Patents by Inventor Sonali Jagdish Shah

Sonali Jagdish Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for reducing non-specific nucleic acid amplification
    Patent number: 9353393
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The disclosure generally relates to methods and kits for nucleic acid amplification of target nucleic acids of interest. The methods described herein promote the synthesis of the target nucleic acid (i.e., template nucleic acid) by reducing the production of undesirable primer-dimer structures and chimeric nucleic acid products during the amplification process by using novel modified primers.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: May 31, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Gregory Andrew Grossmann, Robert Scott Duthie, Sonali Jagdish Shah, Ryan Charles Heller
  • METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION
    Publication number: 20130210078
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The disclosure generally relates to methods and kits for nucleic acid amplification of target nucleic acids of interest. The methods described herein promote the synthesis of the target nucleic acid (i.e., template nucleic acid) by reducing the production of undesirable primer-dimer structures and chimeric nucleic acid products during the amplification process by using novel modified primers.
    Type: Application
    Filed: April 13, 2012
    Publication date: August 15, 2013
    Applicant: General Electric Company
    Inventors: John Richard Nelson, Gregory Andrew Grossmann, Robert Scott Duthie, Sonali Jagdish Shah, Ryan Charles Heller
  • Methods and kits for reducing non-specific nucleic acid amplification
    Patent number: 8507662
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: August 13, 2013
    Assignee: General Electric Company
    Inventors: John Richard Nelson, Robert Scott Duthie, Sonali Jagdish Shah, Clifford Leslie Smith
  • METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION
    Publication number: 20110287510
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.
    Type: Application
    Filed: July 15, 2011
    Publication date: November 24, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Robert Scott Duthie, Sonali Jagdish Shah, Clifford Leslie Smith
  • Methods and kits for reducing non-specific nucleic acid amplification
    Patent number: 7993839
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: August 9, 2011
    Assignee: General Electric Company
    Inventors: John Richard Nelson, Robert Scott Duthie, Sonali Jagdish Shah, Clifford Leslie Smith
  • METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION
    Publication number: 20090130720
    Abstract: Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.
    Type: Application
    Filed: December 18, 2008
    Publication date: May 21, 2009
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: John Richard Nelson, Robert Scott Duthie, Sonali Jagdish Shah, Clifford Leslie Smith