Patents by Inventor Son B. Le

Son B. Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Core master regulators of glioblastoma stem cells
    Patent number: 11827884
    Abstract: Provided herein are immunotherapy compositions for treating a subject with a glioblastoma, comprising a peptide formulation derived from at least one cancer or stemness factor, nanoparticles containing peptides derived from at least one cancer or stemness factor, dendritic cells containing peptides derived from at least one cancer or stemness factors, RNA coding at least one cancer or stemness factor, nanoparticles containing RNA coding at least one cancer or stemness factor, dendritic cells containing RNA coding at least one cancer factor or stemness factor, or an inhibitor of at least one cancer or stemness factor. Also provided are methods of inhibiting a glioblastoma stem-like cell (GSC), methods of treating a subject for glioblastoma, and methods of reprogramming an astrocyte to a glioblastoma stem-like cell (GSC) using such immunotherapy compositions.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: November 28, 2023
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: David Tran, Son B. Le
  • Core Master Regulators Of Glioblastoma Stem Cells
    Publication number: 20200165614
    Abstract: Provided herein are immunotherapy compositions for treating a subject with a glioblastoma, comprising a peptide formulation derived from at least one cancer or sternness factor, nanoparticles containing peptides derived from at least one cancer or sternness factor, dendritic cells containing peptides derived from at least one cancer or sternness factors, RNA coding at least one cancer or sternness factor, nanoparticles containing RNA coding at least one cancer or sternness factor, dendritic cells containing RNA coding at least one cancer factor or sternness factor, or an inhibitor of at least one cancer or sternness factor. Also provided are methods of inhibiting a glioblastoma stem-like cell (GSC), methods of treating a subject for glioblastoma, and methods of reprogramming an astrocyte to a glioblastoma stem-like cell (GSC) using such immunotherapy compositions.
    Type: Application
    Filed: May 15, 2018
    Publication date: May 28, 2020
    Inventors: David Tran, Son B. Le