Patents by Inventor Sonia Kerrad

Sonia Kerrad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulphones which modulate the action of gamma-secretase
    Patent number: 7598386
    Abstract: Novel sulphones of Formula I are disclosed: wherein A completes a 4-7 membered ring optionally comprising up to two heteroatoms. The compounds modulate the action of ?-secretase and are therefore useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: October 6, 2009
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Jose Luis Castro Pineiro, Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Andrew Pate Owens, Duncan Edward Shaw, Martin Richard Teall, Susannah William, Brian John Williams
  • Sulphones which modulate the action of gamma secretase
    Patent number: 7595344
    Abstract: Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: September 29, 2009
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Jose Luis Castro Pineiro, Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Andrew Pate Owens, Duncan Edward Shaw, Martin Richard Teall, Susannah William, Brian John Williams
  • Sulphones which modulate the action of gamma secretase
    Publication number: 20090131419
    Abstract: Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: May 6, 2008
    Publication date: May 21, 2009
    Inventors: Jose Luis Castro Pineiro, Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Andrew Pate Owens, Duncan Edward Shaw, Martin Richard Teall, Susannah William, Brian John Williams
  • Novel cyclohexyl sulphones
    Publication number: 20080045533
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 21, 2008
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan Nadin, Paul Oakley, Duncan Shaw, Martin Teall, Susannah Williams, Brian Williams
  • Cyclohexyl sulphones
    Patent number: 7304094
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: December 4, 2007
    Assignee: Merck Sharp + Dohme
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams, Brian John Williams
  • Sulphones which modulate the action of gammasecretase
    Publication number: 20070213329
    Abstract: Novel sulphones of Formula I are disclosed: wherein A completes a 4-7 membered ring optionally comprising up to two heteroatoms. The compounds modulate the action of ?-secretase and are therefore useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: April 23, 2007
    Publication date: September 13, 2007
    Inventors: Jose Castro Pineiro, Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan Nadin, Paul Oakley, Andrew Owens, Duncan Shaw, Martin Teall, Susannah Williams, Brian Williams
  • Cyclohexyl sulphone derivatives as gamma-secretase inhibitors
    Patent number: 7101895
    Abstract: Compounds of formula I: wherein Ar1 and Ar2 are optionally substituted aryl or heteroaryl, L is a bond, ?CH— or —(CHRa)n—, and X is SCN, SR1, S(O)R1, (CRaRb)mSO2R1, SO2N(R2)2, SO2NHCOR1, SO2NHN(R2)2, OSO2N(R2)2, OS(O)N(R2)2, OSO2NHCOR1, COR4, NHCOR1, NHCO2R1, NHCON(R2)2, NHSO2R1 or NHSO2N(R2)2, inhibit the processing of APP by gamma secretase, and hence are useful in treatment of Alzheimer's disease.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: September 5, 2006
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Ian Churcher, Timothy Harrison, Sonia Kerrad, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams
  • Novel cyclohexyl sulphones
    Publication number: 20060041020
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: October 28, 2005
    Publication date: February 23, 2006
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan Nadin, Paul Oakley, Duncan Shaw, Martin Teall, Susannah Williams, Brian Williams
  • Cyclohexyl sulphones
    Patent number: 6984663
    Abstract: Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: January 10, 2006
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams, Brian John Williams
  • Cyclohexyl sulphones as gamma-secretase inhibitors
    Patent number: 6890956
    Abstract: Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: May 10, 2005
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Ian Churcher, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Andrew Pate Owens, Duncan Edward Shaw, Joanne Thomson, Susannah Williams
  • Cyclohexyl sulphones as gamma-secretase inhibitors
    Publication number: 20040121995
    Abstract: Compounds of formula I: 1
    Type: Application
    Filed: October 6, 2003
    Publication date: June 24, 2004
    Inventors: Ian Churcher, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Andrew Pate Owens, Duncan Edward Shaw, Joanne Thomson, Susannah Williams
  • Cyclohexyl sulphone derivatives as gamma-secretase inhibitors
    Publication number: 20040122050
    Abstract: Compounds of formula I: 1
    Type: Application
    Filed: October 6, 2003
    Publication date: June 24, 2004
    Inventors: Ian Churcher, Timothy Harrison, Sonia Kerrad, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams
  • Sulphones which modulate the action of gamma secretase
    Publication number: 20040116404
    Abstract: Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.
    Type: Application
    Filed: October 1, 2003
    Publication date: June 17, 2004
    Inventors: Jose Luis Castro Pineiro, Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Andrew Pate Owens, Duncan Edward Shaw, Martin Richard Teall, Susannah William, Brian John Williams
  • Novel cyclohexyl sulphones
    Publication number: 20030114496
    Abstract: Novel sulphones of formula I are disclosed: 1
    Type: Application
    Filed: August 20, 2002
    Publication date: June 19, 2003
    Inventors: Ian Churcher, Kevin Dinnell, Timothy Harrison, Sonia Kerrad, Alan John Nadin, Paul Joseph Oakley, Duncan Edward Shaw, Martin Richard Teall, Susannah Williams, Brian John Williams