Abstract: A wound dressing includes a first layer located adjacent the wound and which comprises a material that is bioabsorbable, porous and adapted for serving as a scaffold for cell attachment and proliferation; and a second layer which is in contact with the first layer and which comprises an absorbent, gel forming material adapted for serving as a barrier to cell adhesion and penetration. A method of treating a wound with the dressing is also disclosed.

Abstract: The invention provides compositions and methods for increasing cell growth, stimulating cell turnover and promoting the secretion of mucus within the reproductive tract of a female mammal.

Abstract: A bandage of the type used on acute wounds, minor wounds, burn wounds and irritations, includes a first layer for covering the wound site and an area around the wound site, with the first layer including a top surface and bottom surface; a second layer over the first layer bottom surface, for absorbing exudates from the wound site; the second layer including a poly(ethyleneoxide)-based compound and a chitosan-based compound. A third layer is situated over the second layer, the third layer being of a perforated film, and wherein, at least one antimicrobial agent is associated with the bandage in a position where the antimicrobial agent will come in contact with the wound site, and which is transferable from the bandage to the wound site, upon contact with the wound site.

Abstract: The invention provides inhibitors of matrix metalloproteinases that are useful for encouraging the development of healthy skin and for treating wounds. The inhibitors are peptides having sequences related to cleavage regions of the proenzyme forms of matrix metalloproteinases. The peptide inhibitors of the invention can be formulated into therapeutic compositions, lotions, creams, skin covering and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling and ameliorate the effects of healing.

Abstract: The invention provides inhibitors of matrix metalloproteinases that are useful for encouraging the development of healthy skin and for treating wounds. The inhibitors are peptides having sequences related to cleavage regions of the proenzyme forms of matrix metalloproteinases. The peptide inhibitors of the invention can be formulated into therapeutic compositions, lotions, creams, skin covering and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling and ameliorate the effects of healing.

Abstract: An adhesive bandage of the type used on acute wounds, burn wounds, minor wounds, or irritations includes a first layer for covering the wound site and an area around the wound site. The first layer includes a top surface and bottom surface. A second adhesive layer is situated over the first layer bottom surface, for adhering the adhesive bandage to a wound site. A third absorbent layer is situated over the second layer, for absorbing exudates from the wound site. A fourth layer is situated over the third absorbent layer for allowing limited flow of exudates from the wound site to the third layer. At least one each of an antimicrobial agent and a hemostatic agent or a multifunctional wound healing agent are each associated with the adhesive bandage in a position where the agents will come in contact with the wound site.

Abstract: An apparatus, method, and computer program product for achieving interoperability between cryptographic key recovery enabled and unaware systems. The method includes the steps of encrypting data using a cryptography key to generate ciphertext; generating a key recovery block containing key recovery information for the ciphertext; determining whether a receiver for the ciphertext is key recovery unaware; and sending the key recovery block to a key recovery client when it is determined that the receiver is key recovery unaware. In a preferred embodiment, the ciphertext is sent to the receiver only after receiving confirmation from the key recovery client of the receipt of the key recovery block. Also in a preferred embodiment, the key recovery block is sent as part of an Internet Message Control Protocol (ICMP) message.

Abstract: A technique for cryptographic strength selection for at least one application is provided, in accordance with a framework for providing cryptographic support of the at least one application. Data encryption is performed at a first cryptographic strength when the at least one application is privileged to perform encryption at a first cryptographic strength. Data encryption is performed at a second cryptographic strength when the at least one application is not privileged to perform encryption at the first cryptographic strength. The first cryptographic strength is stronger than the second cryptographic strength.

Abstract: The invention provides peptides, and compositions containing those peptides, that increase the amount of fibronectin in tissue. These compositions are useful for encouraging the maintenance and development of healthy skin, for preventing and treating wrinkles, and for treating wounds. The peptides can be formulated into therapeutic compositions, lotions, creams, skin coverings and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling, and ameliorate the effects of healing.

Abstract: The present invention relates to the preparation of surface cleaning and protection compositions. A typical embodiment of this invention may be a lotion, a soap, a cream, an aerosol, a gel, a medicinal lotion, a fabric cleanser, a furniture polish, an automobile polish, and a cleanser for other solid surfaces. The use of polyhederal oligomeric silsequioxane (POSS) allows greater flexibility in delivering active agents to a surface as well as for surface protection from irritants. The current invention discloses compositions for a variety of applications ranging from skin care, home hygiene, health care, entertainment, and children training/education. The compositions may provide molecular-level benefits, form breathable protection layers on a surface (e.g. skin), provide UV protection, provide foaming effects or allow users (consumers) to know when or if the cleaning is complete.

Abstract: The invention provides compositions and methods that employ compounds that can promote skin cell renewal, wound healing, proliferation of fibroblasts and/or keratinocytes, and production of collagen or fibronectin by fibroblasts. These compositions and methods are useful for rejuvenating the skin and for treating wounds as well as gum-related and skin-related conditions.

Abstract: The invention provides compositions and methods that employ compounds that can stimulate proliferation of fibroblasts or keratinocytes and/or stimulate production of collagen by fibroblasts. These compositions and methods are useful for treating gum- and skin-related conditions.

Abstract: An Improved CDSA system (CDSA-I) includes a standard CDSA framework coupled via an Application Program Interface to an application requiring cryptographic support. During manufacture, a cryptographic control privilege is incorporated into the application, as part of an exemption mechanism, which exemption may or may not be enforced by the CDSA framework. For maximum cryptographic strength, an application must be signed by a private key controlled by the CDSA framework vendor. Inside the CDSA framework, the corresponding public key is used to verify at runtime those applications that were appropriately signed. The CDSA framework is coupled via a Service Provider Interface (SPI) to a plurality of pluggable modules for performing cryptographic operations, storing signed digital certificates for applications, and trust policies relating to cryptographic strengths. The framework is initialized to provide the cryptographic support for the application.

Abstract: The invention provides compositions and methods for conditioning the skin and reversing the effects of aging on the skin.

Abstract: Pharmaceutical compositions and methods of using the same are provided utilizing effective amounts of one or more plant growth factors, gibberellic acid, kinetin, zeatin and jasmonic acid to increase cell proliferation in various tissues and cell lines. As examples, the compositions and methods of the present invention can be used to increase proliferation of fibroblast cells and, more particularly, in the treatment of wounds as well as strengthening of the skin.

Abstract: The invention provides inhibitors of matrix metalloproteinases that are useful for encouraging the development of healthy skin and for treating wounds. The inhibitors are peptides having sequences related to cleavage regions of the proenzyme forms of matrix metalloproteinases. The peptide inhibitors of the invention can be formulated into therapeutic compositions, lotions, creams, skin covering and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling and ameliorate the effects of healing.

Abstract: The invention provides inhibitors of matrix metalloproteinases that are useful for encouraging the development of healthy skin and for treating wounds. The inhibitors are peptides having sequences related to cleavage regions of the proenzyme forms of matrix metalloproteinases. The peptide inhibitors of the invention can be formulated into therapeutic compositions, lotions, creams, skin covering and wound dressings that facilitate healing and healthy skin development, discourage scarring and wrinkling and ameliorate the effects of healing.

Abstract: Coatings are formed by applying to article a copolymer of a water soluble base polymer having graft polymerized thereto an organic moiety that includes a group that reacts with water to form a silanol group, and then curing the copolymer to form a crosslinked hydrogel coating that is absorbent, lubricious and substantially non-water soluble. Coating compositions, coated articles the subject coatings are also described.

Abstract: Pharmaceutical compositions, and methods of using the same, are provided utilizing effective amounts of one or more flavones, flavonols, flavanones, isoflavanones and isoflavones to increase cell proliferation in various tissues and cell lines. As examples, the composition and methods of the present invention can be used to increase proliferation of fibroblast cells and, more particularly, in the treatment of wounds as well as strengthening of the skin.

Abstract: An adhesive bandage of the type used on acute wounds, burn wounds, minor wounds, or irritations includes a first layer for covering the wound site and an area around the wound site. The first layer includes a top surface and bottom surface. A second adhesive layer is situated over the first layer bottom surface, for adhering the adhesive bandage to a wound site. A third absorbent layer is situated over the second layer, for absorbing exudates from the wound site. A fourth layer is situated over the third absorbent layer for allowing limited flow of exudates from the wound site to the third layer. At least one each of an antimicrobial agent and a hemostatic agent or a multifunctional wound healing agent are each associated with the adhesive bandage in a position where the agents will come in contact with the wound site.