Abstract: A method for integrity protection for subscribe/notify and NF discovery transactions between an NF and an NRF includes receiving, from the NF, a subscribe or discovery request message, determining that the subscribe or discovery request message includes at least one indicator requesting NRF communications integrity protection, and computing an integrity check value of at least a portion of the subscribe or discovery request message and comparing the computed integrity check value to an integrity check value included in the subscribe or discovery request message. The method further includes determining that the computed integrity check value matches the integrity check value included in the subscribe or discovery request message, and formulating a response to the subscribe or discovery request message, generating and adding at least one digital signature to the response message, and transmitting the response message to the NF.

Abstract: Aspects of the application relate to methods and compositions for delivering therapeutic nucleic acids to neural cells or tissue in a subject. Additional aspects of the application relate to therapeutic nucleic acids, for example therapeutic ribozymes, that are useful for inhibiting viral reactivation in a subject.

Abstract: The present disclosure relates to high selectivity doped hardmask films, as well as methods of providing and using such films. In particular examples, the high selectivity doped hardmask film can be employed as a hardmask, an intermediate layer, or a coverage layer.

Abstract: A computing device for collecting and preserving data acquired from various devices in a data model with the respective context of acquired data. The computing device may provide a user interface to receive the context or information model associated with a dataset. By providing data with its context, different software platforms may synthesize or analyze the retrieved data more efficiently. Moreover, the computing device may include transaction conditions to define a workflow for transferring the datasets using data model associated with one or more datasets for transmission of data to a destination. The transaction conditions may detail a custom workflow for data communication through an industrial automation system using the data model.

Abstract: The present disclosure describes various improvements for programmable nuclease-based detection assays. Also provided are compositions, methods, kits, systems, and devices for practicing the same. Such improvements include improved reporter designs to facilitate the cleavage of a reporter immobilized on a substrate by an activated programmable nuclease. Improved reporter designs may comprise various lengths and structures of the reporter. The substrate can also comprise immobilized guide nucleic acids and/or programmable nucleases.

Abstract: A method (1200) generating a three-dimensional (3D) representation of a real environment is provided. The method (1200) is performed by an apparatus (1300). The method (1200) comprises obtaining (s1202) a first image representing a first portion of the real environment, obtaining (s1204) a second image representing a second portion of the real environment, and identifying (s1206) a contour within the first image. The method also comprises identifying (s1208) a first cluster of key points from an area included within the contour, using at least some of the first cluster of key points, and identifying (s1210) a second cluster of key points included in the obtained second image.

Abstract: Methods, systems, and computer readable media for synchronization of policy data between network functions in telecommunications networks. A method includes receiving, at a first network function in a telecommunications network, a subscription request from a second network function. The subscription request specifies a subscription for updates to policy data objects maintained by the first network function. The method includes sending a notification response to the second network function. The notification response includes, for each policy data object, a custom header including a respective entity tag for the policy data object. The method includes receiving a resource request from the second network function. The resource request specifies a first policy data object and includes a first entity tag for the first policy data object. The method includes sending a synchronization result to the second network function specifying whether or not the entity tag match.

Abstract: The present invention provides mutant RSV F molecules, such as those that can be, or are stabilized, in a pre-fusion conformation by the introduction of one or more DT cross-links. The present invention also provides methods of making such mutant RSV F molecules, compositions comprising such mutant RSV F molecules, and methods of use of such mutant RSV F molecules, for example in vaccination methods, therapeutic methods, and antibody production methods.

Abstract: Methods, systems, and computer readable media for reporting a reserved load to a network function in a communications network are disclosed. One method includes determining, by a NF service producer, a current compute load metric value for the NF service producer operating in a communications network and detecting a number of active sessions supported at the NF service producer. The method further includes deriving a reserved compute load metric value corresponding to a predicted number of subsequent service requests at the NF service producer based on the number of active sessions and a predictive reserved load percentage value and calculating an adjusted reported compute load metric value amounting to a sum of the current compute load metric value and the reserved compute load metric value.

Abstract: Techniques that include a network that is configured in the first mode of a reactive mode to respond to a client attempting to access an endpoint of the network by providing information to be sent to a map server and by checking whether at least an IP address associated with the client corresponds to a registration produced for the client by a wireless controller. Further, the network is configured in a second mode of a proactive mode to determine based on a count maintained by a wireless controller of a number of client IP addresses whether to allow access or not to allow access to one or more clients to the network.

Abstract: The instant disclosure provides methods of multi-assay processing and multi-assay analysis. Such multi-assay processing and analysis pertain to automated detection of target nucleic acids, e.g., as performed in the clinical setting for diagnostic purposes. Also provided are common assay timing protocols derived from a variety of individual nucleic acid amplification and analysis protocols and modified to prevent resource contention. The instant disclosure also provides systems and devices for practicing the methods as described herein.

Abstract: A cloud node in a cloud-based system includes one or more processors and memory storing instructions that, when executed, cause the one or more processors to: communicate with a user associated with a tenant of a plurality of tenants; obtain policy and configuration for the user based on the tenant, from a central authority in the cloud-based system; provide the one or more cloud services to the user, based on the policy and configuration; and crawl one or more cloud providers having a plurality of files for the user, based on the policy and configuration. The cloud node is inline between a user device of the user and the Internet, as well as connected to the one or more cloud providers.

Abstract: An online concierge system detects acquired items included among an inventory of a customer and identifies one or more candidate available items from the acquired items based on a predicted perishability of each item and a predicted amount of each item that was used. The system retrieves recipes, matches the item(s) likely to be available to a set of recipes based on their ingredients, and identifies any remaining items for each matched recipe not likely to be available. The system retrieves a set of attributes associated with the customer and the set of recipes and computes a suggestion score for each recipe based on the attributes. The system ranks the recipes based on their scores, identifies one or more recipes for suggesting to the customer based on the ranking, and sends the recipe(s) and any remaining items for each recipe to a client device associated with the customer.

Abstract: Provided is a system for predicting a response of a user in a multi-user environment. The system includes a display engine configured to display a user interface (UI) on a display screen for inputting a message corresponding to received messages from one or more contacts, a first processing engine configured to generate a list of correlated candidate messages associated with an input message using received messages, a second processing engine configured to predict a set of correlated candidate messages relevant to the input message from the list of correlated candidate messages, and a third processing engine configured to generate a priority list of candidate messages including the predicted set of correlated candidate messages. The display engine displays, on the display screen, at least one of one or more appropriate candidate messages based on a priority associated with the appropriate candidate messages in the generated priority list of candidate messages.

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.

Abstract: Disclosed herein are lipid nanoparticles including a POEGMA-lipid conjugate that can effectively encapsulate and deliver therapeutics without the immune consequences suffered by PEG-based counterparts. An example lipid nanoparticle includes an ionizable lipid, a phospholipid, a sterol, a POEGMA-lipid conjugate, and a therapeutic. Also disclosed herein are pharmaceutical compositions that include the POEGMA-based lipid nanoparticles, methods of treating a disease or disorder, and methods of delivering a therapeutic to a cell.

Abstract: There is provided mechanisms for joint visual object detection and object mapping to a 3D model. A method is performed by an image processing device. The method includes obtaining a first sequence of digital images of a scene as captured by a first image capturing unit, and obtaining a second sequence of digital images of the scene as captured by a second image capturing unit. The second sequence of digital images is time-wise synchronized with the first sequence of digital images by being captured time-wise in parallel with the first sequence of digital images. The first image capturing unit has a narrower field of view than the field of view of the second image capturing unit. The first image capturing unit and the second image capturing unit have a known spatial relation. The method includes performing joint visual object detection and object mapping to the 3D model.

Abstract: A system for measuring a depth of a periodontal pocket defined by a gap between a tooth and gingiva includes a frame, one camera, and a processor. The frame is configured to be worn by a user. The camera is configured to capture at least one 2D image of an intraoral target area. The at least one 2D image includes a representation of at least a part of the tooth, a gingiva margin defined by a section of the gingiva adjacent to the at least a part of the tooth, and a probe tip when the probe tip is inserted into the periodontal pocket. The processor is configured to receive the captured at least one 2D image and to determine an insertion length of the probe tip in the periodontal pocket. The determined insertion length represents the depth of the periodontal pocket.

Abstract: Remote kernel execution in a heterogeneous computing system can include executing, using a device processor of a device communicatively linked to a host processor, a device runtime and receiving from the host processor within a hardware submission queue of the device, a command. The command requests execution of a software kernel and specifies a descriptor stored in a region of a memory of the device shared with the host processor. In response to receiving the command, the device runtime, as executed by the device processor, invokes a runner program associated with the software kernel. The runner program can map a physical address of the descriptor to a virtual memory address corresponding to the descriptor that is usable by the software kernel. The runner program can execute the software kernel. The software kernel can access data specified by the descriptor using the virtual memory address as provided by the runner program.