Abstract: The present invention relates to a method for determining if a subject suffers from Crohn's disease or from ulcerative colitis, wherein the method comprises the steps of determining if the subject suffers from inflammatory bowel disease and determining proportion of B-cells which are CD27+ in a sample from the subject. The method may further comprise determining the proportion of CD8+ T-cells which are HLA-DR+ in a sample from the subject. The present invention also relates to biomarkers for use as a marker in the diagnosis of inflammatory bowel disease, Crohn's disease ulcerative colitis. The present invention also relates to a kit for the diagnosis of Crohn's disease and/or ulcerative colitis.

Abstract: Use of a superantigen in mucosal allergen specific immune therapy (ASIT) in a non-human mammal to enhance the effect thereof. In order to enhance the effect of the mucosal ASIT, the superantigen is mucosally administered before, or with, the allergen to the non-human mammal.