Patents by Inventor Solhee Noh

Solhee Noh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLK1 DEGRADATION INDUCING COMPOUNDS WITH INCREASED RIGIDITY
    Publication number: 20260199367
    Abstract: Novel dihydropteridone or pyrimidodiazepinone derivative based PLK1 degraders are disclosed. The present PLK1 degraders are proteolysis targeting chimeras (PROTACs) that recruit PLK1 protein into CRBN E3 ubiquitin ligase via optimized rigid linkers. The compounds may induce PLK1 degradation with improved drug properties and may be utilized for example, as a payload of antibody-drug conjugated (ADC) for the treatment of cancer.
    Type: Application
    Filed: November 29, 2023
    Publication date: July 16, 2026
    Applicant: UPPTHERA, INC.
    Inventors: Soo Hee Ryu, Seong Hoon Kim, Jun Kyu Lee, Keum Young Kang, Gibbeum Lee, Sang Youn Kim, Solhee Noh