Patents by Inventor Sofia FROST

Sofia FROST has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240082437
    Abstract: The present invention relates to antibodies which bind to antigens on target cells and which target effector moieties to said cells, and to methods of using the same.
    Type: Application
    Filed: January 10, 2022
    Publication date: March 14, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian KLEIN, Alexander HAAS, Sabine IMHOF-JUNG, Sofia FROST
  • Publication number: 20230272116
    Abstract: The present invention relates to a set of antibodies which bind to antigens on target cells and which target radionuclides to said cells, and to methods of using the same. The antibodies each comprising a Fab binding to the target antigen fused at the C-terminus of the VH to the N-terminus of the Fc and a VH or VL binding to a radiolabelled compound. The VH or VL are fused at the C-terminus to the N-terminus of the Fc. VH and VL form an antigen binding site when the antibody binds via the scFv to the target antigen.
    Type: Application
    Filed: July 8, 2021
    Publication date: August 31, 2023
    Inventors: Alexander HAAS, Sabine IMHOF-JUNG, Christian KLEIN, Sofia FROST
  • Publication number: 20220267463
    Abstract: The present invention relates to antibodies which bind to antigens on target cells and which target radionuclides to said cells, and to methods of using the same.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 25, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Pablo UMANA, Sabine IMHOF-JUNG, Alexander HAAS, Christian KLEIN, Sofia FROST, Felix BORMANN, Guy GEORGES, Sebastian FENN, Florian LIPSMEIER, Daniela MATSCHEKO, Joerg MOELLEKEN, Barbara WEISER
  • Publication number: 20220031871
    Abstract: The present application relates to antibodies which bind specifically to chelated radionuclides, including bispecific antibodies, It further relates to the use of such bispecific antibodies in applications such as radioimmunoimaging and radioimmunotherapy. It additionally relates to clearing agents and useful in such methods.
    Type: Application
    Filed: April 16, 2019
    Publication date: February 3, 2022
    Applicants: Hoffmann-La Roche Inc., Orano Med SAS
    Inventors: Julien TORGUE, Paul JUREK, Federico ROJAS-QUIJANO, Garry E. KIEFER, Olivier FREYTAG, Christian GERDES, Christian KLEIN, Pablo UMANA, Alexander HAAS, Sofia FROST, Amal SAIDI, Tapan NAYAK