Patents by Inventor Sonja Kleffel

Sonja Kleffel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-GITR ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20210269542
    Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to GITR and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
    Type: Application
    Filed: March 10, 2021
    Publication date: September 2, 2021
    Inventors: Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Jose-Andres Salmeron-Garcia, Heather Brodkin, Sonja Kleffel, Nels P. Nielson
  • Anti-GITR antigen-binding proteins and methods of use thereof
    Patent number: 10988545
    Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to GITR and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: April 27, 2021
    Assignee: Potenza Therapeutics, Inc.
    Inventors: Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Jose-Andres Salmeron-Garcia, Heather Brodkin, Sonja Kleffel, Nels P. Nielson
  • PROGRAMMED CELL DEATH (PD-1) INHIBITOR THERAPY FOR PATIENTS WITH PD-1-EXPRESSING CANCERS
    Publication number: 20180231554
    Abstract: Described herein are biomarkers comprising mTOR, PI3K/AKT, and MAPK/ERK signaling pathway members as well as cap-dependent translation initiation factors that enable monitoring and predicting responses to PD-1 pathway blockade in patients afflicted with cancers characterized by PD-1 expression.
    Type: Application
    Filed: September 2, 2016
    Publication date: August 16, 2018
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Tobias SCHATTON, Sonja KLEFFEL, Christian POSCH
  • Anti-GITR Antigen-Binding Proteins and Methods of Use Thereof
    Publication number: 20180208665
    Abstract: Provided herein are antigen-binding proteins (ABPs) that selectively bind to GITR and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.
    Type: Application
    Filed: February 20, 2018
    Publication date: July 26, 2018
    Inventors: Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Jose-Andres Salmeron-Garcia, Heather Brodkin, Sonja Kleffel, Nels P. Nielsen