Patents by Inventor Sohei Ito

Sohei Ito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REVERSE TRANSCRIPTASE HAVING EXCELLENT THERMAL STABILITY
    Publication number: 20250059577
    Abstract: Provided is a novel reverse transcriptase with excellent thermal stability. A reverse transcriptase comprising the following amino acid sequence: (a) an amino acid sequence having at least 75% identity with the amino acid sequence represented by SEQ ID NO: 2 or 3; or (b) an amino acid sequence having deletion, substitution, insertion, or addition of one or several amino acids in the amino acid sequence represented by SEQ ID NO: 2 or 3.
    Type: Application
    Filed: December 14, 2022
    Publication date: February 20, 2025
    Applicants: TOYOBO CO., LTD., SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION
    Inventors: Sho YOKOE, Kensuke OCHI, Shogo NAKANO, Sohei ITO
  • 2-O-sulfation enzyme mutant and 3-O-sulfation enzyme mutant, and method for using same
    Patent number: 12139728
    Abstract: The present invention provides a 2-OST mutant exhibiting a high activity.
    Type: Grant
    Filed: November 18, 2022
    Date of Patent: November 12, 2024
    Assignee: AJINOMOTO CO., INC.
    Inventors: Chihiro Tsuji, Tomoko Shimizu, Uno Tagami, Yasuhiro Mihara, Masayuki Sugiki, Shogo Nakano, Tomoharu Motoyama, Sohei Ito
  • METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE AND ENZYME USED FOR THE SAME
    Publication number: 20240191272
    Abstract: A simpler ADC production method is provided. A method for producing an antibody-drug conjugate including the following step: the step of conjugating a glycan-homogenized antibody and a glycosylated drug. The glycosylated drug consists of a drug bound to a glycan having an oxazolinated reducing end via a linker. The glycan-homogenized antibody and the glycosylated drug can be conjugated with an endo-P-N-acetylglucosaminidase mutant enzyme.
    Type: Application
    Filed: March 31, 2022
    Publication date: June 13, 2024
    Inventors: Kazuhiro HIBINO, Takashi NAGAHARA, Satoshi KANAMORI, Yutaro BABA, Hideki NARUMI, Keiichiro OHARA, Yutaka NISHIMURA, Mayu KAWASAKI, Shogo NAKANO, Sohei ITO
  • 2-O-sulfation enzyme mutant and 3-O-sulfation enzyme mutant, and method for using same
    Patent number: 11851688
    Abstract: The present invention provides a 2-OST mutant exhibiting a high activity.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: December 26, 2023
    Assignee: AJINOMOTO CO., INC.
    Inventors: Chihiro Tsuji, Tomoko Shimizu, Uno Tagami, Yasuhiro Mihara, Masayuki Sugiki, Shogo Nakano, Tomoharu Motoyama, Sohei Ito
  • NOVEL RHODOPSIN MUTANTS
    Publication number: 20230265417
    Abstract: The present disclosure provides a mutant of rhodopsin and a protein moiety thereof, nucleic acids encoding them, a cell containing any of them, and a method for culturing the cell.
    Type: Application
    Filed: October 7, 2022
    Publication date: August 24, 2023
    Applicant: SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION
    Inventors: Kiyotaka HARA, Yoko HARA, Sohei ITO, Shogo NAKANO, Yoshiki SATO, Mayu KAWASAKI, Fumio MATSUDA, Yoshihiro TOYA, Taisuke SEIKE, Kensuke OTSUKA
  • 2-O-Sulfation Enzyme Mutant and 3-O-Sulfation Enzyme Mutant, and Method for Using Same
    Publication number: 20230105158
    Abstract: The present invention provides a 2-OST mutant exhibiting a high activity.
    Type: Application
    Filed: November 18, 2022
    Publication date: April 6, 2023
    Applicant: AJINOMOTO CO., INC.
    Inventors: Chihiro Tsuji, Tomoko Shimizu, Uno Tagami, Yasuhiro Mihara, Masayuki Sugiki, Shogo Nakano, Tomoharu Motoyama, Sohei Ito
  • METHOD FOR ENZYMATICALLY PRODUCING MAYTANSINOL
    Publication number: 20230030526
    Abstract: A technique relating to a method for enzymatically producing maytansinol from an ansamitocin species, such as AP3, is provided. The method for producing maytansinol includes enzymatically producing maytansinol from an ansamitocin species with any one of various proteins.
    Type: Application
    Filed: November 27, 2020
    Publication date: February 2, 2023
    Inventors: Yutaro BABA, Kenji NISHIMURA, Yuta MIKI, Yukie KAWASAKI, Tsuyoshi YAMAMOTO, Mayu KAWASAKI, Shogo NAKANO, Sohei ITO
  • Ligase mutant
    Patent number: 11525132
    Abstract: Ligase mutants of the following (1), (2), or (3): (1) a ligase mutant comprising an amino acid sequence showing 95% or more identity to the amino acid sequence of SEQ ID NO: 1, and having a nucleic acid-linking activity; (2) a ligase mutant comprising an amino acid sequence showing 90% or more identity to the amino acid sequence of SEQ ID NO: 2, and having a nucleic acid-linking activity; or (3) a ligase mutant comprising an amino acid sequence showing 97% or more identity to the amino acid sequence of SEQ ID NO: 3, and having a nucleic acid-linking activity, have excellent properties.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: December 13, 2022
    Assignee: AJINOMOTO CO., INC.
    Inventors: Miwa Konishi, Shohei Kajimoto, Yusuke Hagiwara, Yasuhiro Mihara, Shogo Nakano, Tomoharu Motoyama, Sohei Ito
  • LIGASE MUTANT
    Publication number: 20210301280
    Abstract: Ligase mutants of the following (1), (2), or (3): (1) a ligase mutant comprising an amino acid sequence showing 95% or more identity to the amino acid sequence of SEQ ID NO: 1, and having a nucleic acid-linking activity; (2) a ligase mutant comprising an amino acid sequence showing 90% or more identity to the amino acid sequence of SEQ ID NO: 2, and having a nucleic acid-linking activity; or (3) a ligase mutant comprising an amino acid sequence showing 97% or more identity to the amino acid sequence of SEQ ID NO: 3, and having a nucleic acid-linking activity, have excellent properties.
    Type: Application
    Filed: March 23, 2021
    Publication date: September 30, 2021
    Applicant: AJINOMOTO CO., INC.
    Inventors: Miwa KONISHI, Shohei KAJIMOTO, Yusuke HAGIWARA, Yasuhiro MIHARA, Shogo NAKANO, Tomoharu MOTOYAMA, Sohei ITO
  • 2-O-Sulfation Enzyme Mutant and 3-O-Sulfation Enzyme Mutant, and Method for Using Same
    Publication number: 20200181588
    Abstract: The present invention provides a 2-OST mutant exhibiting a high activity.
    Type: Application
    Filed: February 20, 2020
    Publication date: June 11, 2020
    Applicant: AJINOMOTO CO., INC.
    Inventors: Chihiro Tsuji, Tomoko Shimizu, Uno Tagami, Yasuhiro Mihara, Masayuki Sugiki, Shogo Nakano, Tomoharu Motoyama, Sohei Ito