Patents by Inventor Soichiro Toda

Soichiro Toda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical modification of 2"-amino group in elsamicin a
    Patent number: 5374711
    Abstract: This invention relates to novel elsamicin A derivatives wherein the 2"-amino group is selectively modified by acylation or alkylation, a process for producing said elsamicin A derivatives, an antitumor composition containing the same as the active ingredient, and a method for therapy using said compositions.
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: December 20, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventors: Soichiro Toda, Haruhiro Yamashita, Takayuki Naito, Yuji Nishiyama
  • Compound produced by a strain of microtetraspora having antibacterial and neuritogenic activity
    Patent number: 5266588
    Abstract: Disclosed is a novel compound, designated BU-4514N, which is produced by cultivation of a novel strain of Microtetraspora, designated species T689-92. The novel compound possesses antibacterial and neuritogenic properties.
    Type: Grant
    Filed: September 25, 1992
    Date of Patent: November 30, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Soichiro Toda, Takashi Tsuno, Satoshi Yamamoto, Toshifumi Hasegawa, Osamu Tenmyo, Mary P. Rosser
  • Chemical modification of 2"-amino group in elsamicin A
    Patent number: 5237055
    Abstract: This invention relates to elsamicin A derivatives wherein the 2"-amino group is selectively modified by acylation or alkylation, a process for producing said elsamicin A derivatives, an antitumor composition containing the same as the active ingredient, and a method for therapy using said compositions.
    Type: Grant
    Filed: February 13, 1992
    Date of Patent: August 17, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Soichiro Toda, Haruhiro Yamashita, Takayuki Naito, Yuji Nishiyama
  • Chemical modification of elsamicin A at the 3' and/or 4' OH groups
    Patent number: 5229371
    Abstract: This invention relates to novel elsamicin A derivatives having an alkylidene group on the 3' and 4'-OH group or a tetrahydropyranyl group on the 4'-OH group, a process for producing said elsamicin A derivatives, antitumor composition containing the same as the active ingredient, and a method for therapy using said compositions.
    Type: Grant
    Filed: November 10, 1992
    Date of Patent: July 20, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Soichiro Toda, Haruhiro Yamashita, Takayuki Naito, Yuji Nishiyama
  • BU-4164E - A and B, prolyl endopeptidase inhibitors and their methods of use
    Patent number: 5073549
    Abstract: Disclosed herein are antibiotic BU-4164E A and B isolated from Streptomyces sp. These compounds are prolyl endopeptidase inhibitors.
    Type: Grant
    Filed: October 4, 1990
    Date of Patent: December 17, 1991
    Assignee: Bristol-Myers Squibb Company
    Inventors: Soichiro Toda, Yasutaro Hamagishi, Toshikazu Oki, Koji Tomita
  • BU-4164E - A and B, prolyl endopeptidase inhibitors
    Patent number: 4999349
    Abstract: Disclosed herein are antibiotic BU-4164E A and B isolated from Streptomyces sp. These compounds are prolyl endopeptidase inhibitors.
    Type: Grant
    Filed: March 22, 1990
    Date of Patent: March 12, 1991
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Soichiro Toda, Yasutaro Hamagishi, Toshikazu Oki, Koji Tomita
  • 1-N-(.omega.-amino-.alpha.-hydroxyalkanoyl) derivatives of 4'-deoxy-6'-N-methylkanamycin A
    Patent number: 4181797
    Abstract: 1-N-(.omega.-Amino-.alpha.-hydroxyalkanoyl) derivatives of 4'-deoxy-6'-N-methylkanamycin A are prepared by multi-step processes beginning with 1,3-ureidokanamycin A. The compounds are potent antibacterial agents.
    Type: Grant
    Filed: July 10, 1978
    Date of Patent: January 1, 1980
    Assignee: Bristol-Myers Company
    Inventors: Takayuki Naito, Susumu Nakagawa, Soichiro Toda
  • Butirosin A 3",5"-O-isopropylidene derivatives
    Patent number: 3960833
    Abstract: 3'-Deoxybutirosin A (3'-deoxyambutyrosin A), which is prepared from butirosin A, possesses an improved antibacterial spectra, especially against butirosin A resistant organisms.
    Type: Grant
    Filed: January 29, 1975
    Date of Patent: June 1, 1976
    Assignee: Bristol-Myers Company
    Inventors: Takayuki Naito, Susumu Nakagawa, Soichiro Toda