Abstract: The present disclosure provides a P450 cytochrome enzyme for andrographolide synthesis and its application, belonging to the field of bioengineering. The present disclosure uses Saccharomyces cerevisiae CEN.PK2-1D as a host, and implements knockout of ROX1 and GAL80 genes on the genome, and integrative expression of GGPP synthase encoding gene and CPS diterpene synthase encoding gene at ROX1 site; and implements free expression of ApCPR and CYP71A8 and CYP71D10 both with truncated signal peptides, successfully constructing recombinant S. cerevisiae, and achieving de novo synthesis of 3,15,19-Trihydroxy-8(17),13-ent-labdadiene-16-oic acid. Compared with the blank, a response value of a product peak reaches 1.9*106, and this strategy provides necessary reference for analyzing biosynthetic pathway of andrographolide and using metabolic engineering to synthesize andrographolide and related derivatives thereof.

Abstract: A water treatment composition is disclosed herein comprising a nonylphenol resin and a polyethoxylated tallow amine.

Abstract: A folding device is provided. The folding device includes a bearing and fixing mechanism (1) configured to bear and fix a main body portion (21) of a to-be-folded device (2); a folding mechanism (3) located on at least one side of the bearing and fixing mechanism (1), the folding mechanism (3) being rotatably connected to the bearing and fixing mechanism (1) and configured to bear and fix a to-be-folded portion (22) of the to-be-folded device (2); and a driving mechanism (4) connected to the folding mechanism (3), the driving mechanism (4) being configured to drive the folding mechanism (3) to turn relative to the bearing and fixing mechanism (1), so as to fold the to-be-folded portion (22) to a side in a thickness direction of the main body portion (21). The folding device can fold automatically, and manual folding is avoided.

Abstract: A double patterning method of manufacturing select gates and word lines is provided in the present invention, including forming first string patterns composed of word line patterns and select gate patterns on a target layer, forming a conformal spacer layer on first string patterns, wherein the spacer layer forms trenches between first string patterns, forming a fill layer filling up the trenches on the spacer layer, removing fill layer outside of the trenches, so that fill layer in the trenches forms second string patterns, wherein the second string patterns and the first string patterns are spaced apart, removing exposed spacer layer, so that the first string patterns and the second string patterns constitute target patterns spaced apart from each other on the target layer, and performing an etching process using those target patterns as a mask to remove exposed target layer, so as to form word lines and select gates.

Abstract: Provided is a method for the non-invasive detection of fetal genetic variations, comprising: firstly, estimating the percentage of fetal genetic material in a plasma sample of a pregnant woman by means of carrying out targeted sequencing on polymorphic sites on a reference genome and then performing allelic copy counting for each polymorphic site; and then, carrying out allelic copy counting on the polymorphic sites on a target genome or a target to be detected, and using a goodness-of-fit test or a relative distribution diagram of allele counts to detect whether the target to be detected in the sample has any variation at the chromosomal level, sub-chromosomal level or single genetic site level. The method is suitable for simultaneously detecting chromosomal euploidy variations, micro-deletion and micro-duplication variations at the sub-chromosomal level and variations at the short sequence level in the plasma sample of the pregnant woman, and has good development and application prospects.

Abstract: The disclosure discloses construction of recombinant Saccharomyces cerevisiae for synthesizing carminic acid and application thereof and belongs to the technical field of genetic engineering and bioengineering. The disclosure obtains recombinant S. cerevisiae CA-B2 capable of synthesizing carminic acid by heterologously expressing cyclase Zhul, aromatase ZhuJ, OKS of Octaketide synthase 1, C-glucosyltransferase UGT2, monooxygenase aptC and 4?-phosphopantetheinyl transferase npgA in S. cerevisiae. The recombinant S. cerevisiae can be used for synthesizing carminic acid by taking self-synthesized acetyl-CoA and malonyl-CoA as a precursor. On this basis, OKS, cyclase, aromatase, C-glucosyltransferase and monooxygenase relevant to carminic acid are integrated to a high copy site, which can remarkably improve the yield of carminic acid. The yield of carminic acid can be increased to 2664.6 ?g/L by optimizing fermentation conditions, and the fermentation time is shortened significantly.

Abstract: A method for predicting an air quality index (AQI) based on a fusion model proposes a differential fusion seasonal prediction model (DF-SPM) based on a random forest (RF) model and a convolutional neural network (CNN)-long short-term memory (LSTM)-attention (CLA) model. This method uses the optimal threshold interval (OTI) search algorithm to search and learn the OTI of four seasons during the prediction process, and obtains the final prediction results according to the predicted values of RF model and CLA model. The fusion model combines the prediction advantages of two independent models, and fully considers the seasonal and periodic characteristics of AQI, so as to accurately search OTI in different time periods with the seasonal scale, so as to achieve higher prediction accuracy. The OTI strategy of fusion model is superior to the single threshold strategy, which can extract the historical fluctuation characteristics of AQI and achieve higher prediction accuracy.

Abstract: Technologies for specialty chemical development and testing include devices and methods for receiving a test description. The test description is indicative of test parameters for a test of a chemical formulation, which may be an oil field specialty chemical. The devices and methods may include searching a database of historical test results based on similarity to the test parameters to generate multiple candidate chemical formulations. The devices and methods may cluster the candidate chemical formulations with an unsupervised machine learning algorithm to select a representative chemical formulation for each cluster. The devices and methods may include training a predictor based on test results using a supervised machine learning algorithm. Multiple virtual formulations may be generated and performances of each virtual formulation may be predicted with the predictor. Other embodiments are described and claimed.

Abstract: A gas turbine power generation device includes: an inlet pipe (1), a compressor (2), an air storage compartment (3), a compressor rotor (4), a compressor gear shift (6), a compressor exhaust pipeline (8), a combustion chamber intake pipeline (10), a combustion chamber intake cone (11), a combustion chamber pneumatic valve (14), a spark plug (19), a combustion chamber (21), a Tesla turbine (22), a gas collection compartment (27), an outlet pipe (28), a turbine rotor (30), a generator gear shift (32) and a generator (33).

Abstract: The disclosure discloses construction of recombinant Saccharomyces cerevisiae for synthesizing carminic acid and application thereof and belongs to the technical field of genetic engineering and bioengineering. The disclosure obtains recombinant S. cerevisiae CA-B2 capable of synthesizing carminic acid by heterologously expressing cyclase Zhul, aromatase ZhuJ, OKS of Octaketide synthase 1, C-glucosyltransferase UGT2, monooxygenase aptC and 4?-phosphopantetheinyl transferase npgA in S. cerevisiae. The recombinant S. cerevisiae can be used for synthesizing carminic acid by taking self-synthesized acetyl-CoA and malonyl-CoA as a precursor. On this basis, OKS, cyclase, aromatase, C-glucosyltransferase and monooxygenase relevant to carminic acid are integrated to a high copy site, which can remarkably improve the yield of carminic acid. The yield of carminic acid can be increased to 2664.6 µg/L by optimizing fermentation conditions, and the fermentation time is shortened significantly.

Abstract: A device for clock control and related products are provided. The device includes a voltage detecting unit and a clock stretching unit. The voltage detecting unit is configured to detect a supply voltage at a target position in the processor, and output a voltage-alarm signal when the supply voltage is lower than or equal to a preset first threshold. The clock stretching unit is connected with the voltage detecting unit and configured to generate a second clock signal according to a first clock signal having a reference frequency in response to reception of the voltage-alarm signal, such that the processor uses the second clock signal to perform data processing. A frequency of the second clock signal is lower than the reference frequency.

Abstract: One-part condensation curable silyl-modified polymer (SMP) based sealant compositions in particular one-part condensation curable SMP based sealant compositions containing a catalyst comprising (i) a titanate and/or zirconate and (ii) a metal carboxylate salt which compositions upon cure provide elastomeric sealants having low modulus and a high elastic recovery.

Abstract: An anti-corrosive concrete grouting material for coastal structure connection and a method for preparing the same, belonging to the technical field of anti-corrosion of coastal assembled structure connectors. The grouting material includes the following components: expansible compound cement, slag sand, fly ash (FA), polyvinyl alcohol (PVA) (containing an oxidant and a catalyst), graphene oxide (GO), a water reducer, an adjusting admixture, a defoaming agent, a mineral admixture and water.

Abstract: The present invention provides a chip integration module, including a die, a passive device, and a connecting piece, where the die is provided with a die bonding portion, the passive device is provided with a passive device bonding portion, the die bonding portion of the die and the passive device bonding portion of the passive device are disposed opposite to each other, and the connecting piece is disposed between the die bonding portion and the passive device bonding portion and is connected to the die bonding portion and the passive device bonding portion. The chip integration module of the present invention achieves easy integration and has low costs. Moreover, a path connecting the die to the passive device becomes shorter, which can improve performance of the passive device. The present invention further discloses a chip package structure and a chip integration method.

Abstract: A gas turbine power generation device includes: an inlet pipe (1), a compressor (2), an air storage compartment (3), a compressor rotor (4), a compressor gear shift (6), a compressor exhaust pipeline (8), a combustion chamber intake pipeline (10), a combustion chamber intake cone (11), a combustion chamber pneumatic valve (14), a spark plug (19), a combustion chamber (21), a Tesla turbine (22), a gas collection compartment (27), an outlet pipe (28), a turbine rotor (30), a generator gear shift (32) and a generator (33).

Abstract: A dry low NOX staged combustion system includes a fuel nozzle and a combustion compartment. The fuel nozzle includes a purge gas tube, a diffusion combustion fuel tube, an isolation gas tube, a premixed combustion fuel tube, a premixed combustion air tube. The purge gas tube is configured to feed a purge gas. The diffusion combustion fuel tube is fitted over the purge gas tube, and having an end provided with a diffusion combustion fuel swirler. The isolation gas tube is fitted over the diffusion combustion fuel tube. The premixed combustion fuel tube is fitted over the isolation gas tube. The premixed combustion air tube is fitted over the premixed combustion fuel tube. The combustion compartment is located downstream of the fuel nozzle.

Abstract: The invention discloses a semi-airborne time domain electromagnetic exploration system for an unmanned aerial vehicle, and belongs to the technical field of geophysical electromagnetic exploration. The system comprises a ground high-power electromagnetic field source emission subsystem, a semi-airborne time domain electromagnetic exploration and observation subsystem and a data processing interpretation software subsystem, wherein the ground high-power electromagnetic field source emission subsystem comprises an IGBT full bridge, a PWM control circuit, a rectification filter circuit and a protection circuit; the semi-airborne time domain electromagnetic exploration and observation subsystem comprises an unmanned aerial vehicle, a receiving coil and a receiver; the data processing interpretation software subsystem comprises a system function module and a bottom layer supporting module, and the bottom layer supporting module is used for providing a universal performance function for the system function module.

Abstract: The disclosure is about a method capable of realizing the preparation and in-situ separation of the oligomeric ricinoleate, which uses the ricinoleic acid as raw material, and uses a protonic acid-type ionic liquid as a catalyst to cause the dehydration and esterification reactions between ricinoleic acid molecules. By continuously distilling out the generated water under a reduced pressure, the oligomeric ricinoleate with a polymerization degree of 2 to 10 is obtained. After the reaction, a method of washing with water or static stratification is selected to recover the catalyst according to the miscibility of the catalyst and reaction system. In his disclosure, renewable raw materials are used, the process is clean and pollution-free, and the operation is simple.

Abstract: A nano-modified material for cavity wall with insulation for prefabricated building, preparation method and application thereof, belonging to the technical field of building materials. The material includes splicing structures and a nano-modified silane waterproof coating, wherein the splicing structure includes a recycled concrete structure layer and a nano-modified foam concrete thermal insulation core layer, the recycled concrete structure layer is a hollow cuboid structure with openings at both ends, the nano-modified foam concrete thermal insulation core layer is a structure formed by casting inside the recycled concrete structure layer, and the nano-modified silane waterproof coating is applied at a butt joint of two of the splicing structures.

Abstract: A remote-controlled gasoline cleaner including a main unit, sprayer, and remote control. The main unit includes a controller, start switch device, stop switch device, and gasoline engine start/stop apparatus. The remote control sends a start remote control signal or stop remote control signal to the main unit. The controller controls the start switch device in response to the start remote control signal received, and controls the stop switch device in response to the stop remote control signal received. The start switch device receives a start command of the controller to connect to a power supply circuit of a starter motor in the gasoline engine start/stop apparatus. The starter motor starts a gasoline engine. The stop switch device receives a stop command of the controller to connect to a short circuit of an ignition coil in the gasoline engine start/stop apparatus, thereby blowing out the gasoline engine.