Patents by Inventor Sofia Judite Marques Da Costa

Sofia Judite Marques Da Costa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9610335
    Abstract: The invention relates to fusion proteins comprising an amino acid sequence of a fragment H corresponding to a fragment of a calcium binding protein excreted-secreted by adult worms of Fasciola hepatica, followed by an amino acid sequence corresponding to a unrelated protein or fragment of protein, pharmaceutical compositions, vaccines and adjuvants containing the immunogen, to a process for their preparation, another process for the production of antibodies and their use. The present invention relates to the preparation of immunogens by the addition of a peptide sequence. Thus the present invention is useful for producing an immune response, with increases in specific antibody titers in serum against proteins or other antigens and can be applied in particular for the production of specific polyclonal antibodies, immunotherapy and immunoprophylaxis.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: April 4, 2017
    Assignees: ESCOLA SUPERIOR AGRÁRIA DE COIMBRA, HITAG—BIOTECHNOLOGY, LDA.
    Inventors: Maria Antónia Pereira Da Conceição, Sofia Judite Marques Da Costa, António Manuel Oliveira Castro, André Augusto Da Silva Almeida
  • Publication number: 20120328621
    Abstract: The invention relates to fusion proteins comprising an amino acid sequence of a fragment H corresponding to a fragment of a calcium binding protein excreted-secreted by adult worms of Fasciola hepatica, followed by an amino acid sequence corresponding to a unrelated protein or fragment of protein, pharmaceutical compositions, vaccines and adjuvants containing the immunogen, to a process for their preparation, another process for the production of antibodies and their use. The present invention relates to the preparation of immunogens by the addition of a peptide sequence. Thus the present invention is useful for producing an immune response, with increases in specific antibody titers in serum against proteins or other antigens and can be applied in particular for the production of specific polyclonal antibodies, immunotherapy and immunoprophylaxis.
    Type: Application
    Filed: December 10, 2009
    Publication date: December 27, 2012
    Inventors: Maria Antónia Pereira Da Conceição, Sofia Judite Marques Da Costa, António Manuel Castro, André Augusto Da Silva Almeida
  • Publication number: 20120165508
    Abstract: The invention relates to fusion proteins comprising an amino acid sequence corresponding to an H fragment or an amino acid sequence corresponding to a calcium binding protein excreted-secreted by the adult worm of Fasciola hepatica, namely the proteins Fh8 and Fh22, followed by an amino acid sequence corresponding to an unrelated protein fragment or protein, and a process for the preparation thereof and their use in recombinant protein expression systems.
    Type: Application
    Filed: December 10, 2009
    Publication date: June 28, 2012
    Inventors: Maria Antónia Pereira Da Conceição, Sofia Judite Marques Da Costa, António Manuel Oliveira Castro, André Augusto Da Silva Almeida