Abstract: System, method, and computer program product for performing an operation, the operation comprising operating a tablet in a work mode when the tablet is oriented according to a first orientation, operating the tablet in an alternate mode when the tablet is oriented according to a second orientation, and outputting a content for display on the tablet based on a current operating mode of the tablet.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

Abstract: This application relates to a low profile, small footprint cooling stack that does not extend substantially beyond a footprint of an integrated circuit to which it is affixed. The cooling stack utilizes a number of beam springs that supply a seating force to the integrated circuit by way of a metal slug. In some embodiments, a bottom surface of the metal slug can be contoured in accordance with a top surface of the integrated circuit and/or socket. In other embodiments a gap between peripheral portion of a bottom surface of the metal slug and an associated printed circuit board can be filled by a layer of foam to reduce auditory signals generated by the integrated circuit.

Abstract: A new variety of sweetpotato identified as ‘LA06-52’ is disclosed having disease resistance to Fusarium wilt, Rhizopus soft rot (intermediate), southern root-knot nematode, and Streptomyces soil rot, an orange flesh, copper skin and high yield characteristics.

Abstract: Despite its narrow therapeutic window, lithium is regarded as the gold standard comparator and benchmark treatment for mania. Attempts to find new drugs with similar therapeutic activities have yielded new chemical entities. However, these new drugs have yet to match the many bioactivities attributable to lithium's efficacy for the treatment of neuropsychiatric diseases. Consequently, an intense effort for re-engineering lithium therapeutics using crystal engineering is underway. The evaluation of pharmacokinetics of previously unexplored lithium salts with organic anions (i.e. lithium salicylate) has found that these lithium salts exhibit profoundly different pharmacokinetics compared to the more common FDA approved salt, lithium carbonate, in rats. Remarkably, lithium salicylate produced elevated blood and brain levels of lithium beyond 48 hours post-dose without the sharp peak that contributes to the toxicity problems of current lithium therapeutics.

Abstract: Automatic generation of a mosaic comprising a plurality of geospatial images. An embodiment of the automatic mosaic generation may include automated source image selection that includes comparison of source images to base layer image to determine radiometric similar source images. Additionally, an embodiment of an automatic cutline generator may be provided to automatically determine a cutline when merging two images such that radiometric differences between the images along the cutline are reduced. In this regard, less perceivable cutlines may be provided. Further still, an embodiment of a radiometric normalization module may be provided that may determine radiometric adjustments to source images to match certain properties of the base layer image. In some embodiments, when processing source images, the source images may be downsampled during a portion of the processing to reduce computational overhead. Additionally, some highly parallel computations may be performed by a GPU to further enhance performance.

Abstract: A photoresist modelling system includes a mathematical model for a photolithography process. The mathematical model may be executable using a computer processor. The mathematical model may be used to model a photoresist as formed on a semiconductor wafer surface. A blocked polymer concentration gradient equation may be implemented into the mathematical model. The blocked polymer concentration gradient equation may describe an initial concentration gradient of a blocked polymer in the photoresist being modelled by the mathematical model.

Abstract: A method for providing intelligent ticket suggestions using a transaction device for transit fare purchases includes receiving an input from a fare media. The input includes an identifier associated with a user of the fare media. The input is communicated to a data store to identify a usage history and a purchase history for the user of the fare media. The usage history and purchase history are associated with the user of the fare media based on the identifier. The usage history and the purchase history for the user are received from the data store and a geographically closest transit stop relative to the transaction device is determined. Transit timetables and transit products available for purchase based on the geographically closest transit stop are identified. Transit product suggestions are generated based on one or more of the usage history, purchase history, transit timetables, or transit fares available for purchase.

Abstract: Methods of fabricating solar cells with tunnel dielectric layers are described. Solar cells with tunnel dielectric layers are also described.

Abstract: A method and apparatus for mapping distributed generators (DGs) to corresponding power grid feeder lines. In one embodiment, the method comprises obtaining grid data pertaining to a power grid that comprises a plurality of feeder lines; obtaining, for each distributed generator (DG) of a plurality of DGs coupled to the plurality of feeder lines, DG data pertaining to the DG; and determining, based on the grid data and the DG data, a mapping that identifies to which feeder line of the plurality of feeder lines each of the DGs of the plurality of DGs is coupled.

Abstract: An external fixator for mounting to a patient's leg or other anatomy to stabilize bones in the patient's leg or other anatomy includes a first ring including a first plurality a slots therein and a second ring including a second plurality of slots therein. A foot-plate has a generally U-shape and a third plurality of slots therein. A first strut is mounted between the first ring and the second ring. The first strut includes an upper tube, a lower tube, a first telescoping element securing the upper tube to the lower tube and first and second end fittings secured to ends of the upper and lower tubes, respectively. The first end fitting secures the first strut to the first ring and the second end fitting secures the first strut to the second ring.

Abstract: A continuous ink jet printer including an ink tank for holding ink, an ink nozzle in fluid communication with the ink tank for ejecting ink droplets, and a gutter for receiving, through an ink-receiving inlet thereof, ink droplets which are not used for printing. A gutter flow path starts at the ink-receiving inlet for ink that has entered the gutter through the ink-receiving inlet, and provides fluid communication to the ink tank. A return line is in fluid communication with the print head for conveying air to enter the gutter flow path. A makeup tank is in vapor communication with the ink tank to allow air to be conveyed from the ink tank to the makeup tank. A condenser is in fluid communication with the makeup tank and the return line for condensing solvent.

Abstract: A method and system for achieving a link budget improvement in a diverse OFDM radio system by addressing the timing misalignment issue that can occur due to the differences in propagation time in signals between mobile stations and Radio Access Nodes. Timing misalignment is shared or split between the primary path to a primary Radio Access Node and a diverse path to a diverse Radio Access Node. The relative timing offsets between mobile stations are adjusted, the mobile stations are grouped into zones using a variety of different grouping techniques, and the transmission for each mobile station is scheduled, using one or more of a variety of scheduling techniques.

Abstract: A tap dispenser having a main body, said main body having a main body interior portion and an opposing main body exterior portion; a liquid flow pathway passing through the main body; a vent pathway passing through the main body, wherein air transport through the vent pathway is separated from liquid transport through said liquid flow pathway and wherein the vent pathway has a vent pathway inlet and an opposing vent pathway outlet; a vent valve operably engaged with the vent pathway outlet; and a liquid flow valve operably engaged with the liquid flow pathway.

Abstract: The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for IL-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-IL-6 antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-IL-6 antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-IL-6 antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with IL-6.

Abstract: Systems directed to the art of setting a hook in a fish mouth have an activation member assembly removably interfaced with a spring-loaded plunger assembly. A fish hook is attached via fishing lines to both the activation member assembly and the plunger assembly. Pulling the hook releases the plunger assembly from the activation member assembly and pulls the line attached to the plunger assembly, setting the hook in the fish's mouth.

Abstract: A system for clipping tissue includes a clip having first and second jaws. Each of the first and second jaws defines an opening through which a control wire passes. A collapsible member is coupled between the first and second jaws. The member is biased to urge the first and second jaws away from one another along an axis of the control wire to a first expanded configuration. The first and second jaws are movable against the bias of the member via the control wire to a second contracted configuration in which the first and second jaws are moved along the axis of the control wire toward one another to lockingly engage tissue received therebetween. The movement of control wire causes a corresponding movement of the first jaw relative to the second jaw to move the first and second jaws from the first expanded configuration to the second contracted configuration.

Abstract: A cooling and reactant removal system includes first and second gate valves. An outlet of the first gate valve is arranged in fluid communication with the process volume of the processing chamber. A filter is arranged in fluid communication with an inlet of the first gate valve. An inlet of the second gate valve is arranged in fluid communication with the process volume of the processing chamber. A gas amplifier has a first inlet, a second inlet, an outlet and at least one Coanda surface. Compressed gas received at the first inlet of the gas amplifier is directed across the Coanda surface. The second inlet of the gas amplifier is in fluid communication with the outlet of the second gate valve. The outlet of the gas amplifier is in fluid communication with a scrubbed exhaust system.

Abstract: In certain systems disclosed herein, one or more of a first vascular access port and a second vascular access port can be selected by a customer. Each of the first and second vascular access ports can be implanted subcutaneously within a patient, and each can include a base configured to be attached to a vessel, a body that extends away from the base, and a guidance passageway that extends through the body and the base and includes a funnel region. A maximum height defined by the base and body of the second vascular access port can be greater than a maximum height defined by the base and body of the first vascular access port.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.