Patents by Inventor Sofie Kleppner

Sofie Kleppner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9278163
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: March 8, 2016
    Assignee: Titan Pharmaceuticals, Inc.
    Inventors: Rajesh A. Patel, Louis R. Bucalo, Lauren Costantini, Sofie Kleppner
  • Publication number: 20150151029
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Application
    Filed: October 3, 2014
    Publication date: June 4, 2015
    Inventors: Rajesh A. PATEL, Louis R. BUCALO, Lauren COSTANTINI, Sofie KLEPPNER
  • Patent number: 8852623
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: October 7, 2014
    Assignee: Titan Pharmaceuticals, Inc.
    Inventors: Rajesh A. Patel, Louis R. Bucalo, Lauren Costantini, Sofie Kleppner
  • Publication number: 20120258161
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Application
    Filed: June 15, 2012
    Publication date: October 11, 2012
    Inventors: Rajesh A. PATEL, Louis R. Bucalo, Lauren Costantini, Sofie Kleppner
  • Publication number: 20090162412
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Application
    Filed: December 22, 2008
    Publication date: June 25, 2009
    Inventors: Rajesh A. Patel, Louis R. Bucalo, Lauren Costantini, Sofie Kleppner
  • Publication number: 20080311171
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Application
    Filed: May 12, 2008
    Publication date: December 18, 2008
    Inventors: Rajesh A. PATEL, Louis R. Bucalo, Lauren Costantini, Sofie Kleppner
  • Publication number: 20050031667
    Abstract: The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
    Type: Application
    Filed: March 31, 2004
    Publication date: February 10, 2005
    Inventors: Rajesh Patel, Louis Bucalo, Lauren Costantini, Sofie Kleppner