Patents by Inventor Sofia FERRER CABRERA

Sofia FERRER CABRERA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLQ inhibitors
    Patent number: 12653828
    Abstract: The specification generally relates to compounds of Formula (I): or a stereoisomer or pharmaceutically salt thereof, wherein G, Ga, Gb, X, Y, R1, R2, Q1, Q2, and Q3 have any of the meanings defined herein, together with compositions containing them and their use in therapy. The compounds are inhibitors of the polymerase, DNA polymerase theta (Pol? or POLQ), and are thereby particularly useful in the treatment of cancer.
    Type: Grant
    Filed: December 5, 2023
    Date of Patent: June 16, 2026
    Assignee: ASTRAZENECA AB
    Inventors: Bernard Barlaam, Michael Bodnarchuk, Gail Wrigley, Jon Winter-Holt, Oliver Turner, Ariamala Gopalsamy, Jason Shields, Sofia Ferrer Cabrera, Helen Elizabeth Jones
  • POLQ INHIBITORS
    Publication number: 20240366615
    Abstract: The specification generally relates to compounds of Formula (I): or a stereoisomer or pharmaceutically salt thereof, wherein G, Ga, Gb, X, Y, R1, R2, Q1, Q2, and Q3 have any of the meanings defined herein, together with compositions containing them and their use in therapy. The compounds are inhibitors of the polymerase, DNA polymerase theta (Pol? or POLQ), and are thereby particularly useful in the treatment of cancer.
    Type: Application
    Filed: December 5, 2023
    Publication date: November 7, 2024
    Inventors: BERNARD BARLAAM, MICHAEL BODNARCHUK, GAIL WRIGLEY, JON WINTER-HOLT, OLIVER TURNER, ARIAMALA GOPALSAMY, JASON SHIELDS, SOFIA FERRER CABRERA
  • BRANCHED MACROCYCLIC 4-(PYRAZOL-5-YL)-INDOLE DERIVATIVES AS INHIBITORS OF MCL-1
    Publication number: 20240124487
    Abstract: The present invention relates to pharmaceutical agents of formula (I) useful for therapy and/or prophylaxis in a subject, pharmaceutical composition comprising such compounds, and their use as MCL-1 inhibitors, useful for treating diseases such as cancer.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 18, 2024
    Inventors: Frederik Jan Rita ROMBOUTS, Adriana-Ingrid VELTER, Petrus Jacobus Johannes Antonius BUIJNSTERS, Sofia FERRER CABRERA
  • MACROCYCLIC ETHER CONTAINING INDOLE DERIVATIVES AS INHIBITORS OF MCL-1
    Publication number: 20230250109
    Abstract: The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a subject, pharmaceutical composition comprising such compounds, and their use as MCL-1 inhibitors, useful for treating diseases such as cancer.
    Type: Application
    Filed: July 8, 2021
    Publication date: August 10, 2023
    Inventors: Benoît Christian Albert Ghislain DE BOECK, Petrus Jacobus Johannes Antonius BUIJNSTERS, Sofia FERRER CABRERA, Aldo PESCHIULLI, Tristan REUILLON, Frederik Jan Rita ROMBOUTS, Adriana-Ingrid VELTER