Patents by Inventor Sofia D. Merajver

Sofia D. Merajver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies
    Patent number: 7888389
    Abstract: Disclosed are copper-binding compounds with improved properties and methods of using such compounds in the prevention and treatment of angiogenic diseases, such as cancer. Advantages of the invention include the enhanced stability of the compounds, which is achieved without reduction in efficacy. Pharmaceutical compositions, therapeutic kits and combination treatment methods and uses are also provided.
    Type: Grant
    Filed: July 23, 2003
    Date of Patent: February 15, 2011
    Assignee: The Regents of the University of Michigan
    Inventors: George J. Brewer, Sofia D. Merajver, Dimitri Coucouvanis
  • Methods and compositions for the treatment of angiogenic diseases
    Patent number: 7438931
    Abstract: Provided are agents that can bind to copper, and form a tripartite complex with protein, and the use of these agents in the prevention and treatment of diseases with a vascular component, such as solid tumors. Compositions and methods for combination therapy of these diseases, including cancer, as well as therapeutic kits, are also provided.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: October 21, 2008
    Assignee: The Regents of The University of Michigan
    Inventors: George J. Brewer, Sofia D. Merajver, Dimitri Coucouvanis
  • Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies
    Publication number: 20040259945
    Abstract: Disclosed are copper-binding compounds with improved properties and methods of using such compounds in the prevention and treatment of angiogenic diseases, such as cancer. Advantages of the invention include the enhanced stability of the compounds, which is achieved without reduction in efficacy. Pharmaceutical compositions, therapeutic kits and combination treatment methods and uses are also provided.
    Type: Application
    Filed: July 23, 2003
    Publication date: December 23, 2004
    Applicant: The Regents of The University of Michigan
    Inventors: George J. Brewer, Sofia D. Merajver, Dimitri Coucouvanis
  • Methods and compositions for the prevention or treatment of cancer
    Patent number: 6703050
    Abstract: Provided are agents that can bind to copper, and form a tripartite complex with protein, and the use of these agents in the prevention and treatment of diseases with a vascular component, such as solid tumors. Compositions and methods for combination therapy of these diseases, including cancer, as well as therapeutic kits, are also provided.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: March 9, 2004
    Assignee: The Regents of the University of Michigan
    Inventors: George J. Brewer, Sofia D. Merajver, Dimitri Coucouvanis