Patents by Inventor Sofija Andjelic

Sofija Andjelic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soluble stabilized trimeric hiv env proteins and uses thereof
    Publication number: 20110076298
    Abstract: This invention provides a protein comprising (a) a first polypeptide which comprises consecutive amino acids, the sequence of which corresponds to the sequence of a modified gp120 envelope polypeptide portion of a gp140 envelope of (i) an HIV-I KNH1144 isolate, or a quasi-species thereof, or (ii) an HIV-I 5768.4 isolate, or a quasi-species thereof; and (b) a second polypeptide which comprises consecutive amino acids, the sequence of which corresponds to the sequence of a modified gp41 ectodomain polypeptide portion of the gp140 envelope of (i) the HIV-I KNH1144 isolate or such quasi-species thereof, or (ii) the HIV-I 5768.4 isolate or such quasi-species thereof. This invention also provides nucleic acids encoding such proteins, vectors, host cells and compositions thereof. Also provided are trimeric complexes (‘trimers’) of these proteins and methods of using such trimers to combat HIV-I infection.
    Type: Application
    Filed: June 19, 2007
    Publication date: March 31, 2011
    Inventors: William C. Olson, Paul J. Maddon, Michael Franti, Sai Prasad N. Iyer, Sofija Andjelic, John P. Moore, Simon Beddows
  • Heat shock protein-based vaccines and immunotherapies
    Patent number: 7309491
    Abstract: Hybrid antigens comprising at least one antigenic domain, at least one heat shock protein binding domain, and at least one improved peptide linker there between are described which are useful for the induction of an immune response to the antigenic domain when administered alone or in a complex with at least one heat shock protein. The hybrid antigens and complexes can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: December 18, 2007
    Assignee: Antigenics Inc.
    Inventors: Paul Slusarewicz, Jessica Baker Flechtner, Sunil Mehta, Kenya Prince-Cohane, Sofija Andjelic, Brian H. Barber
  • Heat shock protein-based vaccines and immunotherapies
    Publication number: 20050214312
    Abstract: Hybrid antigens comprising at least one antigenic domain, at least one heat shock protein binding domain, and at least one improved peptide linker there between are described which are useful for the induction of an immune response to the antigenic domain when administered alone or in a complex with at least one heat shock protein. The hybrid antigens and complexes can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Application
    Filed: April 8, 2004
    Publication date: September 29, 2005
    Inventors: Jessica Flechtner, Kenya Prince-Cohane, Sunil Mehta, Paul Slusarewicz, Sofija Andjelic, Brian Barber
  • Heat shock protein-based vaccines and immunotherapies
    Publication number: 20050202033
    Abstract: Hybrid antigens comprising an antigenic domain and improved heat shock protein binding domains are described which are useful for the induction of an immune response to the antigenic domain and thus can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Application
    Filed: February 12, 2004
    Publication date: September 15, 2005
    Inventors: Jessica Flechtner, Kenya Prince-Cohane, Sunil Mehta, Paul Slusarewicz, Sofija Andjelic, Brian Barber