Patents by Inventor Sonia Maffioli

Sonia Maffioli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lantipeptide
    Patent number: 10487124
    Abstract: The present invention concerns novel lantipeptide (lanthionine-containing peptide) compounds having general formula (I), a process for their preparation, the key intermediates in said processes, their pharmaceutical acceptable salts and pharmaceutical compositions containing them, as well as their use in the treatment of pain.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: November 26, 2019
    Assignees: NAICONS S.r.l., FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
    Inventors: Marianna Iorio, Sonia Maffioli, Paolo Monciardini, Margherita Sosio, Stefano Donadio, Rosalia Bertorelli, Oscar Sasso, Angelo Reggiani
  • NOVEL LANTIPEPTIDE
    Publication number: 20150291670
    Abstract: The present invention concerns novel lantipeptide (lanthionine-containing peptide) compounds having general formula (I), a process for their preparation, the key intermediates in said processes, their pharmaceutical acceptable salts and pharmaceutical compositions containing them, as well as their use in the treatment of pain.
    Type: Application
    Filed: July 12, 2012
    Publication date: October 15, 2015
    Inventors: Marianna Iorio, Sonia Maffioli, Paolo Monciardini, Margherita Sosio, Stefano Donadio, Rosalia Bertorelli, Oscar Sasso, Angelo Reggiani
  • PSEUDOURIDIMYCIN (PUM) AND ITS DERIVATIVES
    Publication number: 20150210740
    Abstract: The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts thereof, a process for the preparation thereof, as well as pharmaceutical compositions containing them and the use thereof as drugs, particularly for the treatment of infectious diseases.
    Type: Application
    Filed: July 5, 2013
    Publication date: July 30, 2015
    Inventors: Sonia Maffioli, Gianpaolo Candiani, Paola Guglierame, Paolo Monciardini, Stefania Serina, Stefano Donadio
  • Process for the production of ramoplanin-like amide derivatives
    Patent number: 7169890
    Abstract: The invention regards a process for the production of ramoplanin-like derivatives of formula (I): RAMO-NC—CO—R (I), wherein the radical R represents a hydrocarbon radical and the portion RAMO-NH— represents deacylated ramoplanin, any of its factors or ramoplanose. The compound of Formula (I) are obtained by reacting a carboxylic acid R—COOH with deacylated ramoplanin, any of its factors or ramoplanose protected on the ornitine amino groups. New compounds wherein the hydrocarbon radical R is different form those characaterizing the ramoplanin and ramoplanose natural products and their tetrahydro-derivatives are calimed. The new compounds have the same or better antinfective activity, lower haemolytic effect and better tolerability profile than ramoplanin.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: January 30, 2007
    Assignee: Vicuron Pharmaceuticals Inc.
    Inventors: Romeo Ciabatti, Sonia Maffioli, Anna Checchia, Gabriella Romano, Gianpaolo Candiani, Gianbattista Panzone
  • Ramoplanin derivatives possessing antibacterial activity
    Publication number: 20060211603
    Abstract: Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
    Type: Application
    Filed: August 4, 2005
    Publication date: September 21, 2006
    Applicant: VICURON PHARMACEUTICALS INC.
    Inventors: Bore Raju, Romeo Ciabatti, Sonia Maffioli, Upinder Singh, Gabriella Romano, Elena Michelucci, Paolo Tiseni, Gianpaolo Candiani, Bum Kim, Hardwin O'Dowd