP-1 procollagen c-proteinase for diagnosis and treatment of bone and soft tissue defects and disorders
    Patent number: 7850964
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: December 14, 2010
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Boris Macek
  • ADAMTS4 as a blood biomarker and therapeutic target for chronic renal failure
    Publication number: 20100254997
    Abstract: ADAMTS4 is found to be useful as a blood biomarker for chronic renal failure and also as a therapeutic target for treating chronic renal failure in a human individual. A change in the level of expression of selected genes as disclosed herein in kidney tissue of an individual may also be used to diagnose chronic renal failure in an individual.
    Type: Application
    Filed: June 20, 2008
    Publication date: October 7, 2010
    Applicant: GENERA ISTRAZIVANJA D.O.O.
    Inventors: Lovorka Grgurevic, Slobodan Vukicevic
  • Devices and method for repair of larynx, trachea, and other fibrocartilaginous tissues
    Patent number: 7803369
    Abstract: Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci, intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
    Type: Grant
    Filed: July 28, 2005
    Date of Patent: September 28, 2010
    Assignee: Stryker Corporation
    Inventors: Slobodan Vukicevic, Vladimir Katic, Kuber T. Sampath
  • BLOOD BIOMARKERS FOR BONE FRACTURE AND CARTILAGE INJURY
    Publication number: 20100112721
    Abstract: Blood biomarkers are described for use in methods and compositions to determine whether an individual has sustained a bone fracture or a cartilage injury.
    Type: Application
    Filed: April 28, 2008
    Publication date: May 6, 2010
    Inventors: Lovorka Grgurevic, Boris Macek, Slobodan Vukicevic
  • Therapies for acute renal failure
    Publication number: 20100105621
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of, acute renal failure, or subject to, or at risk of, inflammation, neutrophil-mediated cell damage, and apoptosis resulting from tissue damage or injury. The methods involve the administration of certain proteins of the osteogenic protein/bone morphogenetic protein (OP/BMP) family within the TGF-? superfamily of proteins.
    Type: Application
    Filed: August 11, 2009
    Publication date: April 29, 2010
    Inventors: Charles M. Cohen, Kuber T. Sampath, Slobodan Vukicevic
  • Devices and methods for repair of larynx, trachea and other fibrocartilaginous tissues
    Publication number: 20100074883
    Abstract: Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci, intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
    Type: Application
    Filed: July 28, 2005
    Publication date: March 25, 2010
    Inventors: Slobodan Vukicevic, Vladimir Katic, Kuber Sampath
  • Repair of larynx, trachea, and other fibrocartilaginous tissues
    Publication number: 20100074936
    Abstract: Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci, intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
    Type: Application
    Filed: August 20, 2007
    Publication date: March 25, 2010
    Inventors: Slobodan Vukicevic, Vladimir Katic, Kuber T. Sampath
  • Repair of larynx, trachea, and other fibrocartilaginous tissues
    Publication number: 20100075896
    Abstract: Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
    Type: Application
    Filed: August 20, 2007
    Publication date: March 25, 2010
    Inventors: Slobodan Vukicevic, Vladimir Katic, Kuber T. Sampath
  • WHOLE BLOOD-DERIVED COAGULUM DEVICE FOR TREATING BONE DEFECTS
    Publication number: 20090317438
    Abstract: Whole blood-derived coagulum devices are described for use in treating bone defects.
    Type: Application
    Filed: July 23, 2007
    Publication date: December 24, 2009
    Applicant: GENERA DOO
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Hermann Oppermann
  • Method for repairing a defect in an intervertebral disc
    Patent number: 7572440
    Abstract: Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci, intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: August 11, 2009
    Assignee: Stryker Corporation
    Inventors: Slobodan Vukicevic, Vladimir Katic, Kuber T. Sampath
  • BMP-1 PROCOLLAGEN C-PROTEINASE FOR DIAGNOSIS AND TREATMENT OF BONE AND SOFT TISSUE DEFECTS AND DISORDERS
    Publication number: 20090191255
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Application
    Filed: July 23, 2007
    Publication date: July 30, 2009
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Boris Macek
  • Methods and Compositions for Regenerating Articular Cartilage
    Publication number: 20090143286
    Abstract: Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.
    Type: Application
    Filed: August 1, 2006
    Publication date: June 4, 2009
    Applicant: GENERA DOO
    Inventors: Slobodan Vukicevic, Mislav Jelic
  • Method for repairing a defect in an intervertebral disc
    Patent number: RE42954
    Abstract: Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, trachea, interarticular menisci, intervertebral discs, ear, nose, ribs and other fibrocartilaginous tissues in a mammal.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: November 22, 2011
    Assignee: Stryker Corporation
    Inventors: Slobodan Vukicevic, Vladimir Katic, Kuber T. Sampath