Patents by Inventor Sompop Bencharit

Sompop Bencharit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystallized mammalian carboxylesterase polypeptide and screening methods employing same
    Publication number: 20030235811
    Abstract: Solved three-dimensional crystal structures of mammalian carboxylesterases (CEs) are disclosed. A solved three-dimensional crystal structure of a rabbit CE polypeptide co-crystallized with 4PP is disclosed. Solved three-dimensional structures of a human CE polypeptide co-crystallized with tacrine and a human CE polypeptide co-crystallized with homatropine are disclosed. The disclosed structures can be employed in the design of CE modulators. Methods of designing modulators of the biological activity of rabbit CE, human CE and other CE polypeptides, are also disclosed.
    Type: Application
    Filed: October 9, 2002
    Publication date: December 25, 2003
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Matthew R. Redinbo, Sompop Bencharit, Christopher L. Morton, Philip M. Potter