Patents by Inventor Someet NARANG

Someet NARANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
    Publication number: 20220098282
    Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 31, 2022
    Inventors: Sanjeev AHUJA, Wai Keen CHUNG, Deborah Sweet GOLDBERG, Michael HANDLOGTEN, Someet NARANG, Brian RUSSELL, Min ZHU, Suzanne HUDAK, Kenneth HWANG, Jihong WANG
  • METHODS FOR SELECTION AND EXPANSION OF T CELLS EXPRESSING PD-1
    Publication number: 20200199567
    Abstract: The disclosure provides methods for the selection and isolation of T cells expressing programmed cell death 1 (PD-1) and for selecting a PD-1 expression level of the isolated PD-1 expressing T cells. The disclosure also provides methods of large scale expansion of selected and isolated PD-1 expressing T cells, as well as methods for treating a subject comprising administering selected and isolated PD-1 expressing T cells to the subject.
    Type: Application
    Filed: December 18, 2019
    Publication date: June 25, 2020
    Inventors: SHINO HANABUCHI, JOHN MUMM, DANIEL J. FREEMAN, JINLIN JIANG, SOMEET NARANG, RONALD HERBST, DANIELLE TOWNSLEY, GIANLUCA CARLESSO, TAEIL KIM
  • PREVENTION OF PROTEIN DISULFIDE BOND REDUCTION
    Publication number: 20190112357
    Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.
    Type: Application
    Filed: May 9, 2017
    Publication date: April 18, 2019
    Inventors: Sanjeev AHUJA, Wai Keen CHUNG, Deborah Sweet GOLDBERG, Michael HANDLOGTEN, Someet NARANG, Brian RUSSELL, Min ZHU, Suzanne HUDAK, Kenneth HWANG, Jihong WANG