Patents by Inventor So Yeon Koo

So Yeon Koo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IMPROVING IN VIVO SURVIVAL OF MIDBRAIN DOPAMINE NEURONS
    Publication number: 20250017979
    Abstract: The present disclosure provides methods for improving in vivo survival of midbrain dopamine (mDA) neurons (e.g., in vitro differentiated mDA neurons) by suppressing p53-mediated apoptosis of mDA neurons. The present disclosure further provides methods for treating a subject (e.g., a subject suffering from neurodegeneration of midbrain dopamine neurons, and/or a neurodegenerative disease), comprising administering to the subject one or more mDAs, wherein p53-mediated apoptosis of the one or more mDA neurons is suppressed.
    Type: Application
    Filed: September 18, 2024
    Publication date: January 16, 2025
    Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER, SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH, MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES
    Inventors: Lorenz Studer, Taewan Kim, So Yeon Koo
  • METHODS OF GENERATING MIDBRAIN DOPAMINE NEURONS, MIDBRAIN NEURONS AND USES THEREOF
    Publication number: 20230143486
    Abstract: The present disclosure provides methods for generating midbrain dopamine neurons and precursors thereof, midbrain dopamine neurons and precursors thereof generated by such methods and compositions comprising such cells, and uses thereof for preventing, modeling, and/or treating a neurological disorder.
    Type: Application
    Filed: September 30, 2022
    Publication date: May 11, 2023
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz STUDER, Tae-Wan KIM, So-Yeon KOO
  • METHODS OF GENERATING AND ISOLATING MIDBRAIN DOPAMINE NEURONS
    Publication number: 20220177835
    Abstract: The present disclosure provides methods for generating midbrain dopamine neurons (mDAs) and precursors thereof, mDAs and precursors thereof generated by such methods and compositions comprising such cells, and uses thereof for preventing and/or treating neurological disorders. The present disclosure further provides methods of isolating mDAs and precursors thereof from a cell population using novel surface markers.
    Type: Application
    Filed: February 25, 2022
    Publication date: June 9, 2022
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz Studer, Taewan Kim, Stefan Irion, So Yeon Koo