Abstract: Methods and apparatus providing a patient digital twin are disclosed. An example apparatus including an example patient digital twin includes a data structure created from a combination of patient electronic medical record data and historical information, the combination extracted from information system(s) and arranged in the data structure to form a digital representation of the patient. The example patient digital twin is arranged for query and simulation. The example patient digital twin is to receive feedback regarding the patient following a procedure conducted on the patient. The example patient digital twin is to incorporate the feedback into the patient digital twin when elements for the procedure have been completed. The example patient digital twin is to process the incorporated feedback to generate and output a recommendation for follow-up with respect to the patient based on the digital representation of the patient including the incorporated feedback with respect to the procedure conducted.