Patents by Inventor Sofie GABRIELS

Sofie GABRIELS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240076387
    Abstract: The present invention provides, among other things, anti-Flt-1 antibodies and methods for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention in-cludes administering to an individual who is suffering from or susceptible to DMD an effective amount of an anti-Flt-1 antibody or antigen-binding protein thereof such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset.
    Type: Application
    Filed: November 6, 2023
    Publication date: March 7, 2024
    Inventors: Dennis KEEFE, Hans DE HAARD, Natalie DE JONGE, Sofie GABRIELS
  • Publication number: 20210206860
    Abstract: The present invention provides, among other things, anti-Flt-I antibodies and methods for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention in-cludes administering to an individual who is suffering from or susceptible to DMD an effective amount of an anti-Flt-I antibody or antigen-binding protein thereof such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset.
    Type: Application
    Filed: August 12, 2020
    Publication date: July 8, 2021
    Inventors: Dennis KEEFE, Hans DE HAARD, Natalie DE JONGE, Sofie GABRIELS
  • Patent number: 10787515
    Abstract: The present invention provides, among other things, anti-Flt-1 antibodies and methods for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of an anti-Flt-1 antibody or antigen-binding protein thereof such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: September 29, 2020
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventors: Dennis Keefe, Hans De Haard, Natalie De Jonge, Sofie Gabriels
  • Publication number: 20180072806
    Abstract: The present invention provides, among other things, anti-Flt-1 antibodies and methods for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of an anti-Flt-1 antibody or antigen-binding protein thereof such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset.
    Type: Application
    Filed: April 7, 2016
    Publication date: March 15, 2018
    Inventors: Dennis KEEFE, Hans DE HAARD, Natalie DE JONGE, Sofie GABRIELS