Patents by Inventor Sofie Salama

Sofie Salama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for improving secondary metabolite production in fungi
    Publication number: 20090075327
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Application
    Filed: March 7, 2001
    Publication date: March 19, 2009
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • Use of sublethal concentrations of anti-invasin compounds to therapeutically or prophylactically treat fungal infections
    Patent number: 7291720
    Abstract: The invention relates to the therapeutic or prophylactic treatment of fungal infections. The invention provides new methods for therapeutically or prophylactically treating fungal infections using sub-lethal concentrations of an anti-invasin compound. The methods according to the invention have fewer toxicology problems than existing methods, and thus can be used prophylactically, as well as for early treatment for high risk patients without a firm diagnosis. The methods according to the invention can also be used to treat an established fungal infection. The invention further provides novel genes that regulate fungal hyphal growth.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: November 6, 2007
    Assignee: Microbia, Inc.
    Inventors: Brian Cali, Etchell Cordero, Peter Hecht, Todd Milne, Sofie Salama, Eric Summers, Josh Trueheart
  • Methods for improving secondary metabolite production in fungi
    Patent number: 6949356
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: September 27, 2005
    Assignee: Microbia, Inc.
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers
  • Use of sublethal concentrations of anti-invasin compounds to therapeutically or prophylactically treat fungal infections
    Publication number: 20030176367
    Abstract: The invention relates to the therapeutic or prophylactic treatment of fungal infections. The invention provides new methods for therapeutically or prophylactically treating fungal infections using sub-lethal concentrations of an anti-invasin compound. The methods according to the invention have fewer toxicology problems than existing methods, and thus can be used prophylactically, as well as for early treatment for high risk patients without a firm diagnosis. The methods according to the invention can also be used to treat an established fungal infection. The invention further provides novel genes that regulate fungal hyphal growth.
    Type: Application
    Filed: October 21, 2002
    Publication date: September 18, 2003
    Applicant: Microbia, Inc. a Delaware Corportion
    Inventors: Brian Cali, Etchell Cordero, Peter Hecht, G. Todd Milne, Sofie Salama, Eric Summers, Joshua Trueheart
  • Methods for improving secondary metabolite production in fungi
    Publication number: 20020128250
    Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.
    Type: Application
    Filed: March 7, 2001
    Publication date: September 12, 2002
    Inventors: Robert Busby, Brian Cali, Peter Hecht, Doug Holtzman, Kevin Madden, Mary Maxon, Todd Milne, Thea Norman, John Royer, Sofie Salama, Amir Sherman, Jeff Silva, Eric Summers