Patents by Inventor Soichiro Ogaki

Soichiro Ogaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing intestinal cells
    Patent number: 9376665
    Abstract: An object of the present invention is to provide a method of producing intestinal cells by use of pluripotent stem cells as a starting material. According to the present invention, provided is a method of producing intestinal cells, comprising the steps of: (A) inducing differentiation of pluripotent stem cells into definitive endoderm cells; and (B) culturing the definitive endoderm cells in the presence of (2?Z,3?E)-6-bromoindirubin-3?-oxime (BIO) and N-[(3,5-difluorophenyl)acetyl]-L-Ala-2-phenyl-L-Gly-tert-butyl-OH (DAPT) to thereby induce differentiation of the definitive endoderm cells into intestinal cells.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: June 28, 2016
    Assignees: National University Corporation Kumamoto University, LSIP, LLC
    Inventors: Shoen Kume, Soichiro Ogaki, Nobuaki Shiraki, Kazuhiko Kume
  • METHOD FOR PRODUCING INTESTINAL CELLS
    Publication number: 20140199700
    Abstract: An object of the present invention is to provide a method of producing intestinal cells by use of pluripotent stem cells as a starting material. According to the present invention, provided is a method of producing intestinal cells, comprising the steps of: (A) inducing differentiation of pluripotent stem cells into definitive endoderm cells; and (B) culturing the definitive endoderm cells in the presence of (2?Z,3?E)-6-bromoindirubin-3?-oxime (BIO) and N-[(3,5-difluorophenyl)acetyl]-L-Ala-2-phenyl-L-Gly-tert-butyl-OH (DAPT) to thereby induce differentiation of the definitive endoderm cells into intestinal cells.
    Type: Application
    Filed: October 31, 2011
    Publication date: July 17, 2014
    Applicant: LSIP, LLC
    Inventors: Shoen Kume, Soichiro Ogaki, Nobuaki Shiraki, Kazuhiko Kume