Patents by Inventor Sonja Nordhoff
Sonja Nordhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10265310Abstract: The present invention relates to a compound according to general formula (I) which acts as a modulator of FPR2 and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by FPR2.Type: GrantFiled: September 20, 2017Date of Patent: April 23, 2019Assignee: GrÜNENTHAL GMBHInventors: Florian Jakob, Sonja Nordhoff, David Rider, Markus Wagener, Gregor Bahrenberg, Torsten Dunkern
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Publication number: 20180078541Abstract: The present invention relates to a compound according to general formula (I) which acts as a modulator of FPR2 and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by FPR2.Type: ApplicationFiled: September 20, 2017Publication date: March 22, 2018Applicant: GRÜNENTHAL GMBHInventors: FLORIAN JAKOB, SONJA NORDHOFF, DAVID RIDER, MARKUS WAGENER, GREGOR BAHRENBERG, TORSTEN DUNKERN
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Publication number: 20160151337Abstract: The invention relates to substituted bicyclic pyrroloheterocyclyl compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.Type: ApplicationFiled: February 9, 2016Publication date: June 2, 2016Inventors: Felix VOSS, Stefanie RITTER, Sonja NORDHOFF, Sebastian WACHTEN, Stefan OBERBÖRSCH, Achim KLESS
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Patent number: 9206136Abstract: The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.Type: GrantFiled: January 10, 2014Date of Patent: December 8, 2015Assignee: GRÜNENTHAL GMBHInventors: Sonja Nordhoff, Sebastian Wachten, Achim Kless, Felix Voss, Stefanie Ritter
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Patent number: 9078899Abstract: The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.Type: GrantFiled: January 10, 2014Date of Patent: July 14, 2015Assignee: GRUENENTHAL GMBHInventors: Sonja Nordhoff, Sebastian Wachten, Achim Kless, Felix Voss, Stefanie Ritter
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Publication number: 20150166505Abstract: The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to methods of using these compounds for the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.Type: ApplicationFiled: December 18, 2014Publication date: June 18, 2015Applicant: GRÜNENTHAL GMBHInventors: FELIX VOSS, SONJA NORDHOFF, SEBASTIAN WACHTEN, ANDRÉ WELBERS, STEFANIE RITTER
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Publication number: 20140194443Abstract: The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.Type: ApplicationFiled: January 10, 2014Publication date: July 10, 2014Applicant: Grünenthal GmbHInventors: Sonja Nordhoff, Sebastian Wachten, Achim Kless, Felix Voss, Stefanie Ritter
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Publication number: 20140194452Abstract: The invention relates to pyrazolyl-based carboxamide compounds useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.Type: ApplicationFiled: January 10, 2014Publication date: July 10, 2014Applicant: Grünenthal GmbHInventors: Sonja Nordhoff, Sebastian Wachten, Achim Kless, Felix Voss, Stefanie Ritter
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Patent number: 8236818Abstract: The present invention relates to substituted imidazopyridine derivatives as melanocortin-4 receptor (MC-4R) modulators, in particular as melanocortin-4 receptor antagonists. The antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, amytrophic lateral sclerosis (ALS), anxiety and depression.Type: GrantFiled: March 28, 2008Date of Patent: August 7, 2012Assignee: Santhera Pharmaceuticals (Schweiz) AGInventors: Günther Metz, Holger Deppe, Ulrich Abel, Achim Feurer, Inge Ott, Sonja Nordhoff, Michael Soeberdt, Barbara Hoffmann-Enger, Philipp Weyermann, Hervé Siendt, Christian Rummey, Miroslav Terinek, Marco Henneböhle, Holger Herzner, Cesare Mondadori
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Publication number: 20110086836Abstract: The present invention relates to substituted phenylpiperidine derivatives as melanocortin-4 receptor modulators. Depending on the structure and the stereochemistry the compounds of the invention are either selective agonists or selective antagonists of the human melanocortin-4 receptor (MC-4R). The agonists can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. Generally all diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.Type: ApplicationFiled: April 5, 2007Publication date: April 14, 2011Applicant: Santhera Pharmaceuticals (Schweiz) AGInventors: Michael Soeberdt, Holger Deppe, Philipp Weyermann, Stephan Bulat, Andreas Von Sprecher, Achim Feurer, Cyrille Lescop, Marco Hennebohle, Sonja Nordhoff
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Publication number: 20100324036Abstract: The present invention relates to substituted imidazopyridine derivatives as melanocortin-4 receptor (MC-4R) modulators, in particular as melanocortin 4 receptor antagonists. The antagonists are useful for the treatment of disorders and diseases such as cachexia induced by e.g. cancer, chronic kidney disease (CKD) or chronic heart failure (CHF), muscle wasting, anorexia induced by e.g. chemotherapy or radiotherapy, anorexia nervosa, amyotrophic lateral sclerosis (ALS), pain, neuropathic pain, anxiety and depression.Type: ApplicationFiled: December 18, 2008Publication date: December 23, 2010Applicant: SANTHERA PHARMACEUTICALS (SCHWEIZ) AGInventors: Michael Soeberdt, Philipp Weyermann, Herve Siendt, Sonja Nordhoff, Achim Feurer, Miroslav Terinek
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Publication number: 20100249093Abstract: The present invention relates to substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators. Depending on the structure and the stereochemistry the compounds of the invention are either selective agonists or selective antagonists of the human melanocortin-4 receptor (MC-4R). The agonists can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, amyotrophic lateral sclerosis (ALS), anxiety and depression. Generally all diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.Type: ApplicationFiled: July 18, 2008Publication date: September 30, 2010Applicant: SANTHERA PHARMACEUTICALS (SCHWEIZ) AGInventors: Marco Henneböhle, Holger Herzner, Michael Soeberdt, Philipp Weyermann, Sonja Nordhoff, Achim Feurer, Holger Deppe, Hervé Siendt, Miroslav Terinek, Christian Rummey
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Publication number: 20100093697Abstract: The present invention relates to substituted imidazopyridine derivatives as melanocortin-4 receptor (MC-4R) modulators, in particular as melanocortin-4 receptor antagonists. The antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, amytrophic lateral sclerosis (ALS), anxiety and depression.Type: ApplicationFiled: March 28, 2008Publication date: April 15, 2010Applicant: SANTHERA PHARMACEUTICALS (SCHWEIZ) AGInventors: Günther Metz, Holger Deppe, Ulrich Abel, Achim Feurer, Inge Ott, Sonja Nordhoff, Michael Soeberdt, Barbara Hoffmann-Enger, Philipp Weyermann, Hervé Siendt, Christian Rummey, Miroslav Terinek, Marco Henneböhle, Holger Herzner, Cesare Mondadori
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Publication number: 20080275086Abstract: The invention relates to compounds of formula (I) wherein Z, R1-7, X and n have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.Type: ApplicationFiled: February 20, 2006Publication date: November 6, 2008Inventors: Paul John Edwards, Silvia Cerezo-Galvez, Meritxell Lopez-Canet, Victor Giulio Matassa, Claudia Rosenbaum, Christian Rummey, Sonja Nordhoff
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Publication number: 20080176838Abstract: The invention relates to compounds of formula (I) wherein R1-9, Z, n, X, A, and Rb have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament for the treatment of type 2 diabetes mellitus, obesity and lipid disorders.Type: ApplicationFiled: June 8, 2005Publication date: July 24, 2008Applicant: SANTHERA PHARMACEUTICALS (DEUTSCHLAND) AGInventors: Paul John Edwards, Silvia Cerezo-Galvez, Achim Feurer, Oliver Hill, Meinolf Thiemann, Victor Giulio Matassa, Sonja Nordhoff, Meritxell Lopez-Canet
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Publication number: 20080064728Abstract: The invention relates to compounds of formula Z-C(R1R2)—C(R3NH2)—C(R4R5)-A??(I) wherein Z, R —R and A have the meaning as cited in the description and the claims as examplified by the compound (II) said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.Type: ApplicationFiled: August 3, 2005Publication date: March 13, 2008Applicant: SANTHERA PHARMACEUTICALS (SCHWEIZ) AGInventors: Paul Edwards, Silvia Cerezo-Galvez, Sonja Nordhoff
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Publication number: 20080015146Abstract: The invention relates to compounds of formula (I) wherein Z, R1-9, n, A, X and Rb have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.Type: ApplicationFiled: June 8, 2005Publication date: January 17, 2008Applicant: SANTHERA PHARMACEUTICALS (DEUTSCHLAND) AGInventors: Paul Edwards, Silvia Cerezo-Galvez, Achim Feurer, Victor Matassa, Sonja Nordhoff, Stephan Bulat, Meritxell Lopez-Canet, Christian Rummey, Claudia Rosenbaum
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Publication number: 20070265261Abstract: The invention relates to compounds of formula (1) wherein Z, R1-3 and A have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.Type: ApplicationFiled: June 8, 2005Publication date: November 15, 2007Inventors: Paul Edwards, Claudia Rosenbaum, Christian Rummey, Silvia Cerezo-Galvez, Achim Feurer, Oliver Hill, Meinolf Thiemann, Victor Matassa, Sonja Nordhoff, Barbara Hoffmann
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Publication number: 20070265301Abstract: The invention relates to compounds of formula (I), wherein Z, R1-8, n, A1, X1 and X2 have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.Type: ApplicationFiled: May 20, 2005Publication date: November 15, 2007Inventors: Paul Edwards, Victor Matassa, Achim Feurer, Sonja Nordhoff, Silvia Cerezo-Galvez, Christian Rummey
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Publication number: 20070197522Abstract: The invention relates to compounds of formula (I) Z-C(R1R2)—C(R3NH2)—C(R4R5)—X—N(R6R7)??(I), wherein Z, R1-7 and X have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.Type: ApplicationFiled: February 25, 2005Publication date: August 23, 2007Inventors: Paul Edwards, Achim Feurer, Silvia Cerezo-Galves, Victor Matassa, Sonja Nordhoff, Claudia Rosenbaum, Stephan Bulat