Patents by Inventor Songbai CAI

Songbai CAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UNIVERSAL CHIMERIC ANTIGEN RECEPTOR T-CELL PREPARATION TECHNIQUE
    Publication number: 20230265154
    Abstract: Provided are a universal chimeric antigen receptor (CAR) T cell and preparation method and application thereof. The binding of the cell HLA-A/HLA-B to the TCR is inhibited; the TCR gene expression is silenced; the invention man be used for allogeneic tumor treatment and does not cause GVHD and HVG reaction during allogeneic infusion, and thus improves the survival and antineoplastic effect of allogeneic CAR-T cells in the receptor.
    Type: Application
    Filed: September 6, 2018
    Publication date: August 24, 2023
    Inventors: Xinxin WANG, Zhongdong SHI, Liping LIU, Chunhui YANG, Jing SUN, Songbai CAI, Wei CAO
  • COMPOSITION FOR TREATING ARTICULAR CARTILAGE DEFECTS
    Publication number: 20180117088
    Abstract: A composition for treating articular cartilage defects, and a manufacturing method, and a kit thereof, the composition comprising: a therapeutically effective amount of fat-derived mesenchymal progenitor cells, serum albumin solution, and sodium hyaluronate, Above 95% of the fat-derived mesenchymal progenitor cells have the surface antigen CD90, CD73, CD29, and CD49d, and express cytokines selected from TGF-?1, HGF, and VEGF. The composition has the effect of treating articular cartilage defects.
    Type: Application
    Filed: March 10, 2016
    Publication date: May 3, 2018
    Inventors: Wei CAO, Wen WANG, Meng LI, Chengxiang DAI, Li ZHANG, Luyi ZHANG, Fei WANG, Suke LI, Jia LIU, Songbai CAI