Patents by Inventor Sonja Klebe

Sonja Klebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Corneal cells expressing active agents and methods of use thereof
    Patent number: 7396528
    Abstract: The invention relates to methods of modifying cells of corneal tissue to express an active agent, to modified corneal tissue, to vectors utilised in such methods and to methods of xeno- and allo-transplantation utilising the modified corneal tissue. The method of modifying cells of corneal tissue to express an active agent involves exposing harvested corneal tissue to an effective concentration for transfection of an expression vector which comprises a nucleotide sequence encoding for the active agent for a period sufficient to allow infection, such that cells of the corneal tissue will express the active agent.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: July 8, 2008
    Inventors: Keryn Anne Williams, Douglas John Coster, Sonja Klebe
  • Corneal cells expressing active agents and methods of use thereof
    Publication number: 20060257382
    Abstract: The invention relates to methods of modifying cells of corneal tissue to express an active agent, to modified corneal tissue, to vectors utilised in such methods and to methods of xeno- and allo-transplantation utilising the modified corneal tissue. The method of modifying cells of corneal tissue to express an active agent involves exposing harvested corneal tissue to an effective concentration for transfection of an expression vector which comprises a nucleotide sequence encoding for the active agent for a period sufficient to allow infection, such that cells of said the corneal tissue will express the active agent.
    Type: Application
    Filed: January 30, 2006
    Publication date: November 16, 2006
    Inventors: Keryn Williams, Douglas Coster, Sonja Klebe
  • Corneal cells expressing active agents and methods of use thereof
    Publication number: 20030143212
    Abstract: The invention relates to methods of modifying cells of corneal tissue to express an active agent, to modified corneal tissue, to vectors utilised in such methods and to methods of xeno- and allo-transplantation utilising the modified corneal tissue. The method of modifying cells of corneal tissue to express an active agent involves exposing harvested corneal tissue to an effective concentration for transfection of an expression vector which comprises a nucleotide sequence encoding for the active agent for a period sufficient to allow infection, such that cells of said corneal tissue will express the active agent.
    Type: Application
    Filed: November 12, 2002
    Publication date: July 31, 2003
    Inventors: Keryn Anne Williams, Douglas John Coster, Sonja Klebe
  • Corneal cells expressing active agents and methods of use thereof
    Publication number: 20020068050
    Abstract: The invention relates to methods of modifying cells of corneal tissue to express an active agent, to modified corneal tissue, to vectors utilized in such methods and to methods of xeno- and allo-transplantation utilizing the modified corneal tissue. The method of modifying cells of corneal tissue to express an active agent involves exposing harvested corneal tissue to an effective concentration for transfection of an expression vector which comprises a nucleotide sequence encoding for the active agent for a period sufficient to allow infection, such that cells of said corneal tissue will express the active agent.
    Type: Application
    Filed: April 11, 2001
    Publication date: June 6, 2002
    Inventors: Keryn Anne Williams, Douglas John Coster, Sonja Klebe