Patents by Inventor Sonja Hess

Sonja Hess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10266866
    Abstract: A method for preparing a methionine containing peptide or protein for analysis by mass spectrometry by incubating the methionine containing peptide or protein with a heterologous methionine sulfoxide reductase A (MsrA), a heterologous methionine sulfoxide reductase B (MsrB), or a heterologous methionine sulfoxide reductase AB (MsrAB) enzyme results in the reduction of an oxidized methionine containing peptide or protein.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: April 23, 2019
    Assignee: California Institute of Technology
    Inventors: Michael Sweredoski, Annie Moradian, Tanya R. Yakushi, Sonja Hess, Roxana Eggleston-Rangel
  • Publication number: 20170152541
    Abstract: A method for preparing a methionine-containing peptide or protein for analysis by mass spectrometry includes incubating the methionine-containing peptide or protein with a heterologous methionine sulfoxide reductase A (MsrA), MsrB, or MsrAB enzyme resulting in the reduction of oxidized methionine-containing peptides or proteins.
    Type: Application
    Filed: November 23, 2016
    Publication date: June 1, 2017
    Inventors: Michael Sweredoski, Annie Moradian, Tanya R. Yakushi, Sonja Hess, Roxana Eggleston-Rangel
  • Patent number: 7759643
    Abstract: A single electrode electrochemical/electrospray ionization source using a corona discharge and a method of analyzing a sample using a corona discharge single electrode electrochemical/electrospray ionization source are provided. In the corona discharge single electrode electrochemical/electrospray ionization technique electrons are removed from the metal tip of the device through gases present in the electrospray ion source resulting in electrochemical ionization of the sample of interest. The resulting odd electron sample cation (positive ion mode) or anion (negative ion mode) can then be analyzed by an appropriate technique, such as, for example, a mass spectrometer.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: July 20, 2010
    Assignees: California Institute of Technology, The United States of America
    Inventors: John R. Lloyd, Sonja Hess
  • Publication number: 20080203303
    Abstract: A single electrode electrochemical/electrospray ionization source using a corona discharge and a method of analyzing a sample using a corona discharge single electrode electrochemical/electrospray ionization source are provided. In the corona discharge single electrode electrochemical/electrospray ionization technique electrons are removed from the metal tip of the device through gases present in the electrospray ion source resulting in electrochemical ionization of the sample of interest. The resulting odd electron sample cation (positive ion mode) or anion (negative ion mode) can then be analyzed by an appropriate technique, such as, for example, a mass spectrometer.
    Type: Application
    Filed: February 27, 2008
    Publication date: August 28, 2008
    Inventors: John R. Lloyd, Sonja Hess