Patents by Inventor Sode Koji

Sode Koji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholesterol oxidase mutants, compositions, devices, kits and uses thereof
    Patent number: 9284534
    Abstract: Compositions, devices, kits and methods are disclosed for assaying cholesterol with a cholesterol oxidase mutant that has been modified at an amino acid residue involved in the active site. The cholesterol oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: March 15, 2016
    Assignees: Ultizymer International, Ltd., Roche Diabetes Care, Inc.
    Inventors: Katsuhiro Kojima, Kazushige Mori, Sode Koji
  • Glucose oxidase mutants, compositions, devices, kits and uses thereof
    Patent number: 8999140
    Abstract: Compositions, devices, kits and methods are disclosed for assaying glucose with a glucose oxidase mutant that has been modified at an amino acid residue involved in the active site. The glucose oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: April 7, 2015
    Assignees: Roche Diagnostics Operations, Inc., Ultizyme International, Ltd.
    Inventors: Katsuhiro Kojima, Kazushige Mori, Sode Koji
  • Fructosyl peptidyl oxidase
    Patent number: 8962271
    Abstract: In one form, a fructosyl peptidyl oxidase derived from a budding yeast Phaeosphaeria nodorum for assaying a glycated protein in a sample is provided. The fructosyl peptidyl oxidase has higher activity toward fructosyl valine as well as fructosyl valyl histidine, and may be useful in assaying HbA1c with higher sensitivity and specificity. Still, other forms include unique methods, techniques, systems and devices involving a fructosyl peptidyl oxidase.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: February 24, 2015
    Assignees: Roche Diagnostics Operations, Inc., Ultizyme International, Ltd.
    Inventors: Kazunori Ikebukuro, Sode Koji
  • CHOLESTEROL OXIDASE MUTANTS, COMPOSITIONS, DEVICES, KITS AND USES THEREOF
    Publication number: 20140255959
    Abstract: Compositions, devices, kits and methods are disclosed for assaying cholesterol with a cholesterol oxidase mutant that has been modified at an amino acid residue involved in the active site. The cholesterol oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity.
    Type: Application
    Filed: February 24, 2014
    Publication date: September 11, 2014
    Applicants: Ultizyme International, Ltd., Roche Diagnostics Operations, Inc.
    Inventors: Katsuhiro Kojima, Kazushige Mori, Sode Koji
  • GLUCOSE OXIDASE MUTANTS, COMPOSITIONS, DEVICES, KITS AND USES THEREOF
    Publication number: 20140248645
    Abstract: Compositions, devices, kits and methods are disclosed for assaying glucose with a glucose oxidase mutant that has been modified at an amino acid residue involved in the active site. The glucose oxidase mutant has reduced oxidase activity while substantially maintaining its dehydrogenase activity.
    Type: Application
    Filed: February 24, 2014
    Publication date: September 4, 2014
    Applicants: Ultizyme International, Ltd., Roche Diagnostics Operations, Inc.
    Inventors: Katsuhiro Kojima, Kazushige Mori, Sode Koji
  • NOVEL FRUCTOSYL PEPTIDYL OXIDASE
    Publication number: 20140227728
    Abstract: In one form, a fructosyl peptidyl oxidase derived from a budding yeast Phaeosphaeria nodorum for assaying a glycated protein in a sample is provided. The fructosyl peptidyl oxidase has higher activity toward fructosyl valine as well as fructosyl valyl histidine, and may be useful in assaying HbA1c with higher sensitivity and specificity. Still, other forms include unique methods, techniques, systems and devices involving a fructosyl peptidyl oxidase.
    Type: Application
    Filed: March 27, 2014
    Publication date: August 14, 2014
    Applicants: Roche Diagnostics Operations, Inc., Ultizyme International, LTD
    Inventors: Kazunori Ikebukuro, Sode Koji
  • Fructosyl amino acid oxidase
    Patent number: 8497083
    Abstract: In one form, a mutant fructosyl amino acid oxidase modified at an amino acid residue involved in a proton relay system is provided. The mutant fructosyl amino acid oxidase has reduced oxidase activity while substantially maintaining its dehydrogenase activity. Other forms include an assay device and assay method for measuring glycated protein. Still, other forms include unique methods, techniques, systems and devices involving a mutant fructosyl amino acid oxidase.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: July 30, 2013
    Assignees: Roche Diagnostics Operations, Inc.
    Inventors: Kazunori Ikebukuro, Sode Koji
  • FRUCTOSYL AMINO ACID OXIDASE
    Publication number: 20120208226
    Abstract: In one form, a mutant fructosyl amino acid oxidase modified at an amino acid residue involved in a proton relay system is provided. The mutant fructosyl amino acid oxidase has reduced oxidase activity while substantially maintaining its dehydrogenase activity. Other forms include an assay device and assay method for measuring glycated protein. Still, other forms include unique methods, techniques, systems and devices involving a mutant fructosyl amino acid oxidase.
    Type: Application
    Filed: February 3, 2012
    Publication date: August 16, 2012
    Inventors: Kazunori Ikebukuro, Sode Koji
  • NOVEL FRUCTOSYL PEPTIDYL OXIDASE
    Publication number: 20120202235
    Abstract: In one form, a fructosyl peptidyl oxidase derived from a budding yeast Phaeosphaeria nodorum for assaying a glycated protein in a sample is provided. The fructosyl peptidyl oxidase has higher activity toward fructosyl valine as well as fructosyl valyl histidine, and may be useful in assaying HbA1c with higher sensitivity and specificity. Still, other forms include unique methods, techniques, systems and devices involving a fructosyl peptidyl oxidase.
    Type: Application
    Filed: February 3, 2012
    Publication date: August 9, 2012
    Inventors: Kazunori Ikebukuro, Sode Koji