Abstract: Disclosed herein is a pouch-type secondary battery and a manufacturing method thereof including. The pouch-type secondary battery includes an electrode assembly; an electrode lead extending from an electrode tab of the electrode assembly; an upper pouch; and a lower pouch. The upper pouch and the lower pouch include a sealed area where the edges are sealed and an unsealed area. An average thickness of the sealed area of the upper pouch and an average thickness of the sealed area of the lower pouch are equal to each other, and the average thickness of the unsealed area of the upper pouch is smaller than the average thickness of the unsealed area of the lower pouch, so that even if the thickness of the lower pouch is reduced during the sealing process of heat-sealing, the sealed area of the upper and lower pouches are formed with little difference in thickness.

Abstract: A positive electrode active material for a secondary battery includes a lithium composite transition metal oxide including nickel (Ni), cobalt (Co), and manganese (Mn), wherein the lithium composite transition metal oxide has a layered crystal structure of space group R3m, includes the nickel (Ni) in an amount of 60 mol % or less based on a total amount of transition metals, includes the cobalt (Co) in an amount greater than an amount of the manganese (Mn), and is composed of single particles.

Abstract: Provided is yarn for a cell culture scaffold. The yarn for a cell culture scaffold according to an exemplary embodiment of the present invention includes slitting yarn produced by cutting a compressed nanofiber web to a predetermined width. Accordingly, by creating microenvironments suitable for migration, proliferation and differentiation of cells, cell viability may be enhanced and cells may be three-dimensionally proliferated. In addition, a scaffold according to the present invention has a mechanical strength sufficient for prevention of disruption of the scaffold which occurs during cell culture, such that cells may be stably proliferated. Further, the scaffold according to the present invention uses slitting yarn formed of the compressed nanofiber web, thereby having pores with various sizes, and therefore cell proliferation and cell viability may be enhanced by creation of an extracellular matrix-like environment.

Abstract: The present disclosure provides a compound of a chemical structure having the ability of inhibiting or disintegrating an androgen receptor (AR), or a pharmaceutically acceptable salt of the compound. The present disclosure also provides a composition comprising such a compound or a pharmaceutically acceptable salt thereof. The present disclosure provides a pharmaceutical use of a compound according to the present disclosure, a salt thereof, and a composition comprising same for the treatment or prevention of AR-related diseases. The present disclosure also provides a method for treating or preventing AR-related diseases, comprising administering to a subject in need of treatment an effective amount of a compound according to the present disclosure, a salt thereof, or a composition comprising same.

Abstract: The present disclosure provides a compound having a specific chemical structure or a pharmaceutically acceptable salt thereof having activity of degrading androgen receptor (AR). The present disclosure also provides a composition comprising such a compound or a pharmaceutically acceptable salt thereof. The present disclosure also provides a medical use of a compound according to the present disclosure, a salt thereof, and a composition comprising the same for the treatment or prophylaxis of AR-related diseases. The present disclosure also provides a method for treating or preventing an AR-related disease comprising administering to a subject in need thereof an effective amount of a compound according to the present disclosure, a salt thereof, or a composition comprising the same.

Abstract: Antiviral polypeptides and methods of use are provided herein. In particular, these polypeptides can comprise the Yodha amino acid sequence, variants, derivatives, or truncated versions thereof. In certain embodiments, this disclosure relates to uses of the peptides, nucleic acid molecules, and compositions disclosed herein to treat or prevent a viral infection.

Abstract: The present disclosure relates to a perovskite light-emitting composition, and a method for preparing the same. The method for producing the perovskite light-emitting composition of the present disclosure includes an organic siloxane solvent having very high hydrophobicity and low surface tension as a synthesis solvent, thereby having a large surface tension difference from the perovskite light-emitting particles containing an organic ligand. Through these properties, a dense organic ligand can be attached to the surface of the perovskite nanoparticles, and perovskite light-emitting particles having a high ligand density can be prepared. Accordingly, the perovskite light-emitting particles prepared by the method of the present disclosure have improved dispersion stability, light-emitting properties and long-term storage stability.

Abstract: Provided are nanocellulose composite and preparation method thereof. The method comprises preparing cellulose nanofiber, mixing the cellulose nanofiber with a silica precursor in a solvent to attach silica particles to the surface of the cellulose nanofiber, or to form a silica coating layer on the surface of the cellulose nanofiber, and mixing the cellulose nanofiber with the silica particles or the silica coating layer with a polymer. According to the present invention, by using surface vitrification-treated nano cellulose, nanocellulose polymer composites that exhibits high mechanical properties such as impact resistance as well as excellent heat resistance can be prepared.

Abstract: Antiviral polypeptides and methods of use are provided herein. In particular, these polypeptides can comprise the Yodha amino acid sequence, variants, derivatives, or truncated versions thereof. In certain embodiments, this disclosure relates to uses of the peptides, nucleic acid molecules, and compositions disclosed herein to treat or prevent a viral infection.

Abstract: Antiviral polypeptides and methods of use are provided herein. In particular, these polypeptides can comprise the Yodha amino acid sequence, variants, derivatives, or truncated versions thereof. In certain embodiments, this disclosure relates to uses of the peptides and compositions disclosed herein to treat or prevent a viral infection.

Abstract: Provided are nanocellulose composite and preparation method thereof. The method comprises preparing cellulose nanofiber, mixing the cellulose nanofiber with a silica precursor in a solvent to attach silica particles to the surface of the cellulose nanofiber, or to form a silica coating layer on the surface of the cellulose nanofiber, and mixing the cellulose nanofiber with the silica particles or the silica coating layer with a polymer. According to the present invention, by using surface vitrification-treated nano cellulose, nanocellulose polymer composites that exhibits high mechanical properties such as impact resistance as well as excellent heat resistance can be prepared.

Abstract: It has been discovered that certain peptides are useful for managing certain viral infections. Thus, this disclosure relates to the use of peptides reported herein for the prevention or treatment of viral infections such as influenza infections. In certain embodiments, this disclosure relates to peptides, variants, or derivatives having sequences disclosed herein and pharmaceutical compositions comprising the same.

Abstract: Antiviral polypeptides and methods of use are provided herein. In particular, these polypeptides can comprise the Yodha amino acid sequence, variants, derivatives, or truncated versions thereof. In certain embodiments, this disclosure relates to uses of the peptides and compositions disclosed herein to treat or prevent a viral infection.

Abstract: Disclosed are a system and method for providing search results. The system for providing search results comprises: a keyword-receiving unit which receives a keyword from a user; an exposure-order-applying unit which applies, to a collection search bar, the order of exposure of a collection containing a listing of keyword search results; and a search-result-providing unit which provides the user with a webpage of the keyword search results, said webpage containing the collection search bar.

Abstract: The present invention relates to a method for the toxicity assessment of nano-materials, and more specifically, it is relates to an objective, reproducible and accurate assessment method for the unbiased toxicity testings of nano-materials, which minimize artifacts of the conventional methods for the toxicity assessment of the nano-materials by considering the dose characteristics of the nano-material itself using Selective multi-Plane Illumination Microcopy (SPIM); and the response characteristics of the nano-material using the improved or novel cellular responses assessment methods for nano-materials (e.g., modified MTT assay using image cytometric analysis, normal-inverted exposure apparatus, and modified flow cytometry), and a system and an apparatus thereof.

Abstract: Disclosed are a system and method for providing search results. The system for providing search results comprises: a keyword-receiving unit which receives a keyword from a user; an exposure-order-applying unit which applies, to a collection search bar, the order of exposure of a collection containing a listing of keyword search results; and a search-result-providing unit which provides the user with a webpage of the keyword search results, said webpage containing the collection search bar.

Abstract: The present invention relates to a method for the toxicity assessment of nano-materials, and more specifically, it is relates to an objective, reproducible and accurate assessment method for the unbiased toxicity testings of nano-materials, which minimize artifacts of the conventional methods for the toxicity assessment of the nano-materials by considering the dose characteristics of the nano-material itself using Selective multi-Plane Illumination Microcopy (SPIM); and the response characteristics of the nano-material using the improved or novel cellular responses assessment methods for nano-materials (e.g., modified MTT assay using image cytometric analysis, normal-inverted exposure apparatus, and modified flow cytometry), and a system and an apparatus thereof.

Abstract: A novel use of GRP 94 in treatment of virus infection is provided. More specifically, a method of inhibiting virus infection by inhibiting expression of GRP 94 and/or inactivating activity of GRP 94, and a method of developing drugs for preventing and/or treating virus infection and/or diseases caused by virus infection by using GRP 94 as a target are provided.

Abstract: A novel use of GRP 94 in treatment of virus infection is provided. More specifically, a method of inhibiting virus infection by inhibiting expression of GRP 94 and/or inactivating activity of GRP 94, and a method of developing drugs for preventing and/or treating virus infection and/or diseases caused by virus infection by using GRP 94 as a target are provided.